Three unrelated and unexpected amino acids determine the susceptibility of the interface cysteine to a sulfhydryl reagent in the triosephosphate isomerases of two trypanosomes by Selma Díaz-Mazariegos (224283)

“…We demonstrate that a seventy-fold difference in the reactivity of an interface cysteine to the sulfhydryl reagent methylmethane sulfonate in these two enzymes depends on three amino acids located far away from this critical residue and which could not have been predicted using other current methods. …”

Supplementary Material for: Effects of a DPP4 Inhibitor on Progression of NASH-related HCC and the p62/ Keap1/Nrf2-Pentose Phosphate Pathway in a Mouse Model by Kawaguchi T. (5713799)

“…Metabolome analysis revealed that DPP4i significantly increased 6-phosphogluconic acid and ribose 5-phosphate levels and decreased the AMP-to-adenine and GMP-to-guanine ratios (AMP-to-adenine ratio 0.7 ± 0.2 vs. 2.0 ± 1.2, <i>p</i> < 0.01; GMP-to-guanine ratio 0.6 ± 0.3 vs. 1.5 ± 0.7, <i>p</i> < 0.01). …”

DataSheet_1_Data-Driven Analysis of COVID-19 Reveals Persistent Immune Abnormalities in Convalescent Severe Individuals.docx by Jackwee Lim (218815)

“…Strikingly, survivors of severe COVID-19 had decreased proportions of NKT and Vδ2 T cells, and increased proportions of low-density neutrophils, IgA+/CD86+/CD123+ non-classical monocytes and hyperactivated HLADR+CD38+ CD8+ T cells, and elevated levels of pro-inflammatory cytokines such as hepatocyte growth factor and vascular endothelial growth factor A, long after virus clearance. …”

Improvement of saline soils with Vicia sativa L. from a semiarid region by Marcos Afonso Lastiri Hernández (5667116)

“…Analysis of variance was performed to examine the effects of salinity on each of the evaluated variables; Tukey’s test was used to detect differences between the mean values of the variables per treatment. In a greenhouse experiment, the species V. sativa is confirmed to be tolerant to a moderately saline level. …”

A DNA nanodevice for mapping sodium at single organelle resolution - raw data by Junyi Zou (16821438)

“…By measuring Na⁺ at single endosome resolution in mammalian cells and in <i>C. elegans</i>, we discover that lumenal<i> </i>Na⁺ levels in each stage of the endolysosomal pathway exceed cytosolic levels and decrease as endosomes mature. Further, we find that lysosomal Na⁺ levels in nematodes are modulated by the Na⁺/H⁺ exchanger NHX-5 in response to salt stress. …”

Schistosoma mansoni associated glomerulopathy with IgA mesangial deposits: case report by Fabiana Oliveira Gonçalves (10467328)

“…Method: It was reported a case of a 36 years old patient, brown, with classical sintoms of nephrotic syndrome (proteinuria > 3.5 g/24h, hypoalbuminemia and hypercholesterolemia), however with hepatosplenic schistosomiasis history 7 years ago and portal hypertension. …”

Length Scale of the Dendritic Array Tailoring Strength of a 5052 Aluminum Alloy by Cínthia Toshimi Ogata (6046400)

“…The 5052 alloys containing higher Mg content may induce a decrease in λ2 for a certain growth velocity. …”

DataSheet_1_Xylanase VmXyl2 is involved in the pathogenicity of Valsa mali by regulating xylanase activity and inducing cell necrosis.docx by Xinyue Cui (6291014)

“…VmXyl2 has highly elevated transcript levels during the infection process of V. mali, with 15.02-fold increase. …”

The long tail XBP1 mRNA escapes translational repression during the acute UPR. by Mohammed R. Alzahrani (13229154)

Data_Sheet_1_Efficacy and feasibility of a 12-week Tai Chi training for the prophylaxis of episodic migraine in Hong Kong Chinese women: A randomized controlled trial.docx by Yao Jie Xie (10073843)

