Supplementary Material for: Tocilizumab Treatment Effect on Iron Homeostasis in Severe COVID-19 Patients by Guz D. (12023726)

Fig 3 - by Nasser Semmo (76848)

“…The decrease in mean FSS score from baseline (Day 1) to Day 28, Day 84 and 12 weeks post-treatment (Day 168) is shown for (d) the sdITT population and (e) the mITT population. ° = outlier (value maximum 1.5 to 3 fold box length); FSS = fatigue severity scale, mITT = modified intention to treat; sdITT = scaled down intention to treat; V = study visit.…”

DataSheet_1_Expression of Senescence Marker TIGIT Identifies Polyfunctional Donor-Reactive CD4+ T Cells Preferentially Lost After Kidney Transplantation.docx by Amy C. J. van der List (9343289)

“…Unexpectedly, our results do not demonstrate an increase in exhausted donor antigen-reactive T cells post transplantation. Instead, we demonstrate a significant decrease in donor antigen-reactive CD4+ T cells expressing T cell immunoglobulin and ITIM domain (TIGIT) long after transplantation. …”

Table_1_Neuromodulation With Thoracic Dorsal Root Ganglion Stimulation Reduces Ventricular Arrhythmogenicity.pdf by Yuki Kuwabara (8964737)

“…DRGS also reduced arrhythmogenicity as measured by a decrease in S_max (20 Hz DRGS 0.5 ± 0.07, Control 0.7 ± 0.04, P = 0.006; 1 kHz DRGS 0.5 ± 0.04, Control 0.7 ± 0.03, P = 0.007), and a decrease in Tp-Te interval/QTc (20 Hz DRGS 2.7 ± 0.13, Control 3.3 ± 0.12, P = 0.001; 1 kHz DRGS 2.8 ± 0.08, Control; 3.1 ± 0.03, P = 0.007).…”

Superovulation alters global DNA methylation in early mouse embryo development by Bo Yu (241082)

“…Zygotes and 8-cell embryos were collected from each group and DNA methylomes were generated by whole-genome bisulfite sequencing. In the NM group, mean CpG methylation levels slightly decreased from zygote to 8-cell stage, whereas a large decrease in mean CpG methylation level was observed in both superovulated groups. …”

Image2_Hippocampal versus cortical deletion of cholinergic receptor muscarinic 1 in mice differentially affects post-translational modifications and supramolecular assembly of resp... by Mohammad Golam Sabbir (15874493)

“…IEF of ECMFs and EHMFs from Chrm1^−/− mice showed a decrease and an increase, respectively in a negatively charged (pH∼3) fraction of Atp5a relative to the wild-type mice, with a corresponding decrease or increase in the supramolecular assembly of Atp5a and respiration indicating a tissue-specific signaling effect.…”

Image3_Hippocampal versus cortical deletion of cholinergic receptor muscarinic 1 in mice differentially affects post-translational modifications and supramolecular assembly of resp... by Mohammad Golam Sabbir (15874493)

“…IEF of ECMFs and EHMFs from Chrm1^−/− mice showed a decrease and an increase, respectively in a negatively charged (pH∼3) fraction of Atp5a relative to the wild-type mice, with a corresponding decrease or increase in the supramolecular assembly of Atp5a and respiration indicating a tissue-specific signaling effect.…”

Image4_Hippocampal versus cortical deletion of cholinergic receptor muscarinic 1 in mice differentially affects post-translational modifications and supramolecular assembly of resp... by Mohammad Golam Sabbir (15874493)

“…IEF of ECMFs and EHMFs from Chrm1^−/− mice showed a decrease and an increase, respectively in a negatively charged (pH∼3) fraction of Atp5a relative to the wild-type mice, with a corresponding decrease or increase in the supramolecular assembly of Atp5a and respiration indicating a tissue-specific signaling effect.…”

Image1_Hippocampal versus cortical deletion of cholinergic receptor muscarinic 1 in mice differentially affects post-translational modifications and supramolecular assembly of resp... by Mohammad Golam Sabbir (15874493)

“…IEF of ECMFs and EHMFs from Chrm1^−/− mice showed a decrease and an increase, respectively in a negatively charged (pH∼3) fraction of Atp5a relative to the wild-type mice, with a corresponding decrease or increase in the supramolecular assembly of Atp5a and respiration indicating a tissue-specific signaling effect.…”

datasheet1_Aftershock Rate Changes at Different Ocean Tide Heights.pdf by P. N. Shebalin (9898970)

