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641
Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications
Published 2016“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”
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646
Activation of mitoK<sub>ATP</sub> channels decreased the latency time of the transjunctional currents in slice.
Published 2013“…The control experiment is shown in (<b>A1</b>). (<b>B</b>) Bar graph shows that at 6 min after exposure to DIZ, the latency time was decreased by 50% with an average of 234.54±34.43 µs (n = 13). …”
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647
Overexpression of <i>PF10_0355</i> decreases parasite susceptibility to halofantrine (HFN) and related antimalarials.
Published 2011“…Overexpression of <i>PF10_0355</i> decreases parasite susceptibility to (A) HFN and structurally related (B) mefloquine (MFQ) and (C) lumefantrine (LUM). …”
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648
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IL-1Ra treatment decreases activity and increases rest time in <i>mdx</i> mice.
Published 2016“…Graphs represent mean ± SEM and statistically significant differences were determined by parametric, unpaired, two- tailed, t-tests with a p≤0.05 being significant. …”
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Image_3_Evidence for Decreased Density of Calretinin-Immunopositive Neurons in the Caudate Nucleus in Patients With Schizophrenia.TIF
Published 2020“…As expected, small, medium and large CR-ip interneurons were detected in the CN. We found a 38% decrease in the density of all CR-ip interneurons (P < 0.01) that was driven by the loss of the small CR-ip interneurons (P < 0.01) in patients with SCH. …”
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658
Image_2_Evidence for Decreased Density of Calretinin-Immunopositive Neurons in the Caudate Nucleus in Patients With Schizophrenia.TIF
Published 2020“…As expected, small, medium and large CR-ip interneurons were detected in the CN. We found a 38% decrease in the density of all CR-ip interneurons (P < 0.01) that was driven by the loss of the small CR-ip interneurons (P < 0.01) in patients with SCH. …”
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659
Image_5_Evidence for Decreased Density of Calretinin-Immunopositive Neurons in the Caudate Nucleus in Patients With Schizophrenia.TIF
Published 2020“…As expected, small, medium and large CR-ip interneurons were detected in the CN. We found a 38% decrease in the density of all CR-ip interneurons (P < 0.01) that was driven by the loss of the small CR-ip interneurons (P < 0.01) in patients with SCH. …”
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660
Image_1_Evidence for Decreased Density of Calretinin-Immunopositive Neurons in the Caudate Nucleus in Patients With Schizophrenia.TIF
Published 2020“…As expected, small, medium and large CR-ip interneurons were detected in the CN. We found a 38% decrease in the density of all CR-ip interneurons (P < 0.01) that was driven by the loss of the small CR-ip interneurons (P < 0.01) in patients with SCH. …”