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Synthesis and Pharmacological Evaluation of Different Piperine Analogs for Therapeutic Potential to Prevent ER Stress
Published 2015“…Our findings indicate that exposure to tunicamycin (0.5 µg/mL) for 2 hours induces the expression of GRP78 and CHOP, and causes a significant reduction in renal cell viability. …”
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Combined Heat and Power System based on Solid Oxide Fuel Cells for hospitals in hot and humid environment.
Published 2021“…Finding optimized and sustainable solutions to the depletion of current resources and the associated CO2 emissions is one of Qatar's 2030 vision's most essential goals. …”
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Anticoagulant activity of cellulose nanocrystals from isora plant fibers assembled on cellulose and sio2 substrates via a layer-by-layer approach
Published 2021“…In this study, we report the isolation of cellulose nanocrystals (CNCs) from Isora plant fibers by sulfuric acid hydrolysis and their assembly on hydrophilic cellulose and silicon-di-oxide (SiO2) surfaces via a layer-by-layer (LBL) deposition method. …”
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Effect of BPA on CYP450s expression, and nicotine modulation, in fetal rat brain
Published 2022“…Fetal brains were isolated at gestational days GD14 and GD19, and protein expression was assessed by Western blotting. Results showed a BPA-induced significant decrease in CYP1B1 expression levels at GD14 (p = 0.001), and CYP19A1 (aromatase) expression at both mid- and late-stage development (p < 0.001). …”
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Structural and mechanical characterization of stir cast Al–Al2O3–TiO2 hybrid metal matrix composites
Published 2020“…Scanning electron microscopy shows that aluminium matrix has uniform distribution of reinforcement particle i.e. aluminium oxide and titanium oxide. Density of composite decreases due to variation of reinforcement and it shows low density after preheating. …”
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Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach
Published 2017“…Maturity-onset diabetes of the young type 3 (MODY3) is a non-ketotic form of diabetes associated with poor insulin secretion. …”
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Tailoring the deposition of MoSe2 on TiO2 nanorods arrays via radiofrequency magnetron sputtering for enhanced photoelectrochemical water splitting
Published 2023“…In particular, the sample synthesized by sputtering of MoSe2 for 90 s, i.e., MoSe2@TiO2-90 s, depicted the highest current density (1.86 mA cm−2 at 0.5 V vs. …”
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Structure–activity relationship of piperine and its synthetic amide analogs for therapeutic potential to prevent experimentally induced ER stress in vitro
Published 2017“…Pre-treatment of cells with piperine and its cyclohexylamino analog decreased the tunicamycin-induced upregulation of GRP78 and CHOP and cell death. …”
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51
Two-stage cultivation of a Nannochloropsis mutant for biodiesel feedstock
Published 2015“…The fatty acid profile of MT-I5 also had an increased level of desirable saturated fatty acids (SFA) for use as a biodiesel feedstock, i.e. from 43 to 48�% of TFA, as well as a decreased level of less desirable polyunsaturated fatty acids (PUFA), i.e. from 22 to 7�% of TFA. …”
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52
Elaeagnus angustifolia Plant Extract Inhibits Epithelial-Mesenchymal Transition and Induces Apoptosis via HER2 Inactivation and JNK Pathway in HER2-Positive Breast Cancer Cells
Published 2020“…Meanwhile, the outcome of extract on HER2-positive breast cancer remains nascent. Thus, we herein investigated the effects of the aqueous extract obtained from the flowers of on two HER2-positive breast cancer cell lines, SKBR3 and ZR75-1. …”
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The influence of environmental and core temperature on cyclooxygenase and PGE2 in healthy humans
Published 2021“…Whether cyclooxygenase (COX)/prostaglandin E2 (PGE2) thermoregulatory pathways, observed in rodents, present in humans? …”
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Role of TiO2 and carbon nanotubes on polyethylene, and effect of accelerated weathering on photo oxidation and mechanical properties
Published 2019“…Addition of CNTs had negligible effect on the tensile strength but it kept the same approximate value of the original before the accelerated weathering (e.g., 23.2 MPa for 1 wt% of CNTs). CNTs also protected the samples even with the presence of TONPs because of the absorbance and antioxidants effects. …”
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Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects
Published 2019“…This was associated with a marked decrease (50%) in the expression of detoxifying genes (NQO1 and GSTA1) with an increase in CYP1A1 mRNA expression, a cancer-activating gene. …”
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Electrocatalytic arsenite oxidation in bicarbonate solutions combined with CO2 reduction to formate
Published 2020“…However, the application of a potential higher than the peak (E > Ep,As) leads to a significant decrease in the FE due to water oxidation. …”
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