Missense Variant in MAPK Inactivator <i>PTPN5</i> Is Associated with Decreased Severity of Post-Burn Hypertrophic Scarring by Ravi F. Sood (263139)

“…</p><p>Conclusions</p><p>We report <i>PTPN5</i> as a novel genetic locus associated with HTS severity. …”

Distribution of miRs with a greater than two fold-change. by Stephanie L. Samani (17896610)

Knockdown of ERα results in decrease in Mcl-1 mRNA expression. by Jennifer L. Schacter (589790)

Predicted steady state distribution of the percent of TDLs in a 1) control animal, 2) following increased in the average residence time of lymphocytes in the lung (20 fold, from 26 seconds to 9 minutes) due to, for example, inflammation in the lung; 3) following a decreased entrance rate of TDLs into lymph nodes and Peyer's patches (20 fold, e.g., by using anti CD62L antibody); 4) following a decreased exit rate of TDLs from lymph nodes and Peyer's patches (5 fold, e.g., using FTY720). by Vitaly V. Ganusov (142019)

Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2‑Aminoquinoline Inhibitors by Maris A. Cinelli (1309419)

“…We previously developed a class of membrane-permeable 2-aminoquinoline inhibitors and later rearranged the scaffold to decrease off-target binding. …”

PDGF-BB maintains Bcl2/Bax ratio and decreases caspase-3 activation induced by Tat and morphine. by Shaily Malik (226661)

“…(B) Densitometric analysis of the blots shown in (A). Tat and morphine together resulted in a significantly decreased ratio of Bcl2/Bax, indicating cell's progress towards apoptosis. …”

We cannot be “forever young,” but our children are: A multilevel intervention to sustain nursery school teachers’ resources and well-being during their long work life cycle by Ilaria Sottimano (5921096)

“…The third solution differed between groups: environmental redefinition (for group one); gymnastic and vocal hygiene (for group two). We hypothesized that the interventions improve teachers’ work abilities, increase well-being, and decrease stress and burnout. …”

Decreased β-cell mass in Hq mutant mice. by Fabienne T. Schulthess (13268705)

Maternal Hypoxia Decreases Capillary Supply and Increases Metabolic Inefficiency Leading to Divergence in Myocardial Oxygen Supply and Demand by David Hauton (341981)

“…Hearts of male offspring subjected to Maternal Hypoxia showed a 20% decrease in cardiac output (<i>P</i><0.05), despite recording a 2-fold increase in glucose oxidation (<i>P</i><0.01) and 2.5-fold increase (<i>P</i><0.01) in palmitate oxidation. …”

S1 Fig - by Asadollahi Parisa (8837432)

Subjects:

Macroscopic and histological assessment of colic tumor and inflammation in mice. by Asadollahi Parisa (8837432)

Subjects:

Decrease in vRNA in brain during antiretroviral therapy. by Sonny R. Elizaldi (9684796)

MK-STYX decreases RhoA activation. by Brittany M. Flowers (670483)

“…<p>(<b>A</b>) PC12 cells were transfected with pMT2 or pMT2-FLAG-MK-STYX-FLAG. 24 hr post-transfection cells were stimulated with 100 ng/ml NGF, and lysed at the indicated time points. …”

NR4A1 expression does not decrease after inhibition of p38, JNK and Src pathways. by Glenda Eger (636934)

Deletion of <i>sagA</i> alone results in a decrease in nasopharyngeal infection. by Blake A. Shannon (14197601)

UNC-62 RNAi decreases expression of collagen genes and increases expression of intestinal genes. by Eric L. Van Nostrand (30730)

“…The histogram indicates the distribution of genes by average fold-change upon <i>unc-62</i> RNAi. For 1699 genes with intestine-enriched expression <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-McGhee1" target="_blank">[23]</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-Pauli1" target="_blank">[33]</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-Spencer1" target="_blank">[34]</a> as well as the subset of 291 genes that also decrease expression with age <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-Budovskaya1" target="_blank">[10]</a>, we determined the average mean-centered fold-change from triplicate RNA-seq experiments of <i>unc-62</i> RNAi as compared to controls. …”

KCl treatment increases Elk1 SUMOylation and decreases katanin-p60 expression. by Ece Selçuk (436963)

<b>Glucagon Clearance is Decreased in Chronic Kidney Disease, but Preserved in Liver Cirrhosis</b> by Magnus F. G. Grøndahl (19160825)

NgR1 KO mice exhibited an increase in excitatory synapses and a decrease in inhibitory synapses, indicating an imbalance of synaptic transmission. by Jinwei Zhang (462455)

“…The inhibitory synaptic density of NgR1 mice showed a significant decrease when compared to WT mice (***P <  0.001). …”

Fold decrease in virulence gene expression of <i>Salmonella in vivo</i> and <i>in vitro</i>^a. by Xiaojian Yang (295141)

“…Values represent down-regulation (fold-decrease) of gene expression.</p>#<p>Value for each gene represents a significant difference (<i>P</i><0.05) between the treatment and control samples in the <i>in vitro</i> experiment. …”