Discovery of 2‑Ethoxy-5-isobutyramido‑<i>N</i>‑1-substituted Benzamide Derivatives as Selective Kv2.1 Inhibitors with In Vivo Neuroprotective Effects by Jie Zhou (28945)

“…Among them, compound <b>80</b> (IC₅₀ = 0.07 μM, selectivity >130 fold over other K⁺, Na⁺, and Ca²⁺ ion channels) was able to decrease the apoptosis of HEK293/Kv2.1 cells induced by H₂O₂. …”

Discovery of 2‑Ethoxy-5-isobutyramido‑<i>N</i>‑1-substituted Benzamide Derivatives as Selective Kv2.1 Inhibitors with In Vivo Neuroprotective Effects by Jie Zhou (28945)

“…Among them, compound <b>80</b> (IC₅₀ = 0.07 μM, selectivity >130 fold over other K⁺, Na⁺, and Ca²⁺ ion channels) was able to decrease the apoptosis of HEK293/Kv2.1 cells induced by H₂O₂. …”

Discovery of 2‑Ethoxy-5-isobutyramido‑<i>N</i>‑1-substituted Benzamide Derivatives as Selective Kv2.1 Inhibitors with In Vivo Neuroprotective Effects by Jie Zhou (28945)

“…Among them, compound <b>80</b> (IC₅₀ = 0.07 μM, selectivity >130 fold over other K⁺, Na⁺, and Ca²⁺ ion channels) was able to decrease the apoptosis of HEK293/Kv2.1 cells induced by H₂O₂. …”

Data_Sheet_1_Effectiveness of non-pharmaceutical interventions in nine fields of activity to decrease SARS-CoV-2 transmission (Spain, September 2020–May 2021).PDF by Inés Barbeito (5864351)

“…</p>Methods<p>A stringency index (0–1) was created for each Spanish province (n = 50) daily. …”

S6 Fig - by Yang Jiang (46459)

Subjects:

Ni causes a decrease in membrane sterols in A549 lung epithelial cells. by Amber R. Matha (19681603)

According to the initial retention time of individuals, the dynamics of dispersion of groups of 40 woodlice (a) and the time necessary to disperse 50% of the population introduced... by Pierre Broly (228993)

According to number of woodlice initially introduced, the dynamics of the dispersion of groups held for 300 s (a) and the time necessary to disperse 50% of the population introduce... by Pierre Broly (228993)

Knockdown of MRN complex decreases HBV cccDNA level. by Kaitao Zhao (3617825)

Knockdown of MRN complex decreases HBV cccDNA level. by Kaitao Zhao (3617825)

Effects of siRNA TMPRSS2-ERG on ERG protein expression and cell viability. by Giorgia Urbinati (554921)

“…<p>VCaP cells were transfected for 24h, 48h and 72h with 50 nM of siRNAs TMPRSS2-ERG III (1, 2, 3), siRNAs TMPRSS2-ERG IV (1, 2), siRNA against ERG wild type or siRNA Control. …”

Masson’s trichrome staining. by Sergiy G. Gychka (13175728)

Subjects:

Immunohistochemistry of the Kv11.1 channels in the placental arteries of women who gave birth without or with COVID-19 during pregnancy. by Sergiy G. Gychka (13175728)

Subjects:

Immunohistochemistry of α-smooth muscle actin in the placental arteries of women who gave birth without or with COVID-19 during pregnancy. by Sergiy G. Gychka (13175728)

Subjects:

Characteristics of samples used in this study (means ± SD). by Sergiy G. Gychka (13175728)

Subjects:

Vascular wall thickening in the placentas of women who contracted COVID-19 during pregnancy. by Sergiy G. Gychka (13175728)

Subjects:

Morphometric analysis of the placental arterial wall thickness in women who gave birth without or with COVID-19. by Sergiy G. Gychka (13175728)

Subjects:

Three-, bi- and mono-functional Vγ9Vδ2 T-cell subsets decrease in HIV+ patients. by Rita Casetti (608635)

Datasheet1_Acquired von Willebrand syndrome (AVWS) type 2, characterized by decreased high molecular weight multimers, is common in children with severe pulmonary hypertension (PH)... by Ivonne Wieland (14112981)

“…Hemostatic complications were observed in 4 of 12 (33%) patients with VWS and 3 of 6 (50%) patients without diagnostics and therapy.</p>Conclusion<p>For children with moderate to severe PH, we recommend systematic analysis of von Willebrand variables, including multimer analysis, PFA-100 and platelet function testing. …”

Barbie’s ankle equinus measured at 50 degrees as equnius posture (a) and flat foot posture measured at 0 degrees (b), with a handheld goniometer. by Cylie Williams (3446018)