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Inflammation and hyperoxia decreases MBP expression.
Published 2012“…<p>A significantly decrease of MBP protein expression as a sign of hypomyelination occurs in all experimental settings with similar severity. …”
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Expression of coilin decreases neurite outgrowth.
Published 2013“…For statistical evaluation, averaged relative neurite lengths of n>100 cells were compared, pooled from three individual experiments (means ± SEM; n.s.; A: **, p<0.01; Mann-Whitney test; B: n.s., non-significant; *, p<0.05; **, p<0.01; ***, p<0.001; Dunn’s test for comparison of multiple groups).…”
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GSK3 inhibition results in a decrease of p-β-Catenin.
Published 2015“…Only the treatment with 2 and 10 μM of AR-A014418 decreased p-β-Catenin levels. The co-treatment with the PI3K activator did not induce a further reduction. …”
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GSK343 treatment decreased <i>in vivo</i> tumor volume and growth.
Published 2021“…Tumor volumes were monitored three times per week. (A) Animals treated with GSK343 had significantly decreased fold change in tumor volumes compared to mice treated with vehicle. …”
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CsA reduces Flk1 protein expression and significantly decreases the percentages of Flk1+ cells.
Published 2015“…Scale bars = 100 μm. (C) Representative flow cytometry profiles showing the decreased percentages of Flk1+ cells in P19 cells treated with 0.32 μM CsA during EB formation for 48 and 96 h, respectively. …”