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Proinflammatory signaling pathways were decreased in Ad26.COV2.S vaccinated compared to sham unvaccinated hamsters.
Published 2022“…<p><b>(A)</b> Boxplots of SARS-CoV-2 transcripts normalized read counts across all animals, vaccinated hamsters are shown in blue and pink, and sham animals in green. …”
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Mean decrease in accuracy (MDA) of top 15 urine metabolites.
Published 2020“…Urine metabolites with a mean decrease in accuracy ≥ 0.004 in at least one post-treatment time point (2–5) were considered for inclusion in the predictive model.…”
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PDGF-BB maintains Bcl2/Bax ratio and decreases caspase-3 activation induced by Tat and morphine.
Published 2011“…(B) Densitometric analysis of the blots shown in (A). Tat and morphine together resulted in a significantly decreased ratio of Bcl2/Bax, indicating cell's progress towards apoptosis. …”