Effect of replacing beef fat with safflower oil on physicochemical, nutritional and oxidative stability characteristics of wieners by Emel KAYNAKCI (10463779)

“…Incorporation of SO increased CIE L* and b* values, whereas it caused a decrease in CIE a* values of wieners (P < 0.05). …”

Label-free real-time multi-parametric monitoring enables high content analysis. by Heinz-Georg Jahnke (122745)

“…The effect on the APD was determined for one hour after doxorubicin application and revealed a concentration dependent response with an EC₅₀ value of 17 µM (n  = 3 hCMC), (B) The impedance analysis revealed a concentration- and time-dependent decrease where IC₅₀ values could be determined for each time point (n  = 5 hCMC). …”

Changes in monosome and polysome association of cellular mRNAs following VSV infection. by William J. Neidermyer Jr. (6866672)

“…Genes outside the 95% confidence interval are denoted by blue (increased) or green (decreased) dots. (D) The log₂ fold changes in association at 6 hpi as presented in C. …”

Kinases are recruited to the signaling complex by alternative N-t localization domains. by Paloma M. Sato (672126)

“…In most cases, mutations that disrupt specific recruitment interactions decrease pathway activation between 40%–50%. MUT Ste20[N]-Ste50[C] might still localize to the signaling complex, as Ste50's RA domain binds Cdc42 independently of Ste20's PBD domain <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1002012#pbio.1002012-Truckses1" target="_blank">[53]</a>. …”

CRT silencing improved FZD-induced injury of mitochondria and cardiomyocytes. by Ming Zhang (9736)

“…When transfected NRCMs were stimulated with 50 µM FZD for 24 h, real-time PCR revealed that CRT silencing significantly inhibited the decrease of MnSOD mRNA expression (E), and western blot was used to determine the protein levels of CRT, phosphorylated and total STAT3, and MnSOD in the whole cell lysates. β-actin was used as a loading control. …”

Map of thermal risk variation, based on the response of lizards to dehydration for <i>Loxopholis percarinatum</i> across the amazon basin. by Agustín Camacho (331354)

“…D represents thermal risk after a 50% decrease in rainfall, E shows risk after a decrease of 20% in tree cover, and F shows the risk for lizards with VTmax = 28.8°C, The median VTmax for <i>L</i>. …”

Use of GPCR-HIT to show effect of AT₁ receptor activation on CCR2/Gα_i1 proximity. by Mohammed Akli Ayoub (176430)

“…It has been observed previously [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0119803#pone.0119803.ref039" target="_blank">39</a>,<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0119803#pone.0119803.ref041" target="_blank">41</a>,<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0119803#pone.0119803.ref042" target="_blank">42</a>,<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0119803#pone.0119803.ref044" target="_blank">44</a>] that the BRET signal can increase or decrease as a consequence of the ligand-induced conformational change associated with Gα_i1 protein activation (A). …”

Table 1_Role of seed priming using natural biostimulants in reducing salt stress effects by reshaping physio-biochemical and antioxidant defense systems in glycine max seedlings.do... by Mostafa M. Rady (14004633)

“…<p>Abiotic stress significantly damages crops, reducing global yields by over 50%. Among these challenges, salt stress poses a critical constraint that severely affects the growth, productivity, and quality of soybeans in various regions worldwide. …”

Changes in human intervertebral disc biochemical composition and bony end plates between middle and old age by Delio Eulalio Martins (5759282)

“…</p><p>Results</p><p>The old-aged group showed a decrease in content of sulphated and non-sulphated glycosaminoglycans relative to middle-aged and there were also alterations in the proportion of GAG disaccharides and a decrease of collagen fiber size. …”

Donor and Geometry Optimization: Fresh Perspectives for the Design of Polyoxometalate Charge Transfer Chromophores by Bethany R. Hood (20396768)

Hormone addition results in chromatin changes at individual GR-regulated genes. by Chuong D. Pham (111374)

“…We calculate that a nucleosome/bare ratio of 1.0 corresponds to ∼50% nucleosome occupancy, while a value of 2.1 corresponds to 100% occupancy (e.g. a nucleosome covering a given location on all gene copies). …”

Brivanib inhibits liver fibrosis induced by thioacetamide. by Ikuo Nakamura (548298)

“…(B) The number of bands of bridging fibrosis per high power field were counted in images obtained at 100× magnification after Sirius red staining. There was a significant decrease in the number of bands in both the 25 mg/kg and 50 mg/kg brivanib groups, compared to placebo. …”

