Neonatal Maternal Deprivation Response and Developmental Changes in Gene Expression Revealed by Hypothalamic Gene Expression Profiling in Mice by Feng Ding (33360)

“…Unlike in adult rodents, expression levels of <em>Nanos2</em> and <em>Pdk4</em> were increased, and those of <em>Pgpep1</em>, <em>Ndp</em>, <em>Brms1l</em>, <em>Mett10d</em>, and <em>Snx1</em> were decreased after neonatal deprivation. In addition, we compared hypothalamic gene expression profiles at postnatal days 5 and 13 and observed significant developmental changes. …”

Analysis of synthetic SPS and CSL reporter activity under conditions of either GFP or Hairless overexpression. by Yi Kuang (1873354)

“…Box plots show the median, interquartile range, and 1.5 times interquartile range. Note, unlike the <i>12xCSL</i>_<i>17</i><i>-lacZ</i> reporter expression that was strongly decreased by Hairless overexpression (see <b><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009039#pgen.1009039.g006" target="_blank">Fig 6</a></b>), the <i>6xSPS</i>_<i>17</i><i>-lacZ</i> reporter with the same flanking sequences was not strongly impacted by ectopic Hairless. …”

Comparison of SCF-E and SCF Methods of Fitting PCR Amplification Curves. by Geoffrey K. Zath (7422305)

“…<p>Fluorescence intensities (Δ<i>R</i>_<i>N</i>) of bulk RT-qPCR amplification of six concentrations of IAV M gene RNA (<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1012257#ppat.1012257.s044" target="_blank">S2 Table</a>, 10-fold dilutions from 2.62 × 10⁴ to 2.62 × 10⁹ copies/μL) were measured at <i>N =</i> 1 to 40. …”

HI promotes FOXO3a dephosphorylation, which induces FOXO3a translocation into the nucleus and upregulates the expression of Bim and CC3. by Deyuan Li (769599)

“…However, p-FOXO3a levels decreased from 0.5 to 48 h and returned to baseline at 72 h after HI (A). …”

Sperm beat frequency and CA-activity in CA ^−/− mice. by Petra M. Wandernoth (149629)

“…<p><b>A</b>, Enzymatic activity of CA measured by mass spectrometry. Mean value of enzymatic activity of wild type sperm, is 5.26±0.34 U/ml, whereas sperm of CA IV^−/− mice show activity of 3.57±0.25 U/ml only (<i>n</i> = 6). …”

Heparinase treatment ablated daily oscillations in Aβ42 phagocytosis in macrophages. by Gretchen T. Clark (12071965)

“…<p>(A) A violin plot showing the phagocytosis of Aβ42 in the presence of a mixture of heparinases I, II, and III in logged mean fluorescence values plotted against PS and CT. …”

FIGURE 3 from Dodecafluoropentane Emulsion as a Radiosensitizer in Glioblastoma Multiforme by Jason D. Lickliter (16676097)

“…NMR T1 measurements represent mean ± SD for the 4 patients encompassing tumor or contralateral normal brain imaged at 1.5 T. …”

<i>nhr-62</i> modulates DR-induced fat metabolism. by Bree N. Heestand (437346)

“…*p<0.05, **p<0.01, ***p<0.001 by single factor ANOVA with Tukey test. Mean (Center Line) ± SD (Box) with bars representing an outlier coefficient of 1.5, or Mean±SEM.…”

Impact of culture medium on developmental competence and BCL-X protein expression of mouse embryos. by Xinyu Liu (34266)

“…Bars indicate mean ± s.e.m. Mann Whitney U-test was used for pairwise comparison. …”

Extracellular matrix-induced myelin sheet formation by oligodendrocytes requires Scribble. by Andrew A. Jarjour (343100)

“…While Scribble knockdown in oligodendrocytes cultured on PDL did not affect the proportion of cells with membrane sheets, the percentage of cells with membrane sheets (arrows in B) was significantly decreased on PDL-MG. Percent of O4-positive oligodendrocytes with myelin membrane sheets: non-targeting PDL = 13.6% ± 0.6%, non-targeting PDL-MG = 23.5% ± 0.8%, Scribble PDL-MG = 13.3% ± 0.9%. …”

Effects of Synthetic N-Terminal 17-Residue Peptide on the Δ2–17 MthK Channels by Mario Meng-Chiang Kuo (376172)

