Positive modulation of mGluR5 decreases spine density in the nucleus accumbens but not in the dorsal striatum. by Kellie S. Gross (3115299)

“…<p>(A) Twenty-four hours after systemic administration, CDPPB (5–10 mg/kg, <i>n</i> = 18 animals) decreased dendritic spine density and frequency of small head diameter spines (0.2 μm bin) compared to vehicle control (<i>n</i> = 8) in the nucleus accumbens core. …”

Proteasome activity was decreased in the <i>myc-rpt6-S119A</i> mutant. by Esther Magdalena Marquez-Lona (4183126)

“…<p>(A) Lysates from strains in stationary phase (A₆₀₀>5.0) were subjected to native gel electrophoresis followed by an in-gel activity assay with the fluorogenic proteasome substrate Suc-LLVY-AMC. …”

Decreasing ShcA expression enhances TGF-β-induced Smad signaling. by Baby Periyanayaki Muthusamy (838234)

“…<p>(A) Smad3 and Smad2 activation, assessed by pSmad3 or pSmad2 immunoblotting, in NMuMG cells, transfected with control or ShcA siRNA (siShc-a), in the absence of added TGF-β or in response to 2 ng/ml TGF-β for 30 min. …”

Vitamin D3, but not the Cisplatin, could moderately reduce STZ-induced hyperglycemia in mice (a) Schematic representation of experimental protocol followed in the study: After accl... by Vidya G. Bettada (22208808)

“…Interestingly the FBG is increased in the mice treated with cisplatin (2.5 mg/Kg) in the final two time points.</p> <p>(TIF)</p>…”

Targeted point mutation (F639A) in the GluN1 subunit decreases ethanol sensitivity of NMDA receptors. by Carolina R. den Hartog (484817)

Losartan increased ACE-2 expression, while SARS-CoV-2 spike protein decreased ACE-2 expression in hACE2 brains. by Mackenzi Meier (19251139)

“…<p>hACE2 KI mice were treated only with Losartan or intravenously injected with SARS-CoV-2 spike protein (SP, 4 μg/ animal) with or without Losartan (10 mg/kg body weight) for 2 weeks. …”

Data_Sheet_1_The Risky Decrease of Fishing Reference Points Under Climate Change.docx by Morgane Travers-Trolet (548023)

“…The model was first parameterized and run to fit the historical situation (2000–2009) and then used to assess the ecosystem state for the 2050–2059 period, using two contrasting climate change scenarios (RCP 4.5 and RCP 8.5). For each condition, a monospecific MSY estimation routine was performed by varying species fishing mortality independently and allowed estimation of reference points for each species. …”

All data points from Fig 5. by Sara Hijazi (21656615)

“…Following a remyelination period of 5 weeks, PV interneuron properties were only partially recovered, suggesting that transient juvenile demyelination leads to long-lasting impairments of PV interneuron function. …”

TRPM7 regulates intracellular Ca²⁺ and Mg²⁺ concentration of cortical astrocytes. by Zhao Zeng (478844)

“…However, knockdown of TRPM7 in mouse cortical astrocytes significantly decreases intracellular Mg²⁺ by 43.5% ± 9.8% (*, <i>p</i> < 0.05, n = 4). …”

<i>Ep300</i> siRNA suppressed osteoblast differentiation and decreased histone lactylation levels. by Erika Minami (17583343)

The antinociceptive effects produced by the intraperitoneal administration of CoPP at 5 and 10 mg/kg in STZ injected mice. by Sílvia Castany (843274)

Combination treatment induced more cell death and decreased cell survival markers more than did single treatments. by Panchanan Maiti (1459852)

Example of inflection points estimated with a window size of 5. by Taiga Mori (21410076)

<i>In vivo</i> treatment with entinostat decreases Foxp3 expression in Tregs and inhibits Tregs function. by Li Shen (110858)

“…<p>BALB/c mice were treated with vehicle (0.5% methocel) or 5 mg/kg/day or 20 mg/kg/day of entinostat by gavage for 5 days. …”

Absence of adaptive immunity decreases tumor cell damage in MDR1A deficiency. by Eva Maria Hennenberg (4234018)

Down-regulation of Bim in EBV-positive cells is not due to proteosomal degradation or decreased mRNA stability. by Kostas Paschos (262658)

This is the raw data of Immunofluorescence in Met-5A cell. by Yangyang Yin (14323701)

Subjects:

Effects of H5 (20 and 40 mg/kg, p.o.), and diazepam (2.5 mg/kg, i.p.) in the Rota-rod test in mice. by Maria Alice Miranda Bezerra Medeiros (11752002)

Increases in 1,5-anhydrosorbitol and decreases in ascorbic acid following RYGB. by David M. Mutch (37665)

“…B) For ascorbic acid, the ANOVA model did not detect group-specific changes over time (no group:time interaction), but indicated significant decreases from T0 to T6 in both groups. Overall, 1,5-anhydrosorbitol and ascorbic acid were significantly different at each time point between OB and OB/D subgroups (p<0.01, see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0007905#pone-0007905-t002" target="_blank"><b>TABLE 2</b></a>).…”

Diclofenac decreases angiogenesis. by Nina Mayorek (241888)