Collagen XVI overexpression leads to an increase of ILK/kindlin-1 interaction. by Konstanze B. Bedal (513309)

“…<p>(<b>A</b>) Proximity ligation assay for the analysis of ILK/kindlin-1 interaction in COLXVI and mock control cells (scale bar equals 50 µm). …”

Toll-like receptor 3 regulates Zika virus infection and associated host inflammatory response in primary human astrocytes by Chet Raj Ojha (4258624)

“…Infection by PRVABC59 elicited the highest release of inflammatory molecules, with a 8-fold increase in the release of RANTES, 10-fold increase in secretion of IP-10 secretion and a 12-fold increase in IFN-β secretion when compared to un-infected human astrocytes. …”

The effect of dopamine on Δψ_m and [Ca²⁺]_c in midbrain neurons and astrocytes. by Sonia Gandhi (49260)

“…Furthermore this increase in [Ca²⁺]_c is associated with a reduction in ΔΨ_m. Application of 50 mM KCl induces a further rise in [Ca²⁺]_c and profound mitochondrial depolarisation. …”

DataSheet1_Dynamics of trace and rare earth elements during long-term (over 4 years) decomposition in Scots pine and Norway spruce forest stands, Southern Sweden.docx by Mukesh K. Gautam (16554267)

“…The changes in concentration and amount of trace elements resulted in two main types of dynamics: 1) both concentration and amount increased for Fe, Al, Ti, Cu, Mo, V, Zr, Sb, As, Cs, Pb, Th, and U; 2) concentration increased but amount decreased for Ni, Zn, Li, and Sr. …”

Poly Q aggregates alter the expressions of miR-125b, miR-150, p53, RelA/NFkB and miR-146a. by Jayeeta Ghose (207861)

“…(<b>C</b>) Similarly, miR-146a expression (n = 4, p = 0.011), miR-125b expression (n = 2, p = 0.048) and miR-150 expressions (n = 2, p = 0.039) were decreased significantly in ST<i>Hdh^Q7/Hdh^Q7</i> cells 48 hours post transfection with 83Q DsRed compared to ST<i>Hdh^Q7/Hdh^Q7</i> cells 48 hours post transfection with empty vector DsRed. miR-17-5p was used as endogenous control to calculate fold change in each case; (<b>D</b>) Immunoblotting with cell extracts prepared from HYPK-GFP transfected ST<i>Hdh^Q7/Hdh^Q7</i> cells and Hsp70-GFP transfected ST<i>Hdh^Q7/Hdh^Q7</i> cells showed increase in the expression of HYPK (in panel I probed by anti-HYPK antibody) and Hsp70 (in panel II probed by anti-GFP antibody) respectively compared to those obtained in ST<i>Hdh^Q7/Hdh^Q7</i> cells transfected with empty vector GFP-C1.…”

Intron Retention in mRNA Encoding Ancillary Subunit of Insect Voltage-Gated Sodium Channel Modulates Channel Expression, Gating Regulation and Drug Sensitivity by Céline M. Bourdin (446325)

“…We investigated the gating and pharmacological properties of the <i>Drosophila</i> Na_v channel variant (DmNa_v1-1) co-expressed with DmTEH1, PaTEH1A, PaTEH1B or a truncated mutant PaTEH1Δ(270-280) in <i>Xenopus</i> oocytes. PaTEH1B caused a 2.2-fold current density decrease, concomitant with an equivalent α-subunit incorporation decrease in the plasma membrane, compared to PaTEH1A and PaTEH1Δ(270-280). …”

Excretion in acoelomorphs. by Carmen Andrikou (7053542)

“…Error bars indicate minimum and maximum of the biological replicates (averaged technical replicates). A 1-fold change represents no change; ≥2 indicates significantly increased expression level; ≤0.5 indicates significantly decreased expression level (red labels). …”

Total nuclease activity, Dnase1 and Dnase1l1-3 expression in kidneys from BALB/c and (NZBxNZW)F1 mice. by Svetlana N. Zykova (134165)

“…(<i>A</i>) Kidney lysates (black) or sera (grey), in which total protein was measured, and protein content of the samples normalized using BCA assay (Pierce), were applied onto 1% agarose gels containing calf thymus DNA and ethidium bromide in a CaCl₂- and MgCl₂- containing buffer, pH 7.6, and incubated in a humidified chamber at 37°C for 24 hours. …”