Table1_Effectiveness of dapagliflozin as an insulin adjunct in type 1 diabetes: a semi-mechanistic exposure-response model.DOC by Victor Sokolov (14181554)

“…Even so, this association remained flat, with a 50% decrease in the basal insulin dose from pretreatment level, resulting in ∼5% increase in glucose exposure. …”

Beta 2-adaptin is required for directed cell migration. by Jeanine Pignatelli (130432)

“…Beta2-adaptin knockdown results in decreased wound closure. …”

PCA ordination diagram of all 76 study plots of vegetation based on six explanatory variables, with differentiation of the three groups of plots presented with different colors and... by Remigiusz Pielech (98386)

Overexpression of Rab26 restricts insulin secretion in β-cells. by Ruijuan Zhuang (3938915)

“…Supernatant insulin secretion was measured by ELISA, corresponding AUCs of MIN6 (B) or INS-1 (D) cells insulin release stimulated by 16.7 mM glucose stimulated. (E) INS-1 cells were infected with Ad-Rab26WT, Ad-Rab26T77N, Ad-Rab26Q123L, and Ad-vector, balanced with 2.8 mM glucose in KRBH buffer for 1 h, then stimulated with 16.7 mM glucose in KRBH buffer for 30 min. …”

LCHD induced impaired glucose tolerance, insulin resistance and fat accumulation. by Kuralay Atageldiyeva (3165285)

Joint and conditional probability maps. by Marcus H. C. Howlett (3921143)

DataSheet1_Macleayins A From Macleaya Promotes Cell Apoptosis Through Wnt/β-Catenin Signaling Pathway and Inhibits Proliferation, Migration, and Invasion in Cervical Cancer HeLa Ce... by Chunmei Sai (11240097)

“…The Wnt/β-catenin signaling cascade activation was verified using the Dual-Glo® Luciferase assay. We found that MA inhibited the growth of HeLa cells at 72 h (IC₅₀ = 26.88 µM) via inducing apoptotic process, reduced the proliferation rate by 29.89%, and decreased the cells migration and invasion as compared to the untreated group. …”

PIK3C3 promotes <i>Shigella flexneri</i> cell-to-cell spread through resolution of VLPs into DMVs. by Steven J. Rolland (21376879)

Neither oxidative stress, nor Mec1/Rad53-dependent induction of <i>DIN7</i> expression determines the increase in E^R mutations in Rad27 deficient yeast. by Aneta Kaniak-Golik (4225384)

“…Overexpression of <i>CTA1</i> does not decrease the E^R mutation frequency in a <i>rad27</i>Δ strain. …”

L- and M-cones adapt to contrast—natural time series of chromatic intensity (NTSCI). by Marcus H. C. Howlett (3921143)

LBH589 treatment inhibited the growth of SK-NEP-1 xenograft tumors in nude mice. by Tao Yan-Fang (770096)

“…Ten days after injection, mice were treatment with PBS, DMSO, and LBH589 10mg/kg and 20mg/kg dose. (A) To clearly demonstrate that LBH589 causes apoptosis in SK-NEP-1 and G401 cells, we assessed the expression of PARP, caspase 3, caspase 9 and Bcl-2, recognized markers of apoptosis by western blotting. …”

Competition of gene-sweep and diversity-restoring dynamics affects the minimal and maximal observed diversity. by Simone Pompei (134652)

“…The dynamics of diversity after the emergence of a beneficial gene is characterized by two time scales: (i) the time until the beneficial gene reaches fixation (<i>τ</i>_fix), during which the diversity drops and (ii) an equilibration time (<i>τ</i>_eq), restoring its initial value. …”

Participants completed two precision grip force tasks. by Kristina A. Neely (387903)

“…B: the visual display contained two horizontal bars presented against a high contrast black background. …”

DataSheet1_Predicting the solubility of CO2 and N2 in ionic liquids based on COSMO-RS and machine learning.docx by Hongling Qin (5557505)

“…To further improve the performance of COSMO-RS, two options were used, i.e., the polynomial expression to correct the COSMO-RS results and the combination of COSMO-RS and machine learning algorithms (eXtreme Gradient Boosting, XGBoost) to develop a hybrid model. …”

Image_2_Targeting MAPK Pathways by Naringenin Modulates Microglia M1/M2 Polarization in Lipopolysaccharide-Stimulated Cultures.TIF by Bei Zhang (428038)

“…Then, NAR shifted the M1 pro-inflammatory microglia phenotype to the M2 anti-inflammatory M2 microglia state as demonstrated by the decreased expression of M1 markers (i.e., inducible TNF-α and IL-1β) and the elevated expression of M2 markers (i.e., arginase 1, IL-4, and IL-10). …”

Differential expression of genes beneath QTL mapped in pA. by Michael A. Najarro (831657)

Cell proliferation analysis. by Jinglin Zhang (685704)

“…<p>A, B, C) BrdU incorporation assay in E13.5 <i>WT</i> and <i>Fgfr2</i>^<i>CKO</i> mice demonstrated that BrdU-positive cells were significantly reduced in the corneal epithelium of <i>Fgfr2</i>^<i>CKO</i> mice as compared to <i>WT</i> mice. …”

Neutralisation assays. by Claudia Pommerenke (150761)

“…<p>Neutralising SARS-CoV-2 antibody was applied to the high permissive cell lines CAL-51 and CL-14 and the control cell line VERO-E6. …”

Inhibition of SIRT1/2 by sirtinol induces senescence in BJ fibroblasts. by Mehtap Kilic Eren (591048)

Doxorubicin induced senescence is associated with reduced SIRT1and SIRT2 levels. by Mehtap Kilic Eren (591048)