Design of Benzyl-triazolopyrimidine-Based NADPH Oxidase Inhibitors Leads to the Discovery of a Potent Dual Covalent NOX2/MAOB Inhibitor by Beatrice Noce (16540800)

“…We found that <b>9a</b>, bearing a pargyline moiety, is also able to selectively inhibit MAOB over MAOA (465-fold) with an IC₅₀ of 0.182 μM, being the first-in-class dual NOX2/MAOB covalent inhibitor. …”

TEM4 depletion decreases TEM4 mRNA and protein levels but no effect on spindle staining by the TEM4 antibody. by Diogjena Katerina Prifti (12988141)

Shoot-to-root translocation of GmNN1/FT2a regulates soybean nodulation. by Xinxin Li (281237)

Image_3_A Shift in Myeloid Cell Phenotype via Down Regulation of Siglec-1 in Island Macrophages of Bone Marrow Is Associated With Decreased Late Erythroblasts Seen in Anemia of Cri... by Shirin Hasan (7894118)

“…There were more (2.5-fold) EEBs and less LEBs (2.4-fold) per million TBM cells in B; with a corresponding decrease in Siglec-1 and Ly6G expressions in EBIMØ associated with EEB. …”

Image_4_A Shift in Myeloid Cell Phenotype via Down Regulation of Siglec-1 in Island Macrophages of Bone Marrow Is Associated With Decreased Late Erythroblasts Seen in Anemia of Cri... by Shirin Hasan (7894118)

“…There were more (2.5-fold) EEBs and less LEBs (2.4-fold) per million TBM cells in B; with a corresponding decrease in Siglec-1 and Ly6G expressions in EBIMØ associated with EEB. …”

Intracellular levels of HSPG core proteins, HS and HPSE are decreased in ER stressed MIN6 cells. by Sarita Dhounchak (10924448)

Fe limitation decreases transcriptional regulation over the diel cycle in the model diatom <i>Thalassiosira pseudonana</i> - Fig 2 by Johanna A. L. Goldman (7372724)

Illustrations of the SeqFold2D network and the Stralign dataset. by Xiangyun Qiu (316117)

Cycloheximide (CHX) treatment decreases production of rRNA transcripts by POLR1 and POLR3. by Martin Selinger (3195987)

“…<p>(A) DAOY cells were treated with CHX (100 μg/ml) for either 6 or 14 hours; for metabolic RNA labelling, 5-EU was added 2 hours before the sample collection. …”

Effects of SNPs on the Protein Stability, Increasing or Decreasing. by Mirza Jawad Ul Hasnain (8351388)

Table 2_Increased frequencies of human Th-17 CD4+ T-cells and decreased T-regulatory cells in patients with early and advanced metabolic dysfunction-associated steatotic liver dise... by Elżbieta Supruniuk (16736637)

Proinflammatory signaling pathways were decreased in Ad26.COV2.S vaccinated compared to sham unvaccinated hamsters. by Malika Aid (7303874)

“…<p><b>(A)</b> Boxplots of SARS-CoV-2 transcripts normalized read counts across all animals, vaccinated hamsters are shown in blue and pink, and sham animals in green. …”

Data_Sheet_2_Serological Levels of Anti-clathrin Antibodies Are Decreased in Patients With Pseudoexfoliation Glaucoma.docx by Vanessa M. Beutgen (6432671)

Characteristics of EF1-driven single copy NR1I2, NR4A1, or RORA stably-transfected cells. by Yoshinori Hasegawa (308240)

Subjects:

Relative expression (fold-change) of immune genes in mitogen-stimulated splenic lymphocytes. by Chaiwat Monmai (6377270)

Three Ca_V3.3 variants left-shift the window current, while the A398V completely abolishes the window current. by Yousra El Ghaleb (22075892)

Subjects:

Data Sheet 1_Elevated relative humidity significantly decreases cannabinoid concentrations while delaying flowering development in Cannabis sativa L..docx by Ingrid Carolina Corredor-Perilla (22631510)

“…Furthermore, high RH significantly suppressed cannabinoid accumulation: cannabidiolic acid (CBD-A), cannabidiol (CBD), and cannabichromenic acid (CBC-A) levels decreased by approximately 4.9-fold, 3.2-fold, and 13-fold, respectively. …”

RT-qPCR analysis of congenital diaphragmatic hernia lungs showed an increase in distal epithelial progenitor and a decrease in type 1 alveolar cells. by Tram Mai Nguyen (6597863)

“…<p>E17.5 CDH lungs demonstrated a decrease in mRNAs identifying alveolar epithelial type I cells (<i>Hopx</i>, <i>Pdpn</i>) while distal epithelial progenitor marker <i>Id2</i> was increased. …”

VPS34 inhibition decreases intracellular levels of cholesteryl-esters, blocks cholesterol uptake and enhances lysosomal degradation of LDLR. by Marek J. Kobylarz (9292599)

Mononucleation of the intestine causes an X chromosome specific decrease in expression levels. by Lotte M. van Rijnberk (3716362)