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The rate of lariat formation is decreased two-fold by isoginkgetin treatment.
Published 2014“…RNA-Seq density is normalized as read counts per 10M uniquely aligning reads. The indicated values are from an average of three biological replicates, and <i>p</i>-values are from two-tailed <i>t</i>-tests based on mean values for aggregated introns 2–10 (n = 9). …”
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Resveratrol decreases PKM2 expression.
Published 2013“…<p>Resveratrol treatment decreases PKM2 mRNA in (A), HeLa; (B), HepG2 and (C), MCF-7; by approximately two-folds. β-actin was taken as endogenous control and normalized to PKM2 mRNA. …”
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HRMECs treated with SUZ12 siRNA demonstrate increased miR-200b expression, decreased VEGF expression and decreased endothelial branching.
Published 2015“…<p><b>A,B:</b> Gene knockdown of EZH2 and SUZ12 was confirmed by qPCR. <b>C,D:</b> In HRMECs transfected with EZH2 siRNA in HG, miR-200b and VEGF were not significantly different from HG+control siRNA but decreased compared to NG+control siRNA. …”