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point decrease » point increase (Expand Search)
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Validation of primary screen hits reveals compounds that recapitulate increased spheroid size (swell) or decreased MUC5AC in the lumen.
Published 2023“…Compounds that appeared to cause toxicity were identified by observing a significant decrease in spheroid counts in the swell readout or a significant decrease in the total nuclear intensity of the MUC5AC ratio readout. …”
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Effect of the universal nuclease on various concentration of infectious intact FCoV viruses.
Published 2023Subjects: -
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<i>Ex vivo</i> deletion of <i>sirt1</i> decreases expression of RUNX2 downstream targets.
Published 2017“…<b>C)</b> While SIRT1 knockout osteoblasts (Cre) express comparable amounts of Runx2, they show a near two-fold reduction in the expression of the Runx2 downstream target, <u>Osterix</u> (Osx). …”
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Retinoic acid alleviates decreases of phospho-Akt and phospho-Bad expression caused by MCAO damage.
Published 2024“…Molecular weight (kDa) are depicted at right. Data (<i>n</i> = 5) are represented as mean ± S.E.M. *<i>p</i> < 0.001, **<i>p</i> < 0.01 vs. vehicle + sham animals, #<i>p</i> < 0.01 vs. vehicle + MCAO animals.…”