Showing 621 - 640 results of 103,497 for search '(( 2 fold decrease ) OR ( 5 ((((we decrease) OR (a decrease))) OR (nn decrease)) ))', query time: 1.60s Refine Results
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    Decreased Integrity, Content, and Increased Transcript Level of Mitochondrial DNA Are Associated with Keratoconus by Xiao-Dan Hao (215742)

    Published 2016
    “…The relative mtDNA content of KC corneas was significantly lower than that of normal corneas (<i>P</i> = 9.19×10<sup>−24</sup>), possibly due to decreased expression of the mitochondrial transcription factor A (<i>TFAM</i>) gene (<i>P</i> = 3.26×10<sup>−3</sup>). …”
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    Jump into a New Fold—A Homology Based Model for the ABCG2/BCRP Multidrug Transporter by Laura László (3221631)

    Published 2016
    “…Here we present a structural model of the ABCG2 homodimer based on this fold and detail the experimental results supporting this model. …”
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    S1 data_Hazen Main and Blister 2017 absolute diatom counts from Contrasting the ecological effects of decreasing ice cover versus accelerated glacial melt on the High Arctic's larg... by Neal Michelutti (688828)

    Published 2020
    “…Subfossil diatom assemblages in all cores show two major shifts over the past approximately 200 years including: (i) a proliferation of pioneering, benthic taxa at approximately 1900 CE from previously depauperate populations; and (ii) a rise in planktonic taxa beginning at approximately 1980 CE to present-day dominance. …”
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    Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

    Published 2022
    “…Compound <b>4f</b> exhibited potent EGFR inhibitory activity with an IC<sub>50</sub> value of 61 nM compared to that of Tamoxifen (IC<sub>50</sub> value of 69 nM), with EGFR inhibition of 83 and 84%, respectively, at a concentration of 10 μM. Interestingly, <b>4f</b> showed remarkable PI3K/AKT/mTOR inhibitory activity with 0.18-, 0.27-, and 0.39-fold decrease in their concentration (reduction in controls from 6.64, 45.39, and 86.39 ng/mL to 1.24, 12.35, and 34.36 ng/mL, respectively). …”
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    Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

    Published 2022
    “…Compound <b>4f</b> exhibited potent EGFR inhibitory activity with an IC<sub>50</sub> value of 61 nM compared to that of Tamoxifen (IC<sub>50</sub> value of 69 nM), with EGFR inhibition of 83 and 84%, respectively, at a concentration of 10 μM. Interestingly, <b>4f</b> showed remarkable PI3K/AKT/mTOR inhibitory activity with 0.18-, 0.27-, and 0.39-fold decrease in their concentration (reduction in controls from 6.64, 45.39, and 86.39 ng/mL to 1.24, 12.35, and 34.36 ng/mL, respectively). …”
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    Response of small airway tissues infected with EV-D94 and decreasing doses of EV-D68. by Ines Cordeiro Filipe (5849144)

    Published 2022
    “…<p>Tissues were infected with 1E7 RNA copies of EV-D94 (equivalent to 2,46E4 TCID50) and 1E7 RNA copies of EV-D68 (3,3E5 TCID50) as well as decreasing doses of the latter. …”