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Image_1_IL-1β enhances cell viability and decreases 5-FU sensitivity in novel colon cancer cell lines derived from African American patients.tif
Published 2022“…When compared to Caucasian American (CA) patients, AAs also have reduced response to the first line standard of care chemotherapeutic agent 5-Fluorouracil (5-FU). Previously, we observed differential gene expression between the two populations, suggesting that colon tumors from AA patients display a decreased antitumor immune response and an increased expression of genes encoding proteins involved in inflammatory processes, such as Interleukin-1β (IL-1β). …”
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MeV <i>M</i> mRNA quantification in cells treated with an inhibitor of RNA polymerase III.
Published 2023Subjects: -
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Homozygous deletion of <i>ERG251</i> leads to increased sensitivity to cell membrane and osmotic stress but decreased sensitivity to oxidative stress.
Published 2024“…Volcano plot for differentially expressed genes (log<sub>2</sub> fold change ≥ 1 or ≤-1 and adjusted <i>p</i>-value < 0.05) in the <i>erg251Δ/Δ</i> mutant compared to <i>ERG251/ERG251</i> in YPAD. …”
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717
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718
<i>S.</i> Typhimurium-infected mice have tissue inflammation and thrombosis, increased hematopoiesis, and decreased splenic iron.
Published 2013“…The infected mouse had 11.5-fold more TER119<sup>med</sup> pro-erythroblasts and 5.5-fold more TER119<sup>high</sup> erythroblasts than the mock-infected mouse. …”
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719
Image_2_A Shift in Myeloid Cell Phenotype via Down Regulation of Siglec-1 in Island Macrophages of Bone Marrow Is Associated With Decreased Late Erythroblasts Seen in Anemia of Cri...
Published 2019“…There were more (2.5-fold) EEBs and less LEBs (2.4-fold) per million TBM cells in B; with a corresponding decrease in Siglec-1 and Ly6G expressions in EBIMØ associated with EEB. …”
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720
Netrin-1 overexpression increases HCV RNA and specific infectivity of HCV virions in vitro whereas Netrin-1 depletion decreases HCV RNA and specific infectivity in vitro.
Published 2016“…Netrin-1 depletion impedes HCV. Huh7.5 cells were transfected with siRNAs, infected at a MOI of 0.1 24 h after seeding, and trypsinized at day five post-infection before a second siRNA transfection. …”