Data_Sheet_2_Very Delayed Remote Ischemic Post-conditioning Induces Sustained Neurological Recovery by Mechanisms Involving Enhanced Angioneurogenesis and Peripheral Immunosuppress... by Thorsten R. Doeppner (4020179)

“…Very delayed rPostC on day five, however, induces a pleiotropic effect, among which a stimulation of angioneurogenesis, a modulation of the ischemic extracellular milieu, and a reversal of the stroke-induced immunosuppression occur. …”

Overexpression of truncated trkB induces habits, makes them harder to “break,” and causes depression-like behavior. by Elizabeth T. Barfield (4631341)

“…<i>n</i> = 9–10/group. (g) Finally, vHC <i>Trkb</i>.<i>t1</i> overexpression also decreased responding on a progressive ratio schedule of reinforcement in adulthood, again recapitulating the long-term effects of adolescent CORT exposure. …”

DataSheet_1_Postoperative Long-Term Independence Among the Elderly With Meningiomas: Function Evolution, Determinant Identification, and Prediction Model Development.docx by Haoyi Li (593226)

“…Independent risk factors for postoperative long-term non-independence included: advanced age (70–74 vs. 65–69 OR: 2.631; 95% CI: 1.545–4.481 and ≥75 vs. 65–69 OR: 3.833; 95% CI: 1.667–8.812), recurrent meningioma (OR: 7.791; 95% CI: 3.202–18.954), location in the skull base (OR: 2.683; 95% CI: 1.383–5.205), tumor maximal diameter >6 cm (OR: 3.089; 95% CI: 1.471–6.488), nerves involved (OR: 3.144; 95% CI: 1.585–6.235), high risk of WHO grade and biological behavior (OR: 2.294; 95% CI: 1.193–4.408), recurrence during follow-up (OR: 10.296; 95% CI: 3.253–32.585), lower preoperative KPS (OR: 0.964; 95% CI: 0.938–0.991) and decreased KPS on discharge (OR: 0.967; 95% CI: 0.951–0.984) (P < 0.05). …”

Image_2_Postoperative Long-Term Independence Among the Elderly With Meningiomas: Function Evolution, Determinant Identification, and Prediction Model Development.tif by Haoyi Li (593226)

“…Independent risk factors for postoperative long-term non-independence included: advanced age (70–74 vs. 65–69 OR: 2.631; 95% CI: 1.545–4.481 and ≥75 vs. 65–69 OR: 3.833; 95% CI: 1.667–8.812), recurrent meningioma (OR: 7.791; 95% CI: 3.202–18.954), location in the skull base (OR: 2.683; 95% CI: 1.383–5.205), tumor maximal diameter >6 cm (OR: 3.089; 95% CI: 1.471–6.488), nerves involved (OR: 3.144; 95% CI: 1.585–6.235), high risk of WHO grade and biological behavior (OR: 2.294; 95% CI: 1.193–4.408), recurrence during follow-up (OR: 10.296; 95% CI: 3.253–32.585), lower preoperative KPS (OR: 0.964; 95% CI: 0.938–0.991) and decreased KPS on discharge (OR: 0.967; 95% CI: 0.951–0.984) (P < 0.05). …”

Image_1_Postoperative Long-Term Independence Among the Elderly With Meningiomas: Function Evolution, Determinant Identification, and Prediction Model Development.tif by Haoyi Li (593226)

“…Independent risk factors for postoperative long-term non-independence included: advanced age (70–74 vs. 65–69 OR: 2.631; 95% CI: 1.545–4.481 and ≥75 vs. 65–69 OR: 3.833; 95% CI: 1.667–8.812), recurrent meningioma (OR: 7.791; 95% CI: 3.202–18.954), location in the skull base (OR: 2.683; 95% CI: 1.383–5.205), tumor maximal diameter >6 cm (OR: 3.089; 95% CI: 1.471–6.488), nerves involved (OR: 3.144; 95% CI: 1.585–6.235), high risk of WHO grade and biological behavior (OR: 2.294; 95% CI: 1.193–4.408), recurrence during follow-up (OR: 10.296; 95% CI: 3.253–32.585), lower preoperative KPS (OR: 0.964; 95% CI: 0.938–0.991) and decreased KPS on discharge (OR: 0.967; 95% CI: 0.951–0.984) (P < 0.05). …”

Image_3_Postoperative Long-Term Independence Among the Elderly With Meningiomas: Function Evolution, Determinant Identification, and Prediction Model Development.tif by Haoyi Li (593226)

“…Independent risk factors for postoperative long-term non-independence included: advanced age (70–74 vs. 65–69 OR: 2.631; 95% CI: 1.545–4.481 and ≥75 vs. 65–69 OR: 3.833; 95% CI: 1.667–8.812), recurrent meningioma (OR: 7.791; 95% CI: 3.202–18.954), location in the skull base (OR: 2.683; 95% CI: 1.383–5.205), tumor maximal diameter >6 cm (OR: 3.089; 95% CI: 1.471–6.488), nerves involved (OR: 3.144; 95% CI: 1.585–6.235), high risk of WHO grade and biological behavior (OR: 2.294; 95% CI: 1.193–4.408), recurrence during follow-up (OR: 10.296; 95% CI: 3.253–32.585), lower preoperative KPS (OR: 0.964; 95% CI: 0.938–0.991) and decreased KPS on discharge (OR: 0.967; 95% CI: 0.951–0.984) (P < 0.05). …”

Data_Sheet_1_Anti-hyperuricemic and Anti-inflammatory Effects of Marantodes pumilum as Potential Treatment for Gout.docx by Eldiza Puji Rahmi (8584506)

