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Administration of a Toll-Like Receptor 9 Agonist Decreases the Proviral Reservoir in Virologically Suppressed HIV-Infected Patients
Published 2013“…We observed a mean reduction in proviral DNA in the CPG group of 12.6% (95% CI: −23.6–0.0) following each immunization whereas proviral DNA in the placebo-adjuvant group remained largely unchanged (6.7% increase; 95% CI: −4.2–19.0 after each immunization, p = 0.02). …”
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EGR1 decreased expression of <i>uPA</i> and <i>uPAR</i>.
Published 2011“…Real-time PCR revealed that forced expression of EGR1 decreased <i>uPA</i> and <i>uPAR</i> expression in 143B, Saos-2, and HOS cells (P<0.05). …”
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Gene ontology biological processes overrepresented among genes exhibiting decreased expression in human psoriasis.
Published 2011“…<p>A total of 3540 transcripts were identified as significantly decreased in psoriatic plaques obtained from human patients relative to normal skin obtained from control subjects (FDR-adjusted P<0.05 and log<sub>2</sub>-transformed fold-change less than -0.50). …”
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Cycloheximide (CHX) treatment decreases production of rRNA transcripts by POLR1 and POLR3.
Published 2019“…<p>(A) DAOY cells were treated with CHX (100 μg/ml) for either 6 or 14 hours; for metabolic RNA labelling, 5-EU was added 2 hours before the sample collection. …”
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