A single low dose of Tb085-SG3376 was able to cure infection in a mouse model of trypanosomiasis. by Paula MacGregor (198985)

“…BLI was performed prior to any treatment at 3 dpi and then at regular time points following treatment on 3 dpi with a single intravenous dose of (1) 0.25 mg/kg Tb085-SG3376 (n = 5), (2) 0.25 mg/kg NIP228-SG3376 (n = 5) or (3) PBS alone (n = 5). …”

DataSheet_1_Effectiveness and Durability of mRNA Vaccine-Induced SARS-CoV-2-Specific Humoral and Cellular Immunity in Severe Asthma Patients on Biological Therapy.pdf by Michal Podrazil (12571591)

“…<p>Coronavirus disease 2019 (COVID-19) vaccines effectively elicit humoral and cellular immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in healthy populations. This immunity decreases several months after vaccination. …”

Image_1_Gut Microbiome and Bile Acid Metabolism Induced the Activation of CXCR5+ CD4+ T Follicular Helper Cells to Participate in Neuromyelitis Optica Spectrum Disorder Recurrence.... by Xi Cheng (296756)

“…Herein, we reported several key observations. First, there was a lower frequency of circulating Tfh cells in patients with an ARR of<1 than in those with an ARR of ≥1 (P< 0.05). …”

IL-1β or TNF-α induces gene expression of <i>EBI3</i> in MSCs in a dose-dependent manner. by Tong Zhang (103827)

(A) A schematic diagram illustrating human KIF4 domains and the key regions is presented at the top of the Figure. by Sameh A. Gad (12269979)

<i>Leishmania mexicana</i> upregulates c-MET expression on neutrophil surface. by Katiuska Passelli (11965496)

Sweat response in WT, corin KO, and corin hcKO mice. by Meiling He (10151423)

Differential suppression of a gelsolin sequence-tagged reporter gene by miR-133a isomiRs. by Mary K. McGahon (422181)

“…<p>HEK293 cells were transfected with expression plasmids encoding mCherry with a 3′ partial gelsolin sequence and pSM30 containing inserts for miR-133a, miR-133a(v), a random non-targeting sequence (NTC) or siRNA against mCherry (siR-mCh). …”

Image_5_Global, regional, and national years lived with disability due to blindness and vision loss from 1990 to 2019: Findings from the Global Burden of Disease Study 2019.TIF by Shasha Li (139491)

DataSheet1_Anopheles stephensi Feeding, Flight Behavior, and Infection With Malaria Parasites are Altered by Ingestion of Serotonin.docx by Anna M. Briggs (12006497)

“…In addition to these effects, treatment of A. stephensi with 5-HT associated with severe malaria increased infection success with P. y. yoelii 17XNL compared to control, while treatment with healthy levels of 5-HT decreased infection success with P. falciparum. …”

Upregulation of Cx30 impairs pyramidal cell excitability and action potential properties. by Eléonore Hardy (15208385)

Relationship between task-evoked activation and differences between task-based and resting state FC. by Paulina Kieliba (6577226)

Figure 6 A Effect of CMC 2.24 on TNF-a inflammatory cytokine production.xlsx by Osama Abdel-Razek (8981510)

R2/R4 neurons show increased Ca²⁺ influx upon death exposure and were sufficient to alter fly lifespan when activated in the absence of dead. by Christi M. Gendron (14200157)

Downregulation of microRNA-145 may contribute to liver fibrosis in biliary atresia by targeting ADD3 by Yongqin Ye (4432831)

“…</p><p>Results</p><p>MiR-145 was shown to be down-regulated in liver tissues of infants with BA compared to CC (<i>p</i> = 0.0267). ADD3, verified as a target of miR-145-5p, was shown to be overexpressed in infants with BA at the mRNA level (<i>p</i> = 0.0118). …”

GQ-16 reduces brown adipose tissue mass and adipocyte diameter. by Michella S. Coelho (2637202)

Intervention Scenarios with Limited AV Supplies: Global Attack Rates by Vittoria Colizza (84817)

“…Given the rate of distribution <i>p_AV</i>, the value of the reproductive rate <i>R₀</i> up to which cooperative strategies effectively contain the pandemic are reported, <i>R₀ =</i> 1.9 and <i>p_AV</i> = 0.7/d (A), <i>R₀</i> = 1.7 and <i>p_AV</i> = 0.5/d (C), <i>R₀</i> = 1.5 and <i>p_AV</i> = 0.3/d (E).…”

A weakening nitrogen sensitivity of plant productivity over four decades (1976-2016) in a Tibetan alpine grassland by Jinzhou Wang (8206284)

“…N response efficiency was significantly affected by mean annual temperature and monthly precipitation at the key growing stage (i.e., leaf-out phase in April and fast-growing phase in June), and decreased over the past four decades by a rate of -0.68 g g^-1 N yr^-1. …”

Lmod2 influences pyrene emission in actin filaments. by Dávid Szatmári (4510156)

DataSheet_1_Long term follow-up of humoral and cellular response to mRNA-based vaccines for SARS-CoV-2 in patients with active multiple myeloma.docx by Katia Mancuso (14998188)

“…D3 (94 patients) increased the seroconversion rate to 99% in MM patients and the median IgG titer in both groups (up to 2500 U/mL), maintained at T12. 47% of MM patients displayed a positive CMI at T12 and double-negativity for humoral and CMI (9.6% at T3) decreased to 1%. …”