MTR_asym of tumor and NAWM and ΔMTR_asym in HGG. by Osamu Togao (470739)

“…<p>MTR_asym of tumor <b>(A)</b> was decreased with the saturation length in lower frequency range (<2 ppm), but was increased at 3.5 ppm. …”

Functional Characterization of AbeD, an RND-Type Membrane Transporter in Antimicrobial Resistance in <i>Acinetobacter baumannii</i> by Vijaya Bharathi Srinivasan (148478)

“…</p><p>Results</p><p>The <i>abeD</i> mutant displayed ~ 3.37 fold decreased survival and >5-fold reduced growth in hostile osmotic (0.25 M; NaCl) and oxidative (2.631 μM–6.574 μM; H₂O₂) stress conditions respectively. …”

Data_Sheet_1_Inflammatory biomarkers and delirium: a Mendelian randomization study.docx by Miao Yu (199182)

“…</p>Results<p>At the genome-wide significant level (P < 5e-8, r² < 0.001), genetically predicted sIL-6Rα was significantly associated with a decreased risk of delirium with less than three single-nucleotide polymorphisms (SNPs) in all three GWAS data sources (OR_Waldratio = 0.89, 95% CI: 0.79–0.96, P_Waldratio = 0.0016; OR_IVW = 0.88, 95% CI: 0.79–0.97, P_IVW = 0.008; OR_IVW = 0.88, 95% CI: 0.80–0.96, P_IVW = 0.004). …”

Inactivation of <i>Salmonella</i> Typhimurium and <i>Listeria monocytogenes</i> on ham with nonthermal atmospheric pressure plasma by Karolina Anna Lis (5278934)

“…The chosen plasma modes had a peak-to-peak voltage of 6.4 or 10 kV and a frequency of 2 and 10 kHz. …”

Marcksb plays a key role in the secretory pathway of zebrafish Bmp2b by Ding Ye (405963)

“…We then showed that Marcksb cell autonomously regulates the trafficking of Bmp2b from producing cell to the extracellular space and both the total and the extracellular Bmp2b was decreased in Marcksb-deficient embryos. …”

Statins Have No Additional Benefit for Pulmonary Hypertension: A Meta-Analysis of Randomized Controlled Trials by Lin Wang (11986)

“…<div><p>Objectives</p><p>We performed a meta-analysis to explore the effects of adding statins to standard treatment on adult patients of pulmonary hypertension (PH).…”

Preliminary molecular characterization of a proinflammatory and nociceptive molecule from the Echinometra lucunter spines extracts by Juliana Mozer Sciani (4626790)

A comprehensive meta-analysis on evidence of Mediterranean diet and cardiovascular disease: Are individual components equal? by Giuseppe Grosso (560782)

A Molecular Analysis Provides Novel Insights into Androgen Receptor Signalling in Breast Cancer by Jatin Mehta (703766)

“…Herein, we validated 10 genes as AR targets by studying the regulation of these genes in MDA-MB-453 cell line on stimulation by androgens like 5α-dihydrotestosterone (DHT), using RT-qPCR and ChIP assay. …”

Serum Metabolomics Reveals Serotonin as a Predictor of Severe Dengue in the Early Phase of Dengue Fever by Liang Cui (446525)

“…Herein, untargeted liquid-chromatography mass spectrometry metabolomics of serum from patients with dengue fever (DF) and dengue hemorrhagic fever (DHF) in the febrile phase (<96 h) was used to globally probe the serum metabolome to uncover early prognostic biomarkers of DHF. We identified 20 metabolites that are differentially enriched (<i>p</i><0.05, fold change >1.5) in the serum, among which are two products of tryptophan metabolism–serotonin and kynurenine. …”

An idealized view of the opportunity provided by a comparative and integrated oncology drug development path. by Ira Gordon (369869)

