B-Cell Dysregulation in Crohn's Disease Is Partially Restored with Infliximab Therapy by Wilhelmina M. C. Timmermans (3145413)

“…<div><p>Background</p><p>B-cell depletion can improve a variety of chronic inflammatory diseases, but does not appear beneficial for patients with Crohn’s disease.…”

Selection for Translational Robustness as a Function of Amino Acid Substitution Rate by Martin Willensdorfer (378401)

<i>hdc</i> depletion in progenitors triggers ROS production, but does not activate Foxo and insulin/mTOR. by Bayan Kharrat (19959505)

OsNF-YAs disturb the transcriptional activation of OsMYC2/3. by Xiaoxiang Tan (12542842)

The expression levels of <i>OsNF-YAs</i> genes in <i>OsNF-YAs</i> transgenic plants and the survival rates of the insect vectors on them. by Xiaoxiang Tan (12542842)

Monthly runoff observation values and variation in 4 hydrological stations in the YLRB. by Jintao Li (448681)

Thrombin modulates the expression of key regulators of the NO-cGMP pathway in a biphasic manner. by Katrin F. Nickel (421608)

“…<p>Left panel: Short time stimulation of HUVECs with thrombin (50 nM) increases (A) eNOS and (E) sGC beta 1 expression. Right panel: By contrast, chronic stimulation decreases (B) eNOS and (D) sGC alpha 1 expression, whereas (H) PDE5 expression is increased. …”

Fitted parameter values shown session by session, and at a subsession resolution in the initial and final sessions. by Noémi Éltető (14197656)

“…<p>The grey band on the bottom of each plot shows the sequence that participants practiced: the old sequence in sessions 1–8 (dark grey), the new sequence in session 9 (light grey), and both sequences alternately in session 10. Point distance in (a) and cell width in (b) are proportional to data bin size—we fitted the model to 5 epochs within sessions 1, 9, and 10 to assess potentially fast shifts. …”

Early correction of NMDAR function and NMDAR-dependent LTD by DCS treatment improves anxiolytic-like behavior, but not hypoactivity, in adult <i>Grin2b</i>^{<i>+/C456Y</i>}... by Wangyong Shin (6793040)

“…<i>n</i> = 9 cells from 4 mice for WT_V, 11 (5) for WT_D, 11 (5) for HT_V, 11 (3) for HT_D, *<i>P</i> < 0.05, two-way ANOVA with Tukey’s test. …”

Internal loading potential of phosphorus in reservoirs along a semiarid watershed by Diana Souza Moura (8743428)

“…Reservoirs R#5, R#1 and R#2 showed a tendency of decreasing total phosphorus (PT) as the sediment depth increased, probably indicating an increase of allochthonous phosphorus loading along time. …”

The chemical structure and the enzymatic and cellular activity of GSK360A. by Jin Zhou (90734)

Serum pentraxin 3 as a possible marker for mature cystic teratomas by Chiharu Ishida (2556577)

Distributions of rupture forces from MB231/HBME-60 and MB231/HPMEC adhesion measurements in four EC growing states. by Leike Xie (1317108)

Histogram of the extracted parameters. by Qiuyu Du (20760848)

“…Logistic regression (n = 93) showed that a less steep contrast gradient (decreasing by 10 Hounsfield unit/%) was associated with a reduction in odds of the following short-term adverse outcomes: 48.1% for intensive care unit admission (odds ratio [OR] = 0.519, 95% confidence interval [CI]: 0.306–0.804), 29.3% for oxygen therapy >24 hours (OR = 0.707, 95% CI: 0.496–0.976), 60.6% for reperfusion therapy (OR = 0.394, 95% CI: 0.178–0.682), 57.5% for vasopressor therapy (OR = 0.425, 95% CI: 0.194–0.741), and 50.2% for PE-related death (OR = 0.498, 95% CI: 0.246–0.915). …”

10 μM βE2 pretreatment for 0.5 hrs protected primary cultured SD rat retinal cells from apoptosis induced by 100 μM H₂O₂ treatment for 24 hrs. by Yan Feng (128912)

“…<p>The PI3K/Akt pathway mediated this process, but the alteration in [Ca²⁺]_i was undetectable. A: The Annexin V/Propidium Iodide staining apoptosis assay; B: Quantitative data of A; C and D: Cell viability and [Ca²⁺]_i quantitative data; 10 μM βE2 pretreatment for 0.5 hrs significantly restored the decrease in cell viability and apoptosis, which was significantly inhibited by 10 μM LY (B, C), but the [Ca²⁺]_i was not significantly altered in all treated groups (D); E: Western blot results, 10 μM βE2 pretreatment for 0.5 hrs promoted p-Akt level, which was inhibited by 10 μM LY pretreatment for 0.5 hrs before βE2 and H₂O₂ co-treatment. …”

Rapid RpoS recovery from phosphate and glucose starvation requires Crl. by Sophie Bouillet (18137403)

Effect of CPA treatment on ERG recordings (I): a-wave and b-wave. by Manuel Soliño (5410001)

“…A significant higher amplitude of of a-wave was detected in CPA treated eyes compared to CTL eyes (14.07 ± 3.56 μV vs 7.14 ± O.63, unpaired Student´s t-test; p<0.05; n = 5), *p< 0.05. …”

Kaplan Meier curves of OS and PFS according to RT and/or CRT response. by Huriye Senay Kiziltan (22298378)

Oxidative stress may play a role in nuclear inclusion formation. by Priyanka Thakur (578653)

“…(<b>B</b>) Quantification revealed a significant difference in 4-HNE levels in HBsAg-Tg mice treated with (n = 5) and without NAC (n = 5). …”

Table_1_Dysregulation of Principal Circulating miRNAs in Non-human Primates Following Ischemic Stroke.XLSX by Jian Chen (15340)

“…For example, mml-miR-191-5p, miR-421, miR-409-5p, and let-7g-5p were found to be significantly overexpressed, whereas mml-miR-128a-5p_R − 2, miR-431_R − 1, and let-7g-3p_1ss22CT were significantly downregulated. …”