DataSheet_1_Systemic effects of hypophosphatasia characterization of two novel variants in the ALPL gene.docx by Luis Martínez-Heredia (17722704)

“…Introduction<p>Hypophosphatasia (HPP) is an inborn metabolic error caused by mutations in the ALPL gene encoding tissue non-specific alkaline phosphatase (TNSALP) and leading to decreased alkaline phosphatase (ALP) activity. Although the main characteristic of this disease is bone involvement, it presents a great genetic and clinical variability, which makes it a systemic disease.…”

Table_1_Salt Stress Modulates the Landscape of Transcriptome and Alternative Splicing in Date Palm (Phoenix dactylifera L.).XLSX by Zhongliang Xu (2289415)

“…<p>Date palm regards as a valuable genomic resource for exploring the tolerance genes due to its ability to survive under the sever condition. …”

Image2_Nanoscaled biphasic calcium phosphate modulates osteogenesis and attenuates LPS-induced inflammation.JPEG by Yi-Chun Su (17473050)

“…Our results reveal that treating human osteoblasts with 0.5 μg/mL biphasic calcium phosphate nanomaterials results in a marked increase in alkaline phosphatase (ALP) activity and the upregulation of osteogenesis-related genes. …”

DataSheet6_Nanoscaled biphasic calcium phosphate modulates osteogenesis and attenuates LPS-induced inflammation.ZIP by Yi-Chun Su (17473050)

“…Our results reveal that treating human osteoblasts with 0.5 μg/mL biphasic calcium phosphate nanomaterials results in a marked increase in alkaline phosphatase (ALP) activity and the upregulation of osteogenesis-related genes. …”

Image6_Integrative analysis of the role of BOLA2B in human pan-cancer.TIF by Mingxing Liang (11361621)

“…Post-transcriptional modifications, including m5C, m1A, and m6A, were observed to regulate BOLA2B expression in all cancers. …”

DataSheet_1_Plasma protein profiling reveals dynamic immunomodulatory changes in multiple sclerosis patients during pregnancy.docx by Georgia Papapavlou Lingehed (13174338)

“…Pregnancy represents a natural modulation of the disease course, where the relapse rate decreases, especially in the 3^rd trimester, followed by a transient exacerbation after delivery. …”

Table_6_Salt Stress Modulates the Landscape of Transcriptome and Alternative Splicing in Date Palm (Phoenix dactylifera L.).XLSX by Zhongliang Xu (2289415)

“…<p>Date palm regards as a valuable genomic resource for exploring the tolerance genes due to its ability to survive under the sever condition. …”

Dissecting <em>Phaseolus vulgaris</em> Innate Immune System against <em>Colletotrichum lindemuthianum</em> Infection by Paula Rodrigues Oblessuc (141400)

“…<div><h3>Background</h3><p>The genus <em>Colletotrichum</em> is one of the most economically important plant pathogens, causing anthracnose on a wide range of crops including common beans (<em>Phaseolus vulgaris</em> L.). …”

Table_3_Two Aquaporin Genes, GhPIP2;7 and GhTIP2;1, Positively Regulate the Tolerance of Upland Cotton to Salt and Osmotic Stresses.xls by Anhui Guo (9376225)

“…<p>Aquaporins (AQPs) facilitate the transport of water and small molecules across intrinsic membranes and play a critical role in abiotic stresses. In this study, 111, 54, and 56 candidate AQP genes were identified in Gossypium hirsutum (AD₁), Gossypium arboreum (A₂), and Gossypium raimondii (D₅), respectively, and were further classified into five subfamilies, namely, plasma intrinsic protein (PIP), tonoplast intrinsic protein (TIP), nodulin 26-like intrinsic protein (NIP), small basic intrinsic protein (SIP), and uncategorized X intrinsic protein (XIP). …”

Image1_Nanoscaled biphasic calcium phosphate modulates osteogenesis and attenuates LPS-induced inflammation.JPEG by Yi-Chun Su (17473050)

“…Our results reveal that treating human osteoblasts with 0.5 μg/mL biphasic calcium phosphate nanomaterials results in a marked increase in alkaline phosphatase (ALP) activity and the upregulation of osteogenesis-related genes. …”

