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Ether induces proteotoxic stress, leading to a decrease in Trx protein and an increase in Hsp90 clients that are joint targets of Trx and Ubx.
Published 2024“…Representative images (10×) of untreated eggs (top) and eggs that were exposed to ether vapor for 2 h (bottom). <b>(F)</b> Representative images of Acridine Orange-stained <i>yw</i> embryos for the following cases: no treatment (up left), 5-min immersion in Citrasolv solution [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002629#pbio.3002629.ref046" target="_blank">46</a>] (up right), 5-min immersion in ether liquid (bottom right), and 1.5-h exposure to ether vapor (bottom left). …”
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Metronidazole-treated <i>Tg(Inta11:NTR)</i> larvae show defects in median fin fold mesenchyme migration, a reduction in median and pectoral fin fold size and a reduction in endoske...
Published 2018“…Inta11: NTR + MTZ larvae show a decrease in pectoral fin fold area at 72hpf, and 7dpf, as well as a reduction in endoskeletal disc size at 7dpf (J). …”
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A PPARα Promoter Variant Impairs ERR-Dependent Transactivation and Decreases Mortality after Acute Coronary Ischemia in Patients with Diabetes
Published 2010“…Electrophoretic mobility shift assays showed that the domain bound two known <em>PPARA</em> transcriptional activators, estrogen-related receptor (ERR)-α and -γ and that <em>PPARA</em> G bound with greater affinity than <em>PPARA</em> A (>2-fold; P<0.05). …”
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Discovery of a Colon-Targeted Azo Prodrug of Tofacitinib through the Establishment of Colon-Specific Delivery Systems Constructed by 5‑ASA–PABA–MAC and 5‑ASA–PABA–Diamine for the T...
Published 2022“…Specifically, compound <b>20g</b> displayed a 3.67-fold decrease of plasma AUC<sub>(tofacitinib, 0–∞)</sub> and a 9.61-fold increase of colonic AUC<sub>(tofacitinib, 0–12h)</sub>, compared with tofacitinib at a molar equivalent oral dose. …”
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Upcycling of Postconsumer Recyclate Polypropylene into Low Warping and High Toughness 3D Printable Filaments
Published 2025“…Incorporation of poly(butylene adipate-<i>co</i>-terephthalate) (PBAT) along with maleic anhydride grafted polypropylene (MAPP) in specific proportions led to a significant enhancement in mechanical properties, miscibility, crystallization behavior, and 3D printability. rPP/PBAT blends with 20 wt % PBAT and 10 wt % MAPP exhibited a 62-fold enhancement in elongation at break over rPP (from 1.88 to 118.29%) and a 72-fold increase in toughness (from 2 to 143.60 kJ/m<sup>3</sup>) with almost similar tensile strength. …”
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Upcycling of Postconsumer Recyclate Polypropylene into Low Warping and High Toughness 3D Printable Filaments
Published 2025“…Incorporation of poly(butylene adipate-<i>co</i>-terephthalate) (PBAT) along with maleic anhydride grafted polypropylene (MAPP) in specific proportions led to a significant enhancement in mechanical properties, miscibility, crystallization behavior, and 3D printability. rPP/PBAT blends with 20 wt % PBAT and 10 wt % MAPP exhibited a 62-fold enhancement in elongation at break over rPP (from 1.88 to 118.29%) and a 72-fold increase in toughness (from 2 to 143.60 kJ/m<sup>3</sup>) with almost similar tensile strength. …”
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<i>S.</i> Typhimurium-infected mice have tissue inflammation and thrombosis, increased hematopoiesis, and decreased splenic iron.
Published 2013“…The infected mouse had 11.5-fold more TER119<sup>med</sup> pro-erythroblasts and 5.5-fold more TER119<sup>high</sup> erythroblasts than the mock-infected mouse. …”
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Exposure to EtBr decreases mtRNA in rat striatal co-cultures, purified neuronal cultures, and astrocytes.
Published 2017“…<p>(A-C) Log2-fold decrease in mtRNA expression after EtBr treatment assayed with RNASeq, in (A) NECos, (B), pure neuronal cultures, and (C) astrocytes. …”
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Nef Decreases HIV-1 Sensitivity to Neutralizing Antibodies that Target the Membrane-proximal External Region of TMgp41
Published 2011“…Nef conferred as much as 50-fold resistance to 2F5 and 4E10, two potent neutralizing monoclonal antibodies (nAbs) that target the membrane proximal external region (MPER) of TMgp41. …”