“…The anti-hyperuricemic activity was initially assessed by XO inhibition with a spectrophotometric in vitro assay. The most active extract was further investigated on hyperuricemic rat model induced by potassium oxonate to determine serum uric acid levels and liver XO effect. …”

DataSheet_3_mTORC1 Inhibition Protects Human Regulatory T Cells From Granzyme-B-Induced Apoptosis.docx by Siawosh K. Eskandari (12858206)

“…<p>Regulatory T cells (T_regs) have shown great promise as a means of cellular therapy in a multitude of allo- and auto-immune diseases—due in part to their immunosuppressive potency. …”

DataSheet_1_mTORC1 Inhibition Protects Human Regulatory T Cells From Granzyme-B-Induced Apoptosis.xlsx by Siawosh K. Eskandari (12858206)

“…<p>Regulatory T cells (T_regs) have shown great promise as a means of cellular therapy in a multitude of allo- and auto-immune diseases—due in part to their immunosuppressive potency. …”

DataSheet1_Numerical evaluation of methanol synthesis in catalytic wall-coated microreactors: scale-up and performance analysis of planar and monolithic designs.docx by João Lameu da Silva (19305355)

“…In particular, the MRP showed a potential feature for scale-up due to the decreased pressure drop. …”

Table1_Changes in postoperative opioid prescribing across three diverse healthcare systems, 2010–2020.pdf by Jean Coquet (12867691)

“…Over the study period, MME decreased significantly at VHA (37.5–30.1; p = 0.002) and Medicaid (41.6–31.3; p = 0.019), and increased at AMC (36.9–41.7; p < 0.001). …”

Temporal Gene Expression Profiling during Rat Femoral Marrow Ablation-Induced Intramembranous Bone Regeneration by Joel K. Wise (240576)

“…<div><p>Enhanced understanding of differential gene expression and biological pathways associated with distinct phases of intramembranous bone regeneration following femoral marrow ablation surgery will improve future advancements regarding osseointegration of joint replacement implants, biomaterials design, and bone tissue engineering. A rat femoral marrow ablation model was performed and genome-wide microarray data were obtained from samples at 1, 3, 5, 7, 10, 14, 28, and 56 days post-ablation, with intact bones serving as controls at Day 0. …”

Supercoil DNA relaxation assay and ROS quantification assays by flow-cytometry. by Ana K. Ibarrola-Vannucci (10573898)

“…Lanes 5–7: DNA plus 50 μM FeCl₃, 10 mM H₂O_2, and decreasing PHB2 concentrations of 500, 250 and 125 μg/mL, respectively. …”

Molecular regulation of miR-378 on the development of mouse follicle and the maturation of oocyte in vivo by Xiao-Feng Sun (149119)

“…The results showed that CMV-miR-378 lentivirus transduction in the mouse ovaries resulted in reduced ovary size, extended oestrous cycle (6-7 d in miR-378 overexpression group and 4–5 dyas in GFP control group) due to continuous oestrum, decreased percentage of oocytes in vitro maturation rate (IVM 60.8% vs. 89.4% in GFP control), increased apoptosis rate (Bax/Bcl2 in mRNA and protein level), decreased expression of genes associated with gap junction, such as connexin 43 (Cx-43) and connexin (Cx-37) and decreased expression of genes associated with follicular development, such as BMP15 and GDF9. …”

Constitutive heterochromatin controls nuclear mechanics, morphology, and integrity through H3K9me3 mediated chromocenter compaction, Manning et al raw data by Gianna Manning (19858309)

“…Nuclear stiffness increases upon loss of H3K9me2 and decreases upon loss of H3K9me3.</b></p><p dir="ltr"><b>Figure 5. …”

Palmitate-induced loss of caveolin-3 from the T-tubule system in the heart. by Catherine J. Knowles (400844)

“…<p><b>A</b>) Localization of caveolin-1 and -3 in confocal images of isolated cardiomyocytes from mice fed standard, MCT or palmitate diet for 12 weeks. …”

Alternative splicing events affecting PTPRC exons 4 to 7. by Charlotte Vandermeulen (11457794)

“…(B) Increased inclusion of exon 4. Decreased inclusion of exon 5 (C), 6 (D) and 7 (E). …”

Image_1_Effect of supplemental parenteral nutrition on all-cause mortality in critically Ill adults: A meta-analysis and subgroup analysis.TIF by Peng Li (69518)

“…SPN plus EN support was associated with a significantly decreased risk of infection (OR = 0.83, 95% CI: 0.74–0.93, P = 0.001), although the duration of mechanical ventilation [standardized mean difference (SMD) = − 0.20], length of hospital stay (SMD = 0.12), and ICU stay (SMD = − 0.57) were similar between the two groups (all P > 0.05). …”

Image_4_Effect of supplemental parenteral nutrition on all-cause mortality in critically Ill adults: A meta-analysis and subgroup analysis.PNG by Peng Li (69518)

“…SPN plus EN support was associated with a significantly decreased risk of infection (OR = 0.83, 95% CI: 0.74–0.93, P = 0.001), although the duration of mechanical ventilation [standardized mean difference (SMD) = − 0.20], length of hospital stay (SMD = 0.12), and ICU stay (SMD = − 0.57) were similar between the two groups (all P > 0.05). …”

Image_1_Effect of supplemental parenteral nutrition on all-cause mortality in critically Ill adults: A meta-analysis and subgroup analysis.TIF by Peng Li (69518)

“…SPN plus EN support was associated with a significantly decreased risk of infection (OR = 0.83, 95% CI: 0.74–0.93, P = 0.001), although the duration of mechanical ventilation [standardized mean difference (SMD) = − 0.20], length of hospital stay (SMD = 0.12), and ICU stay (SMD = − 0.57) were similar between the two groups (all P > 0.05). …”