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nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
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Childhood tuberculosis is associated with decreased abundance of T cell gene transcripts and impaired T cell function
Published 2017“…Findings were validated in a second cohort with concordance of the direction of differential expression in both TBM (r<sup>2</sup> = 0.78 p = 2x10<sup>-16</sup>) and PTB patients (r<sup>2</sup> = 0.71 p = 2x10<sup>-16</sup>) when compared to a second group of healthy controls. …”
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WT1 siRNA decreases proliferation, pAKT, and Bcl2 expression.
Published 2024“…Corresponding densitometry analysis is noted as protein fold expression compared to GAPDH for WT1, p<0.001(***), vFLIP(ns), LANA p<0.05(*), pAKT p<0.05(*), and BCL2 p <0.05(*) using two-sided, unpaired student t-tests. …”
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Discovery of Triazolyl Derivatives of Cucurbitacin B Targeting IGF2BP1 against Non-Small Cell Lung Cancer
Published 2023“…Derivative <b>A11</b> directly binds to the insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) protein with a <i>K</i><sub>D</sub> value of 2.88 nM, which is about 23-fold more potent than CuB, leading to the decreased expression of downstream apoptosis- and cell cycle-related proteins. …”
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(R)-albuterol decreases cytokine mRNA levels in activated T cells
Published 2011“…RNA was isolated. Levels of IL-2, IL-13 and IL-6 (A, B, C) were measured by real time PCR. …”