“…Women aged 18 to 65 years and diagnosed with episodic migraine were randomized to either Tai Chi group (TC group) or the waiting list control group. A modified 33-short form Yang-style Tai Chi training with 1 h per day, 5 days per week for 12 weeks was implemented in the TC group, with a 12-week follow up period. …”

<i>In vivo</i> effect of NIR-PIT for MDAMB231 tumor. by Tadanobu Nagaya (789144)

“…The tumor treated by NIR-PIT showed decreasing IR700 fluorescence after NIR-PIT. (C) Tumor growth was significantly inhibited in the PIT treatment groups with cet-IR700 (n = 10–13, *<i>p</i> < 0.05 vs i.v. group, **<i>p</i> < 0.01 vs control and light only group, Bonferroni’s test with ANOVA). …”

Hyperacetylation of PS1 and BACE1 was suppressed by p300 specific inhibitor curcumin in N2a/APPswe cells. by Xi Lu (288663)

“…<p>(A) the p300 protein was markedly decreased in N2a/APPswe cells after being treated with curcumin; (B) curcumin dramatically reduced the enhancement effect of p300 in N2a/APPswe cells by immunocytochemistry, Magnification 400-fold, Scale bar: 50 µm; (C) curcumin treatment significantly suppressed the HATs activity in N2a/APPswe cells; (D) the Ac-H3 to PS1 and BACE1 promoter regions was much lower in N2a/APPswe cells after being treated with curcumin compared to DMSO (placebo) group; (E) the cellular Ac-H3 in N2a/APPswe cells was statistically significantly decreased after curcumin treatment; (F) N2a/APPswe cells after being treated with curcumin showed reduced binding of p300 to PS1 and BACE1 in N2a/APPswe cells. …”

Presentation_1_Enhanced Reproductive Thermotolerance of the Tomato high pigment 2 Mutant Is Associated With Increased Accumulation of Flavonols in Pollen.pptx by Nicholas Rutley (5952422)

“…Indeed, pollen from two alleles of the hp2 mutant was found to have flavonols levels increased by 18 and 280% compared with wild-type (WT) under moderate chronic heat stress (MCHS) conditions. …”

STOX1A induces changes in several major cell cycle regulatory genes. by Daan van Abel (214754)

“…<p>(A) The effect of stable STOX1A overexpression in the SH-SY5Y neuroblastoma cell line on four major mammalian cell cycle regulatory genes was determined with quantitative RT-PCR showing a mean 1,4 fold (mean ΔΔCt is −0,49) and mean 1,72 fold (mean ΔΔCt is −0,78) increased mRNA expression for CCNA2 and CCNB1, respectively, and a mean 1,22 fold (mean ΔΔCt is −0,29) decreased mRNA expression for CCNC in STOX1A stably transfected cell compared to their negative controls. …”

<i>In vivo</i> effect of NIR-PIT for MDAMB468 tumor (one shot NIR-PIT). by Tadanobu Nagaya (789144)

“…<p>(A) NIR-PIT regimen. Fluorescence images were obtained at each time point as indicated. …”

Data_Sheet_1_Post-COVID-19 condition: systemic inflammation and low functional exercise capacity.pdf by Gabriela Salim de Castro (12022307)

<i>In vivo</i> fluorescence imaging of MDAMB231 and MDAMB468 tumors. by Tadanobu Nagaya (789144)

Image_2_Unusually Warm Summer Temperatures Exacerbate Population and Plant Level Response of Posidonia oceanica to Anthropogenic Nutrient Stress.TIF by Stephanie B. Helber (5429045)

Table_2_Unusually Warm Summer Temperatures Exacerbate Population and Plant Level Response of Posidonia oceanica to Anthropogenic Nutrient Stress.docx by Stephanie B. Helber (5429045)

Cnot4 heterozygosity confers resistance to high fat diet-induced obesity. by Tomokazu Yamaguchi (8284989)