“…The time constant is 0.59 s (bottom panel, SDs are shown, <i>n</i> = 5).</p></div>…”

CD4⁺CD25⁺CCR4⁺ T cells in HAM/TSP produce lower levels of IL-4 and IL-10. by Yoshihisa Yamano (239101)

“…<p>A. Decreased mRNA expression levels of IL-4 and IL-10 in CD4⁺CD25⁺CCR4⁺ T cells from HAM/TSP patients. …”

EFFECTS OF SOIL WATER AVAILABILITY AND ORGANIC MATTER CONTENT ON FRUIT YIELD AND SEED OIL CONTENT OF CASTOR BEAN1 by Rogério D. de Lacerda (10383863)

“…Increased soil organic matter and available soil water for plants substantially increased productivity; however, seed oil content, mean 100-seed mass, mean 100-fruit mass, and seed:fruit ratio were affected by available soil water content alone. …”

Data_Sheet_1_Trajectories of (Bio)markers During the Development of Cognitive Frailty in the Doetinchem Cohort Study.pdf by M. Liset Rietman (6760496)

“…</p><p>Methods: The Doetinchem Cohort Study is a longitudinal population-based study that started in 1987–1991 in men and women aged 20–59 years, with follow-up examinations every 5 years. For the current analyses, we used data of 17 potentially relevant (bio)markers (e.g., body mass index (BMI), urea) from rounds 2 to 5 (1993–2012). …”

Data_Sheet_2_Trajectories of (Bio)markers During the Development of Cognitive Frailty in the Doetinchem Cohort Study.pdf by M. Liset Rietman (6760496)

“…</p><p>Methods: The Doetinchem Cohort Study is a longitudinal population-based study that started in 1987–1991 in men and women aged 20–59 years, with follow-up examinations every 5 years. For the current analyses, we used data of 17 potentially relevant (bio)markers (e.g., body mass index (BMI), urea) from rounds 2 to 5 (1993–2012). …”

The concentration dependence of toxicogenomic responses and the synergistic effects of low doses by Lixin Yang (41431)

“…</p><p></p> Embryos were exposed to decreasing concentrations of Cd (a, lane 1, 5 mg/l: lane 2, 2.5 mg/l; lane 3, 0.5 mg/l), or MeHg (b, lane 1, 60 μg/l; lane 2, 30 μg/l; lane 3, 6 μg/l) or TCDD (c, lane 1, 500 ng/l; lane 2, 250 ng/l; lane 3, 50 ng/l). …”

Perioperative Intravenous Acetaminophen Attenuates Lipid Peroxidation in Adults Undergoing Cardiopulmonary Bypass: A Randomized Clinical Trial by Frederic T. Billings IV (694958)

“…Acetaminophen concentrations measured 30 min into CPB and post-CPB were 11.9±0.6 μg/mL (78.9±3.9 μM) and 8.7±0.3 μg/mL (57.6±2.0 μM), respectively. Plasma free hemoglobin increased more than 15-fold during CPB, and haptoglobin decreased 73%, indicating hemolysis. …”

Involvement of SKN-1 in immunosenescence. by Diána Papp (169090)

“…(<b>C</b>) Pathogen resistance of young adult (1 day-old), 4 day-old and 9 day-old adult N2 and <i>skn-1(zu135)</i> mutant animals. <i>skn-1(zu135)</i> mutant worms exhibited significantly increased susceptibility to PA14 compared to N2 wild-type animals at all ages (p<0.0001). 1 day-old adult <i>skn-1(zu135)</i> worms show similar pathogen resistance to 4 day-old N2 worms (p = 0.1429) (middle graph). …”

DataSheet_1_Increased Risk of Cardiovascular Death in Breast Cancer Patients Without Chemotherapy or (and) Radiotherapy: A Large Population-Based Study.docx by Tianwang Guan (5766929)

“…</p>Results<p>The CVD risk was significantly higher (SMR = 2.196, 95% CI: 2.148–2.245, P<0.001) in breast cancer patients who did not receive CT or RT compared to the general population. …”

Mechanisms of Intestinal Serotonin Transporter (SERT) Upregulation by TGF-β1 Induced Non-Smad Pathways by Saad Nazir (2289973)

“…Treatment of Caco-2 cells with TGF-β1 (10 ng/ml, 60 min) stimulated SERT activity (~2 fold, P<0.005). …”