Transcriptional collision hypothesis of <i>Ube3a</i> imprinting. by Linyan Meng (502323)

“…<p>Paternal <i>Ube3a</i> was found to be transcribed at a similar level as maternal <i>Ube3a</i> at the 5′ portion of the gene. …”

Data Sheet 1_Dependence on zopiclone: a case report.docx by Nana Guo (8595126)

“…</p>Case presentation<p>This case report describes a 43-year-old male patient who has been taking zopiclone for 12 years, with a maximum daily dose of 112.5 mg. …”

Aβ(25-35) aggregation on DOPC/DHA lipid bilayer. by Matilde Sublimi Saponetti (222515)

“…<p>(a-c) 5×2.2 µm² (1024×431px²) topographic AFM images of Aβ(25-35) aggregation on DOPC/DHA lipid bilayers. …”

Modulation of Cell Signaling Networks after CTLA4 Blockade in Patients with Metastatic Melanoma by Begoña Comin-Anduix (49217)

“…PBMC from tremelimumab-treated patients were characterized by increase in pp38, pSTAT1 and pSTAT3, and decrease in pLck, pERK1/2 and pSTAT5 levels. These changes were noted in CD4 and CD8 T lymphocytes but also in CD14 monocytes. …”

Efficacy and safety of lorcaserin in obesity: a systematic review and meta-analysis of randomized controlled trials by Awadhesh Kumar Singh (6174640)

“…</p> <p><b>Results</b>: The meta-analysis of four RCTs (N = 16,856) demonstrated a significant decrease in body weight (mean ∆ −3.076 Kg; 95% CI, −3.49 to −2.66; P < 0.00001), compared to placebo. …”

Disease course of Chronic Relapsing Inflammatory Optic Neuropathy (CRION) in a single care center by Luis Enrique MOLINA-CARRIÓN (12687286)

“…Infections, autoimmune diseases, and multiple sclerosis, among other conditions, were ruled out in all patients. Results: We analyzed 30 patients with CRION: 24 women and six men, with mean age of 42.8±10.2 years, median disease course of 7.9 years (5.29-13.1), and median number of attacks of 2 (IQR 2-4). …”

Image_1_Clinical Characteristics, Outcomes, and Risk Factors of Disease Severity in Patients With COVID-19 and With a History of Cerebrovascular Disease in Wuhan, China: A Retrospe... by Mengzhen Li (4709797)

“…Besides, patients with CVD, either with decreased lymphocyte count (OR 9.192, 95% CI, 1.410–59.902, P = 0.020) or increased blood urea nitrogen (OR 5.916, 95% CI, 1.072–32.641, P = 0.041), had a higher risk of developing severe events during hospitalization.…”

Transcriptome analysis of the thymus in rats administered cocaine. by Kana Unuma (283272)

Anthropic disturbances as the main driver of a semideciduous seasonal forest fragment in Minas Gerais by Tainá Mamede Cirne Silva (6152702)

“…We observed a density decrease and a basal area increase, which indicates the late successional stage of the analyzed tree community. …”

Behavioral profile of zebrafish larvae during a one-hour exposure to vehicle or PTZ. by Tatiana Afrikanova (288839)

Reactive oxygen species and nitric oxide signaling in bystander cells by Kishore Kumar Jella (3324954)

“…A decrease in cell viability was observed but no major change in cytotoxicity was found in HaCaT cells after treatment with irradiated cell conditioned media (0.005, 0.05 and 0.5 Gy ICCM). …”

Protective Effects of Dexrazoxane against Doxorubicin-Induced Cardiotoxicity: A Metabolomic Study by Yang QuanJun (3628550)

“…DOX treatment resulted in a steady increase in 5-hydroxylysine, 2-hydroxybutyrate, 2-oxoglutarate, 3-hydroxybutyrate, and decrease in glucose, glutamate, cysteine, acetone, methionine, asparate, isoleucine, and glycylproline.DZR treatment led to increase in lactate, 3-hydroxybutyrate, glutamate, alanine, and decrease in glucose, trimethylamine N-oxide and carnosine levels. …”

Carotid Sinus Massage in Syncope Evaluation: A Nonspecific and Dubious Diagnostic Method by Tan Chen Wu (5172170)

“…Symptoms were reported especially in those patients in whom CSM caused a SBP decrease to below 90 mmHg and/or asystole > 2.5 seconds, regardless of the pattern of response or the presence of previous syncope. …”

Carotid Sinus Massage in Syncope Evaluation: A Nonspecific and Dubious Diagnostic Method by Tan Chen Wu (5172170)

“…Symptoms were reported especially in those patients in whom CSM caused a SBP decrease to below 90 mmHg and/or asystole > 2.5 seconds, regardless of the pattern of response or the presence of previous syncope. …”

Table_1_The adverse impact of a gain in chromosome 1q on the prognosis of multiple myeloma treated with bortezomib-based regimens: A retrospective single-center study in China.pdf by Qingxiao Chen (13018167)

“…There were no statistical differences between PFS and OS when there were other chromosomal abnormalities, but there was a decreased tendency in PFS. LDH and +1q also had a synergistic adverse effect on survival.…”

Image_1_Mixed Hypertrophic and Dilated Phenotype of Cardiomyopathy in a Patient With Homozygous In-Frame Deletion in the MyBPC3 Gene Treated as Myocarditis for a Long Time.tiff by Olga Blagova (9418328)

Image_2_Mixed Hypertrophic and Dilated Phenotype of Cardiomyopathy in a Patient With Homozygous In-Frame Deletion in the MyBPC3 Gene Treated as Myocarditis for a Long Time.tiff by Olga Blagova (9418328)

Rad51 paralogs and the risk of unselected breast cancer: A case-control study by Peter Grešner (3533093)

“…<div><p>A case-control study was conducted in which we evaluated the association between genetic variability of DNA repair proteins belonging to the Rad51 family and breast cancer (BrC) risk. …”

Steady-state fluorescence studies provide additional support to the A region Model 3. by Sylvain Maenner (255271)

“…<p>In (A, B, and C), the binding sites of oligonucleotides P1 to P6 used in the FRET experiments are shown for the three 2-D structures of the A region corresponding to Models 1, 2, and 3. …”

A novel <i>adipose</i> loss-of-function mutant in <i>Drosophila</i> by Nicole A. Losurdo (18550883)

“…We found that despite a change in fat content in the body overall and a decrease in the number of larger (>5 µm) brain lipid droplets, there was no change in the brain lobe volume of mutant larvae. …”