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OCA alone markedly decreases and combined with Gemcitabine or Cisplatin abrogates growth of iCCA xenografts.
Published 2019“…Treatment with Gemcitabine or Cisplatin alone decreased tumor volume to a higher (p < 0.05) extent than OCA alone. …”
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Decreased diaphragm muscle axonal branching distance, bifurcations and neuromuscular junctions in GAD67-deficient (−/−) E18.5 mice.
Published 2013“…D shows a significantly decreased medial and lateral bifurcation number (mean ± SEM) in GAD67-deficient mice compared to wild type (<i>n</i> = 10, **<i>P</i><0.01, ***<i>P</i><0.001, unpaired <i>t</i> test). …”
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Klf5 activates the transcription of the eIF5a gene through direct binding to its promoter.
Published 2020Subjects: -
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Image 5_G. vaginalis increases HSV-2 infection by decreasing vaginal barrier integrity and increasing inflammation in vivo.tif
Published 2024“…</p>Methods<p>Mice were inoculated with 10<sup>7</sup> CFU of the eubiotic bacteria Lactobacillus crispatus, the dysbiotic bacteria G. vaginalis, or PBS as a negative control every 48 h for ten days. On day ten, mice were inoculated with 10<sup>5</sup> PFU WT HSV-2 333 and survival, pathology, and viral titers were assessed. …”
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