DataSheet_1_Soluble CD83 modulates human-monocyte-derived macrophages toward alternative phenotype, function, and metabolism.docx by Katrin Peckert-Maier (13211658)

“…This goes along with a decreased capacity to stimulate alloreactive T cells in mixed lymphocyte reaction (MLR) assays. …”

Diurnal Expression Pattern, Allelic Variation, and Association Analysis Reveal Functional Features of the <i>E1</i> Gene in Control of Photoperiodic Flowering in Soybean by Hong Zhai (524629)

“…The basal expression level of <i>E1</i> was enhanced by the long light phase, and decreased by duration of dark. We identified a 5bp (3 SNP and 2-bp deletion) mutation, referred to an <i>e1-b3a</i>, which occurs in the middle of B3 domain of the <i>E1</i> gene in the early flowering cultivar Yanhuang 3. …”

Table_3_Plasma protein profiling reveals dynamic immunomodulatory changes in multiple sclerosis patients during pregnancy.xlsx by Georgia Papapavlou Lingehed (13174338)

“…Pregnancy represents a natural modulation of the disease course, where the relapse rate decreases, especially in the 3^rd trimester, followed by a transient exacerbation after delivery. …”

Table_4_Aberrant expression of bone morphogenetic proteins in the disease progression and metastasis of breast cancer.docx by Ming Liu (105953)

“…BMPs also play dual roles in tumour growth and metastasis of BC.</p>Conclusion<p>A shift pattern of BMPs was showed in different subtypes of breast cancer suggesting a subtype specific involvement. …”

Image7_Integrative analysis of the role of BOLA2B in human pan-cancer.TIF by Mingxing Liang (11361621)

“…Post-transcriptional modifications, including m5C, m1A, and m6A, were observed to regulate BOLA2B expression in all cancers. …”

Image1_Benchmarking microbial DNA enrichment protocols from human intestinal biopsies.jpg by Dmitrij Marchukov (15356863)

“…However, ONT AS resulted in relevant shifts in the observed bacterial abundance, including 2 to 5 times more Escherichia coli reads. Furthermore, a modest enrichment of Bacteroides fragilis and Bacteroides thetaiotaomicron was also observed with AS. …”

Parallel, High-Quality Proteomic and Targeted Metabolomic Quantification Using Laser Capture Microdissected Tissues by Shichen Shen (1392565)

“…The strategy features: (i) an optimized molecular weight cutoff (MWCO) filter-based separation of proteins and small-molecule fractions with high and consistent recoveries; (ii) microscale derivatization and charge-based enrichment for ultrasensitive quantification of key androgens (LOQ = 5 fg/1k cells) with excellent accuracy/precision; (iii) reproducible/precise proteomics quantification with low-missing-data using a detergent-cocktail-based sample preparation and an IonStar pipeline for reproducible and precise protein quantification with excellent data quality. …”

Table4_Benchmarking microbial DNA enrichment protocols from human intestinal biopsies.XLSX by Dmitrij Marchukov (15356863)

“…However, ONT AS resulted in relevant shifts in the observed bacterial abundance, including 2 to 5 times more Escherichia coli reads. Furthermore, a modest enrichment of Bacteroides fragilis and Bacteroides thetaiotaomicron was also observed with AS. …”

DataSheet_1_The impact of female BMI on sperm DNA damage repair ability of oocytes and early embryonic development potential in intracytoplasmic sperm injection cycles.docx by Yuqing Jiang (13241827)

“…However, in the overweight/obese women group, couples with a sperm DFI≥30% had a significantly lower fertilization rate (76% vs. 72.7%; p=0.027), cleavage rate (98.7% vs. 97.2%; p=0.006), and high-quality embryo rate (67.8% vs. 62.6%; p=0.006) than couples with a sperm DFI<30%.…”

Table_2_Plasma protein profiling reveals dynamic immunomodulatory changes in multiple sclerosis patients during pregnancy.xlsx by Georgia Papapavlou Lingehed (13174338)

“…Pregnancy represents a natural modulation of the disease course, where the relapse rate decreases, especially in the 3^rd trimester, followed by a transient exacerbation after delivery. …”