“…This suggests two main mechanisms of the impact of ocean tides on seismicity rate, an increase in pore pressure at high water, or a decrease in normal stress at low water, both resulting in a decrease of the effective friction in the fault zone.…”

Genes significantly affected by deletion of <i>ryfA</i>. by Hicham Bessaiah (6840980)

“…Dark blue is greater or equal to (≥) a 3-fold decrease. Light blue is a decrease from 3-fold to 1.7-fold. …”

Table_2_MdGGT1 Impacts Apple miR156 Precursor Levels via Ontogenetic Changes in Subcellular Glutathione Homeostasis.DOC by Yakun Chen (4794774)

“…Manipulating GGT activity and GSH homeostasis by transgenic over-expressing or RNAi MdGGT1 increased or decreased MdMIR156a5 and MdMIR156a12 levels, respectively. …”

Table_1_MdGGT1 Impacts Apple miR156 Precursor Levels via Ontogenetic Changes in Subcellular Glutathione Homeostasis.DOC by Yakun Chen (4794774)

“…Manipulating GGT activity and GSH homeostasis by transgenic over-expressing or RNAi MdGGT1 increased or decreased MdMIR156a5 and MdMIR156a12 levels, respectively. …”

Heterogeneous Effects of Forced Migration on the Female Labor Market: The Venezuelan Exodus in Colombia by Julian Pedrazzi (14131481)

“…When testing the underlying mechanisms of this latter result, we find a reduction in the time spent on childcare and an increase in the probability of hiring domestic service, explained by a decrease in the cost of this service due to the Venezuelan exodus.…”

Elevated forest cover is linked to declining topsoil pH and amplified <i>p</i>CO₂ in U.S. lakes by Yongqiang Zhou (11551027)

“…This can largely be attributed to a decrease in topsoil pH (a 10% greater forest cover is associated with a 0.2-unit decrease in topsoil pH), which acidifies downstream lakes and shifts the carbonate equilibrium toward dissolved CO₂. …”

Morbidity and mortality of pancreatic tumors undergoing surgical treatment by Luiza Bueno ZENI (12742923)

“…The prognosis is poor, with 5-year survival occurring in less than 5% of cases. …”

DataSheet_2_Single-Arm, Multicenter Phase I/II Clinical Trial for the Treatment of Envenomings by Massive Africanized Honey Bee Stings Using the Unique Apilic Antivenom.docx by Alexandre Naime Barbosa (4830609)

“…<p>We evaluated the safety, optimal dose, and preliminary effectiveness of a new-approach Africanized honeybee (Apis mellifera) Antivenom (AAV) in a phase I/II, multicenter, non-randomized, single-arm clinical trial involving 20 participants with multiple stings. …”

DataSheet_3_Single-Arm, Multicenter Phase I/II Clinical Trial for the Treatment of Envenomings by Massive Africanized Honey Bee Stings Using the Unique Apilic Antivenom.docx by Alexandre Naime Barbosa (4830609)

“…<p>We evaluated the safety, optimal dose, and preliminary effectiveness of a new-approach Africanized honeybee (Apis mellifera) Antivenom (AAV) in a phase I/II, multicenter, non-randomized, single-arm clinical trial involving 20 participants with multiple stings. …”

DataSheet_1_Single-Arm, Multicenter Phase I/II Clinical Trial for the Treatment of Envenomings by Massive Africanized Honey Bee Stings Using the Unique Apilic Antivenom.docx by Alexandre Naime Barbosa (4830609)

“…<p>We evaluated the safety, optimal dose, and preliminary effectiveness of a new-approach Africanized honeybee (Apis mellifera) Antivenom (AAV) in a phase I/II, multicenter, non-randomized, single-arm clinical trial involving 20 participants with multiple stings. …”

Video_1_Single-Arm, Multicenter Phase I/II Clinical Trial for the Treatment of Envenomings by Massive Africanized Honey Bee Stings Using the Unique Apilic Antivenom.mp4 by Alexandre Naime Barbosa (4830609)

“…<p>We evaluated the safety, optimal dose, and preliminary effectiveness of a new-approach Africanized honeybee (Apis mellifera) Antivenom (AAV) in a phase I/II, multicenter, non-randomized, single-arm clinical trial involving 20 participants with multiple stings. …”