Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

Subjects:

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

Subjects:

Decreased plasma H₂O₂ levels are associated with the pathogenesis leading to COVID-19 worsening and mortality by Liara Freitas Cavalcanti (14550766)

Overexpression of CCP5A and CCP5B induced flagellum length decrease and cell cycle defects. by Louise Basmaciyan (4576624)

Decreasing ShcA expression enhances TGF-β-induced Smad signaling. by Baby Periyanayaki Muthusamy (838234)

“…(D, E) Decreasing ShcA expression, upon transfection of ShcA siRNA (siShc-a for NMuMG cells, siShc-c for HaCaT cells) but not control siRNA, enhances Smad3-mediated transcription, quantified by luciferase expression from a 4xSBE-luciferase reporter, in NMuMG (D) and HaCaT (E) cells, in the absence of or in response to 0.8 ng/ml TGF-β, or treated with SB431542, for 6 h. …”

Decreased trigger factor association and increased DnaK association with ribosomes furthers protein homeostasis during Mg²⁺ starvation. by Carissa Chan (18310140)

Subjects:

A decrease in ACTH plasma concentration was found over time, while serum cortisol concentrations showed a delayed decrease. by Selma van Staveren (5909135)

5-FU induces a decrease in the total cell number in cultures of smooth muscle cells. by Marcelo de Carvalho Filgueiras (408321)

“…We found an initial reduction of 20% at 0.01 mM up to a reduction of 70% in 10 mM of 5-FU. …”

R848 mediated RANTES, but not TNF-α production, is significantly decreased in TRAM^−/− iBMDMs. by Enda Shevlin (628477)

Decreased echinocandin susceptibility in <i>Candida parapsilosis</i> causing candidemia and emergence of a pan-echinocandin resistant case in China by Yating Ning (11264310)

TGF-β1 had little effect on MMP-2, MMP-3 and MMP-14 expression, but decreased expression of MMP-16. by Youssef M. Farhat (295089)

PDGF-BB-induced NR4A1 expression is decreased after treatment with the NF-κB inhibitor BAY11-7082. by Glenda Eger (636934)

HVR1-swap compensatory E1/E2 substitutions typically decrease virus entry dependency on SR-BI. by Christina Holmboe Olesen (11154333)

In the absence of chloride, two-fold decrease in [Na⁺]_e shifted GLT-1a E_rev by −28 mV at both low and high glutamate concentrations. by Anatoli Y. Kabakov (729047)

“…<b>(C)</b> I-V curves of DHK sensitive currents obtained form <b>(B)</b> as a result of subtractions of averages of 2 I-V curves in presence of DHK from averages of 4 I-V curves in the absence of DHK at corresponding [Glu^-]_e and [Na⁺]_e. …”

Image_2_IL-1β enhances cell viability and decreases 5-FU sensitivity in novel colon cancer cell lines derived from African American patients.tif by Marzia Spagnardi (9330602)

“…When compared to Caucasian American (CA) patients, AAs also have reduced response to the first line standard of care chemotherapeutic agent 5-Fluorouracil (5-FU). Previously, we observed differential gene expression between the two populations, suggesting that colon tumors from AA patients display a decreased antitumor immune response and an increased expression of genes encoding proteins involved in inflammatory processes, such as Interleukin-1β (IL-1β). …”

MEK5 expression decreases ER signaling and confers endocrine resistance. by James W. Antoon (444010)

Decreased expression of HATL5 mRNA and protein in human carcinomas. by Gregory S. Miller (519005)

The expression of 5-hmC was decreased in ESCC tissues and cell lines. by Xuejiao Shi (1684186)

ETHE1-p.Arg163Gln and p.Arg163Trp are folded but have decreased stability. by Bárbara J. Henriques (627180)

Ethanol intoxication combined with burn injury decreases NFAT, Tbx21, Jun and Fos expressions in T cells. by Xiaoling Li (129705)