Bioassay and NMR-HSQC-Guided Isolation and Identification of Phthalide Dimers with Anti-Inflammatory Activity from the Rhizomes of Angelica sinensis by Hongyan Wen (9226895)

“…Among them, compound <b>9</b> showed a remarkable inhibitory activity with IC₅₀ values of 425 nM and could significantly decrease IL-1β and IL-6 transcription levels. …”

Bioassay and NMR-HSQC-Guided Isolation and Identification of Phthalide Dimers with Anti-Inflammatory Activity from the Rhizomes of Angelica sinensis by Hongyan Wen (9226895)

“…Among them, compound <b>9</b> showed a remarkable inhibitory activity with IC₅₀ values of 425 nM and could significantly decrease IL-1β and IL-6 transcription levels. …”

The differentially expressed genes in transcriptome. by Zhongjiao Liu (11877464)

Tetradentate Platinum(II) and Palladium(II) Complexes Containing Fused 6/6/6 or 6/6/5 Metallocycles with Azacarbazolylcarbazole-Based Ligands by Yuanbin She (2162245)

“…The time-dependent density functional theory (TD-DFT) calculations and natural transition orbital (NTO) analyses reveal that the Pt­(II) complexes possess 10.8–15.2% metal-to-ligand charge transfer (³MLCT) mixed with ligand-centered (³LC) characters, by contrast, the Pd­(II) complexes exhibit significantly decreased 4.2–7.1% ³MLCT characters and enhanced ³LC compositions. …”

PKM2 knockdown reduced the invasiveness of IHOK-P. by Young-Jin Park (6960)

“…<p>(a) Effects of PKM2 knockdown were separately assessed for cytoplasmic (i) and nuclear (ii) extracts following the depletion of tPKM or PKM2. …”

Platinum-Based Modification of Styrylbenzylsulfones as Multifunctional Antitumor Agents: Targeting the RAS/RAF Pathway, Enhancing Antitumor Activity, and Overcoming Multidrug Resis... by Zhikun Liu (389939)

“…Among them, compound <b>29</b> showed the most potent antitumor activity in vitro with IC₅₀ values at the nanomolar level against the tested tumor cell lines and 1000-fold higher than cisplatin against the multidrug resistant cells (A549/CDDP, A549/DOX, and SKOV-3/CDDP cells), while it showed only moderate cytotoxicity against normal cells (HEUVC cells). …”

The result of TAP-MS using PoFbx23 as the bait. by Zhongjiao Liu (11877464)

Aging of TiO₂ Nanoparticles Transiently Increases Their Toxicity to the Pelagic Microcrustacean <i>Daphnia magna</i> by Frank Seitz (122651)

“…In contrast, 6 d aged nTiO₂ in ASTM without NOM caused a fourfold decreased acute toxicity. …”

Data_Sheet_1_A Temporal Examination of Cytoplasmic Ca2 + Levels, Sarcoplasmic Reticulum Ca2 + Levels, and Ca2 + -Handling-Related Proteins in Different Skeletal Muscles of Hibernat... by Zhe Wang (41178)

“…Results showed that the level of cytoplasmic Ca²⁺ increased and SR Ca²⁺ decreased in skeletal muscle fiber during late torpor (LT) and inter-bout arousal (IBA), but both returned to summer active levels when the animals aroused from and re-entered into torpor (early torpor, ET), suggesting that intracellular Ca²⁺ is dynamic during hibernation. …”

Management of Recurrent Bronchopleural Fistula: A Multidisciplinary Approach for A Reconstructive Challenge by Karishma Chandarana (4607131)

“…<p> </p> <p>Urgent pneumonectomy for benign disease is rare but highly morbid, with a perioperative mortality approaching 50 percent. …”

The result of TAP-MS using PoAce1 as the bait. by Zhongjiao Liu (11877464)

Transcriptome analysis of secondary metabolism gene clusters of the WT and Δ<i>fbx23</i> grown in VMMG. by Zhongjiao Liu (11877464)

MVEC tubule formation requires direct contact with AoAFs. by Rebecca A. Scott (488956)

“…MVECs are depicted by CD31 (magenta), while F-actin is stained with phalloidin-568 (yellow) and nuclei are counterstained with Hoechst 33258 (cyan). Scale bar = 50 μm. In <b>A, C, & E</b>: data are represented as the mean ± SEM, with <i>n</i> = 3 biological replicates per condition. …”

Expression Profile of Six RNA-Binding Proteins in Pulmonary Sarcoidosis by Zdenka Navratilova (95970)

“…We investigated <i>in vivo</i> expression of six RBPs (AUF1, HuR, NCL, TIA, TIAR, PCBP2) and two inhibitors of proteolytic enzymes (RECK, PTEN) in pulmonary sarcoidosis and compared it to the expression in four control groups of healthy individuals and patients with other respiratory diseases: chronic obstructive pulmonary disease (COPD), asthma and idiopathic interstitial pneumonias (IIPs).…”

Long Coherence Times in Nuclear Spin-Free Vanadyl Qubits by Chung-Jui Yu (3287013)

Long Coherence Times in Nuclear Spin-Free Vanadyl Qubits by Chung-Jui Yu (3287013)

Long Coherence Times in Nuclear Spin-Free Vanadyl Qubits by Chung-Jui Yu (3287013)

GWAS analysis to assess TPC2 SNP disease association. by Julia Böck (397145)

“…Forest plots were subsequently plotted for the top five associated traits, centered around an effect size of 0. Decreasing effect sizes would suggest inverse associations between the trait and the SNP (such as for M484L and type 2 diabetes), while increasing effect sizes suggest direct associations (such as for G734E and bone mineral density). …”

Construction strategy and verification of strains Ace1/Fbx23-TAP, Δ<i>fbx23</i>, and Re<i>fbx23</i>. by Zhongjiao Liu (11877464)

GGNBP2 regulates histone ubiquitination and methylation in spermatogenesis by Kaimin Guo (4509280)

“…Furthermore, the Gametogenetin binding protein 2 deletion reduced H2B ubiquitination by affecting E2 enzymes and E3 ligase binding. …”