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121
(R+S) and (R)-albuterol decrease NF-κB activity
Published 2011“…</p><p>Published online 14 Jan 2008</p><p>PMCID:PMC2253534.</p><p></p> A NF-κB luciferase reporter construct (pGL2) was cotransfected with a β-galactosidase (pGK) reporter construct by electroporation into T (EL4) cells. …”
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<i>Dmxl2</i> knockdown in INS-1E cells decreases glucose-induced insulin release.
Published 2014“…In the presence of various concentrations of glucose (5 and 20 mM), <i>Dmxl2</i>-siRNA–transfected cells displayed only a small increase in insulin release, at a glucose concentration of 20 mM only, whereas a 2- to 3-fold increase was observed with NT siRNA-transfected cells. …”
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(R)-albuterol decreases cytokine levels in activated murine splenocytes
Published 2011“…</p><p></p> (R)-albuterol (R), (S)-albuterol (S) or racemic albuterol (R + S) at a dose (10M) were added to murine splenocytes pre-activated with mitogens Concanavalin A (Con A, 5 μg/ml) and phorbol myristate acetate (PMA, 100 ng/ml) (CP), (Fig 3 A, B). …”
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MiR-129-5p levels were decreased in mouse depression models.
Published 2025“…<p><b>A.</b> Experimental schedule. All mice underwent behavioral tests following CRS treatment. …”
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TUDCA decreases ER stress in HOX neonatal rat lungs.
Published 2022“…<p>(<b>A</b>) The expression levels of ER stress markers (P-PERK 0.6±0.1-fold, p<0.001, n = 5; PERK 0.7±0.1-fold, p = 0.00364, n = 5; P-IRE1α 0.6±0.0-fold, p<0.001, n = 5; IRE1α 0.6±0.1-fold, p<0.001, n = 5; GRP78 0.8±0.1-fold, p<0.001, n = 5; cleaved ATF6 0.1±0.0-fold, p<0.001, n = 5; spliced XBP1 0.3±0.0-fold, p<0.001, n = 5; 2 males and 3 females) are all decreased while the N-glycosylated VEGFR2 is increased (3.5±0.2-fold, p<0.001, n = 5) in HOX neonatal lungs at P10 indicating TUDCA can attenuate hyperoxia-induced ER stress. …”
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128
Metabolites which (A) persistently increased and (B) persistently decreased with smoking.
Published 2014“…PIP = phosphatidylinositol phosphate, PS = phosphatidylserine, TG = triglyceride, DG = diglyceride, PE = phosphatidylethanolamine. Fold change ≥1.5; <i>p</i>-value≤0.05, x-axis = Log2 normalized abundance scale; Error bars represent 95% confidence; Significance values *≤0.05, **≤0.01, ***≤0.001.…”
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PI+ CD3+ T cells decrease at day 14 after IR while PI+ CD3- cells decrease at all time points.
Published 2024Subjects: -
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GSK343 treatment decreased <i>in vivo</i> tumor volume and growth.
Published 2021“…(A) Animals treated with GSK343 had significantly decreased fold change in tumor volumes compared to mice treated with vehicle. …”
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GFRα2 expression was dramatically decreased in Runx1 knockout mice.
Published 2013“…<p>ISH for GFRα2 in WT (<b><i>A</i></b>) and Runx1 knock out (<b><i>A<sup>/</sup></i></b>) mouse DRG showed significant reduction of GFRα2 in Runx1<sup>−/−</sup> ganglia. …”
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