“…Factoring in additional costs for comparative studies with this approach of US$150,000 for studies conducted in the preclinical setting, US$250,000 for studies conducted before or during Phases I–II human trials and US$1 million for studies conducted before Phases II–III studies, the total cost of development is estimated at US$2.07 billion. The result may be a decrease in average clinical trial costs per approved drug from US$290 million to US$173 million <a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1000161#pmed.1000161-Adams1" target="_blank">[5]</a>.…”

The changing trends of <i>f</i>_<i>i</i>, <i>i</i> ∈ {1, 2, 3, 4} with <i>v</i> for the Moran process (first row) and the Wright-Fisher process (second row) when <i>u</i>... by Yanling Zhang (6561)

“…For all <i>r</i>, The curve of <i>f</i>₄ with <i>v</i> (fourth column) has an increasing trend with a small perturbation near <i>v</i> = 0.01. …”

Data_Sheet_1_Expression of vitamin D receptor, CYP24A1, and CYP27B1 in normal and inflamed canine pancreases.DOCX by Dohee Lee (432106)

“…This study showed that VDR expression decreased in inflamed pancreases and demonstrated CYP24A1 and CYP27B1 expression in the canine pancreas for the first time. …”

Data_Sheet_1_Therapeutic potential of robots for people who stutter: a preliminary study.DOCX by Yuichiro Yoshikawa (4512598)

“…The present study examines the feasibility of using a robot for speech therapy for PWS.</p>Methods<p>We prepared four settings (i.e., interviews with unfamiliar persons, interviews with unfamiliar communication robots, reading sentences aloud with a tandem robot that can utter the same words as a user by repeating the user’s voice after a short delay, and reading sentences aloud while being alone). …”

Data_Sheet_2_Therapeutic potential of robots for people who stutter: a preliminary study.DOCX by Yuichiro Yoshikawa (4512598)

“…The present study examines the feasibility of using a robot for speech therapy for PWS.</p>Methods<p>We prepared four settings (i.e., interviews with unfamiliar persons, interviews with unfamiliar communication robots, reading sentences aloud with a tandem robot that can utter the same words as a user by repeating the user’s voice after a short delay, and reading sentences aloud while being alone). …”

Core–Shell {Mn₇⊂(Mn,Cd)₁₂} Assembled from Core {Mn₇} Disc by Ling-Yu Guo (3068232)

“…HR-ESI-MS was even more precise by revealing three prominent molecular species, Mn₁₃Cd₆, Mn₁₄Cd₅ and Mn₁₅Cd₄, having a distribution of metals. …”

Table_1_Treatment of multiple sclerosis with rituximab: A Spanish multicenter experience.DOCX by Francisco Gascón-Giménez (12266840)

“…Mean EDSS had increased from 4.3 (SD: 1.9) to 4.8 (SD: 1.7) and almost half of the patients (41%) had worsened at least one point. After a median follow-up of 14.2 months (IQR: 6.5–27.2), ARR decreased by 85.7% (p < 0.001) and GEL by 82.9%, from 0.41 to 0.07 (p < 0.001). …”

Resource consumption of multi-substance users in the emergency room: A neglected patient group by Laurence Klenk (7434560)

“…<div><p>Background</p><p>Multi-substance use is accompanied by increased morbidity and mortality and responsible for a large number of emergency department (ED) consultations. …”

Table_1_Treatment of multiple sclerosis with rituximab: A Spanish multicenter experience.DOCX by Francisco Gascón-Giménez (12266840)

“…Mean EDSS had increased from 4.3 (SD: 1.9) to 4.8 (SD: 1.7) and almost half of the patients (41%) had worsened at least one point. After a median follow-up of 14.2 months (IQR: 6.5–27.2), ARR decreased by 85.7% (p < 0.001) and GEL by 82.9%, from 0.41 to 0.07 (p < 0.001). …”

Statistically significant mean gene expression differences between Aging and Development Periods (Multiple ANOVA results). by Christopher T. Primiani (588504)