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Hepatic Expression of Detoxification Enzymes Is Decreased in Human Obstructive Cholestasis Due to Gallstone Biliary Obstruction
Published 2015“…The levels of membrane transporters, OSTβ and OCT1, were increased 10.4-fold and 1.8-fold, respectively, (<i>p</i><0.05), whereas those of OSTα, ABCG2 and ABCG8 were all decreased by approximately 40%, (<i>p</i><0.05) in human cholestatic livers. …”
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Macroscopic and histological assessment of colic tumor and inflammation in mice.
Published 2020Subjects: -
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GSK343 decreased neuroblastoma viability, proliferation, and motility.
Published 2021“…<p>(A) SK-N-AS, SK-N-BE(2), SH-EP and WAC(2) cells (1.5 × 10<sup>3</sup> cells) were treated with increasing concentrations of GSK343 (0, 5, 15, 25 μM) for 24 hours and viability was measured using alamarBlue<sup>®</sup> assay. …”
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HRMECs treated with SUZ12 siRNA demonstrate increased miR-200b expression, decreased VEGF expression and decreased endothelial branching.
Published 2015“…<p><b>A,B:</b> Gene knockdown of EZH2 and SUZ12 was confirmed by qPCR. <b>C,D:</b> In HRMECs transfected with EZH2 siRNA in HG, miR-200b and VEGF were not significantly different from HG+control siRNA but decreased compared to NG+control siRNA. …”
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GREAT GO analysis of WDR5 and MYCN overlapped ChIP-seq peaks with >2.5-fold decrease of WDR5 signal intensity after the silencing of <i>WDR5</i>.
Published 2024“…<p>GREAT GO analysis of WDR5 and MYCN overlapped ChIP-seq peaks with >2.5-fold decrease of WDR5 signal intensity after the silencing of <i>WDR5</i>.…”
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ASM Ca<sup>2+</sup> signaling receptors expression decreased with age.
Published 2021“…ASM isolated from elderly patients (>65) had significantly decreased M<sub>3</sub> muscarinic receptor (A), histamine receptor (B), SERCA2 (G), and Orai1 (H) expression. …”