Search alternatives:
point decrease » point increase (Expand Search)
fold decrease » fold increase (Expand Search), fold increased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
2 mean » _ mean (Expand Search), a mean (Expand Search), i mean (Expand Search)
point decrease » point increase (Expand Search)
fold decrease » fold increase (Expand Search), fold increased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
2 mean » _ mean (Expand Search), a mean (Expand Search), i mean (Expand Search)
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Alternative bounded and monotonically decreasing functions do not accurately fit the bias in the naïve SI.
Published 2022“…The BAE method more accurately fits the data than an exponential fit (matched-pairs two-sided t-test<sub>(8)</sub>, t = 7.4, p = 7.4·10<sup>−5</sup>) and a power law fit (matched-pairs two-sided t-test<sub>(8)</sub>, t = 5.8, p = 4.1·10<sup>−4</sup>). …”
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1548
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1549
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Validation of primary screen hits reveals compounds that recapitulate increased spheroid size (swell) or decreased MUC5AC in the lumen.
Published 2023“…Compounds that appeared to cause toxicity were identified by observing a significant decrease in spheroid counts in the swell readout or a significant decrease in the total nuclear intensity of the MUC5AC ratio readout. …”
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