Potential effect of the differential genetic expression of PBMCs. by Michael J. Baine (230373)

“…<p>All genes shown were found to be down-regulated greater than 1.5 fold. The respective amount of differential expression per gene as well as the stated function can be found in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0017014#pone-0017014-t003" target="_blank">Table 3</a>. …”

Supporting main Fig 2. by Jyoti Tanwar (2230597)

“…<p><b>MCU positively regulates melanogenesis while MCUb negatively controls melanogenesis. (A)</b> Quantitation of resting mitochondrial Ca²⁺ with CEPIA2mt in siNT control and siMCUb B16 cells stimulated with 100 μm histamine. …”

Summary of the in vitro and in vivo characterization of PCNA mutants. by Yearit Fridman (240019)

“…</p>c<p>Fold increase or decrease in the PCNA-partner interaction affinities measured as the generation time of the Y2H strains grown in liquid selective media lacking histidine, relative to cells expressing WT PCNA (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1000507#pbio.1000507.s004" target="_blank">Figures S4</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1000507#s4" target="_blank">Materials and Methods</a>).…”

CPZ pretreatment inhibits cleaved caspase-3 expression in rat brains after ethanol exposure. by Jing Wu (54032)

“…All three doses of CPZ result in a significant decrease of the cleaved caspase-3 levels compared with ethanol group.…”

Intraplantar acid injection produced TRPV1-mediated time-dependent behavioral hyperalgesia and spinal neuron sensitization. by He Liu (67509)

“…Intraplantar injection of SB366791 (2.5-µg/10-µl)+pH 5.0 PBS (10-µl), not amiloride(100-µg/10-µl)+pH 5.0 PBS and DMSO (1%/10-µl)+pH 5.0 PBS (10-µl) group decreased spinal Fos protein expression. …”

Pharmacokinetics and pharmacodynamics after treatment of DIO-mice with HI, X10 and IGF-1 by sc injection. by Henning Hvid (486358)

“…Maximal plasma concentrations were measured 15 min after treatment. 6 h after treatment plasma concentrations of IGF-1 were ≈ 100 fold higher than plasma concentrations of HI and X10. …”

Percent reduction in the relative transcript levels due to target gene silencing in the females of <i>M</i>. <i>incogntia</i> feeding on the transgenic plants. by Pradeep Kumar Papolu (480570)

“…<i>18S </i><i>rRNA</i> was used as a reference gene and fold change was calculated by using 2^-ΔΔCT method. …”

Statistical comparison of the global tolerances of NADPH redox cycles harboring G6PD variants that belong to different classes. by Pedro M. B. M. Coelho (240895)

“…</p><p>§[T represents tolerance to a fold decrease and T] represents tolerance to a fold increase.…”

Proteins from the TSC/mTOR pathway are regulated by p19. by Maria Camats (255397)

“…D) western blot analysis with anti-FOXO1 antibodies of extracts from HeLa cells transfected with pRK5, pRK5-p19 and pRK5-p19mut. A 2-fold increase of FOXO1 was quantified in lanes pRK5-p19 versus pRK5.…”

Validation of RNA sequencing by RT-qPCR. by Olga Østrup (408062)

“…<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0061547#pone-0061547-g001" target="_blank">Figure 1A</a> shows the validation results for genes identified as enriched at 2-cell stage. Grey bars named Bc qPCR show fold changes between blastocyst/2-cell stages and demonstrate the tendency towards continuous decrease in the amount of these transcripts. …”

Translational control in the long-lived ER secretory pathway mutants. by Vyacheslav M. Labunskyy (505446)

“…Changes in log2 TE are shown for all genes that showed more than 1.5-fold decrease or increase in TE. …”

TGFβ signaling promotes NDR1 turnover. by Isabelle Pot (427025)

“…Data are presented as the mean+SEM (n = 4) of percent decrease in protein abundance of NDR1 in NMuMG cells in response to TGFβ. …”

Supporting data for "Excess mortality during the COVID-19 pandemic in Hong Kong and South Korea" by Shuqi Xu (12992556)

“…Mortality from influenza and pneumonia was estimated to have a statistically significant increase in HK but a decrease in SK probability due to different coding practices. …”

<i>F. novicida</i> deletion mutants of a putative transglutaminase are severely attenuated in virulence and growth. by Madeleine G. Moule (243057)

“…The difference between the mean number of CFUs of wild-type and FTN_0869 has decreased at every timepoint, with only a 2.9-fold increase in wild-type bacteria compared to FTN_0869 bacteria at 24 hours, 6-fold more bacteria in U112 infected flies at 48 hours, and only 4-fold more U112 bacteria than FTN_0869 bacteria at 72 hours. …”

Summary of the TAFV challenge study results through 15 days post challenge (study day 70–85). by Kelly L. Warfield (130405)

“…<i>0°F below baseline; mild rash = focal areas of petechiae covering less than 10% of skin; moderate rash = areas of petechiae covering between 10% and 40% of the skin; severe rash = areas of petechiae or ecchymosis covering more than 40% of the skin</i></p><p><i>↑</i>, <i>2- to 3-fold increase</i></p><p><i>↑↑</i>, <i>4- to 5-fold increase</i></p><p><i>↑↑↑</i>, <i>> 5-fold increase</i></p><p><i>↓</i>, <i>2- to 3-fold decrease</i></p><p><i>WL</i>: <i>weight loss was the percentage compared to the weight at study initiation; BUN</i>: <i>blood urea nitrogen; ALT</i>: <i>alanine aminotransferase; AST</i>: <i>aspartate aminotransferase; ALP</i>: <i>alkaline phosphatase; ALB</i>: <i>albumin</i>, <i>Glu</i>: <i>glucose</i>, <i>Cre</i>: <i>creatinine</i>, <i>WBC</i>: <i>white blood cells; Plt</i>: <i>platelet</i>, <i>Lym</i>: <i>lymphocyte</i>.…”

Effects of insulin and IGF-I stimulation on the expression levels of bisecting GlcNAc <i>N</i>-glycans, in general and specifically on E-cadherin. by Julio Cesar Madureira de-Freitas-Junior (489189)

“…MDA-MB-435+E-cad cells stimulated with insulin (100 ng/mL) and IGF-I (50 ng/mL) showed a significant decrease of the overall levels of bisecting GlcNAc N-glycans. …”

Hepatoprotective and antioxidant effect of ellagitannins and galloyl esters isolated from <i>Melaleuca styphelioides</i> on carbon tetrachloride-induced hepatotoxicity in HepG2 cel... by Eman Al-Sayed (2934060)

“…(Myrtaceae) showed a significant hepatoprotective effect in a CCl₄-induced toxicity model in mice. …”

Gene expression profiling of FP^hi, FP^lo and adenoma cells. by Yoshihisa Okuchi (3098121)

“…Here, genes up- or downregulated in adenoma cells were defined as those genes whose expression levels were increased by 2.0-fold or decreased by 1.5-fold compared with those in FP^hi cells. …”

CTR1 silencing inhibits mRNA and protein expression. by Gomathy Narayanan (456259)

“…CTR1 ELISA: HUVECs were treated with Cu 100 µM showed a significant (# <i>p</i> = 0.05) increase in CTR1 protein level compared to control and si 1 10 nM showed a significant decrease (* <i>p</i> = 0.04) in protein level when compared to Cu. …”

Real time PCR validation of ESFT fusion protein- and wild type FLI-1 and ERG-1-induced and repressed genes 36 hours following infection by Luisa Cironi (51676)

“…Lower than two-fold increases or decreases in absolute value are indicated.as <i></i></p>…”