The DEG number and clustering analysis of DEG expression profile. by Xiaohua Du (1863520)

“…<p>(A-C) Volcano plots of the DEGs in the T1 vs control, T2 vs control and T2 vs T1 groups. Statistical significance (log₁₀ (<i>p</i>-value)) (Y-axis) has been plotted against log₂ (fold change) (X-axis). …”

Analysis of TCGA data reveals SRRM4 silencing in cancer across tissue types. by Sarah A. Head (6066398)

“…(F) The sum of the number of tissues with significantly up-regulated (positive) and down-regulated (negative) methylation in tumors, for each of the 202 SFs. (G) Fold change in median methylation (beta values) of the 2 SFs that consistently increase across all tumor types, with each point representing 1 tissue. …”

Simplified balance model of context-dependent effects of binding sites for transcriptional activators. by Kaiser J. Loell (17797684)

“…Stepwise addition of sites for a single TF first increase then decrease activity. …”

Heme-mediated stimulation of CXCL10 expression is TLR4 dependent. by Carmen M. Dickinson-Copeland (824626)

“…Results are expressed as fold change relative to housekeeping gene in treatment versus vehicle-treated cultures.…”

Fig 1 - by Simone Bach (9339740)

“…The genome harbors 7 protein genes whose mRNA expression levels (schematically shown below the genome, terminal dots indicating the 5’-cap) decrease from the first (NP) to the last (L) mRNA. …”

Modulation of Notch signaling affects axon outgrowth. by Ming Shi (78991)

“…(B–B'') Mis-expression of NICD results in a drastic decrease in the number of commissural axons crossing the midline. …”

Error-threshold exists in fitness landscapes with lethal mutants-0 by Nobuto Takeuchi (24907)

“…The notation and parameters are as follows (unless stated otherwise): The broken line is for = 0.05; the solid line is for = 0.5; the dotted line is for = 1.0; /= 0.99. Points (circles and plus signs) are calculated through the comparison of the first and second greatest eigen values of the model with back mutation [see "How high must lethality be to introduce an error-threshold" and Fig. 4(A) for details]. = 0.05 (the same as in Fig. 3) and = 0.99, unless stated otherwise. …”

Functional performance indicators associated with hypertension in older people by Emille Silva Santos (15475360)

Hydration behavior of asparagine: an approach using time domain reflectometry at low temperatures by Ravikant R. Karale (20481426)

“…<p>The dielectric behavior of Asparagine (C₄H₈N₂O₃) in water over the frequency range of 10 MHz to 30 GHz in the temperature region of 278.15–303.15 K in a step of 5 K has been carried out using time domain reflectometry (TDR) at various concentrations of asparagine. …”

Fig 1 - by M. Latorre (8840546)

“…<p>Fully developed, mechanobiologically equilibrated, axisymmetric dilatations of an initially cylindrical aortic segment caused by a mild (first column) or severe (second column) localized (via the respective parameter <i>ϑ</i>_{<i>central</i>} in Eq (<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008273#pcbi.1008273.e024" target="_blank">9</a>)) loss of elastic fiber integrity (first row, parameter <i>c</i>^<i>e</i>, mild 32% and severe 62% reduction), decrease in collagen cross-linking (second row, parameter , mild 9%, severe 23% reduction), loss of smooth muscle contractility (third row, parameter <i>T</i>_<i>max</i>, mild 60%, severe 100% reduction), compromised mechanosensing (fourth row, parameter <i>δ</i>, mild 7.5%, severe 18.5%, absolute), or compromised mechanoregulation (fifth row, parameter <i>G</i>^<i>c</i>, mild 0.4%, severe 1.2%, relative change), with the risk factors of hypertension (third column, 50% increase in blood pressure) and aortic aging (fourth column, uniform 30% loss of elastic fiber integrity) superimposed on the mild insults. …”

Image_2_Pharmacological Preconditioning Using Diazoxide Regulates Store-Operated Ca2 + Channels in Adult Rat Cardiomyocytes.JPEG by Raúl Sampieri (8297634)

“…Previously, we reported that pharmacological preconditioning (PPC) leads to a decrease in the amplitude of L-type calcium channel current in the heart. …”

Image_1_Liver-Specific Knockdown of Class IIa HDACs Has Limited Efficacy on Glucose Metabolism but Entails Severe Organ Side Effects in Mice.TIF by Nicole Ziegler (6893297)

“…For that, siRNAs selectively targeting HDAC4, 5 and 7 were selected and used to achieve a combinatorial knockdown of these three class IIa HDAC isoforms. …”

Macro-regions of Brazil. by Arnauld Kaufman (12731976)

“…Our results demonstrated a significant increase in the AAPC in Brazil’s less than 1-year-old age group and a decrease in children from 5 to 19 years old. …”

Data Sheet 1_Large scale atmospheric conditions favoring storm surges in the North and Baltic Seas and possible future changes.docx by Nils H. Schade (21676022)

“…Towards the end of the 21st century, the CMIP6 ensemble projects a significant increase in the frequency of westerly effective winds for Cuxhaven under the scenarios SSP3-7.0 and SSP5-8.5. …”

Table_1_Skin-to-blood pH shift triggers metabolome and proteome global remodelling in Staphylococcus epidermidis.XLSX by Luis Gafeira Gonçalves (13873508)

“…Here we studied the impact of pH conditions, mimicking the skin pH (5.5) and blood pH (7.4), in a S. epidermidis commensal strain by means of next-generation proteomics and ¹H NMR-based metabolomics. …”

Table_1_Liver-Specific Knockdown of Class IIa HDACs Has Limited Efficacy on Glucose Metabolism but Entails Severe Organ Side Effects in Mice.docx by Nicole Ziegler (6893297)

“…For that, siRNAs selectively targeting HDAC4, 5 and 7 were selected and used to achieve a combinatorial knockdown of these three class IIa HDAC isoforms. …”

Dissecting the Epstein–Barr virus entry pathway into astrocytes: unfolding the involvement of endosomal trafficking by Annu Rani (11223925)

“…</p> <p>EBV internalization decreased upon depletion of the lipid rafts.</p> <p>The dynamin protein plays a crucial role in EBV entry into astrocytes, and its depletion indicates a decrease in EBV entry.…”

Proteolysis of VWF strings at the surface of HUVEC by recombinant ADAMTS13 variants under flow. by Anton Letzer (8796422)

“…<p>(A) HUVEC were perfused at 5 dyne/cm² shear stress with 1 mM histamine and 100 μl of GPIbα-beads in HBRS buffer. …”

Image_2_Liver-Specific Knockdown of Class IIa HDACs Has Limited Efficacy on Glucose Metabolism but Entails Severe Organ Side Effects in Mice.TIF by Nicole Ziegler (6893297)

“…For that, siRNAs selectively targeting HDAC4, 5 and 7 were selected and used to achieve a combinatorial knockdown of these three class IIa HDAC isoforms. …”

ICD-10 version 2015. by Arnauld Kaufman (12731976)

“…Our results demonstrated a significant increase in the AAPC in Brazil’s less than 1-year-old age group and a decrease in children from 5 to 19 years old. …”