6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations by Hui Li (32376)

“…After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …”

6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations by Hui Li (32376)

“…After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …”

Design, Synthesis, and Biological Evaluation of [1,2,5]Oxadiazolo[3,4‑<i>b</i>]pyridin-7-ol as Mitochondrial Uncouplers for the Treatment of Obesity and Metabolic Dysfunction-Assoc... by Mary A. Foutz (20361830)

“…Pharmacokinetic studies indicated a half-life of 2 h, <i>C</i>_max of 35 μM, and no observed adverse effects at 1,000 mg kg^–1 dose in mice. …”

Inhibition of MMP2 decreases apoptosis and attenuates insulin secretion dysfunction caused by oxidative stress in INS-1 cells. by Chongxiao Liu (644813)

Mean decrease in accuracy (MDA) of top 15 urine metabolites. by Liam E. Broughton-Neiswanger (8447220)

“…Urine metabolites with a mean decrease in accuracy ≥ 0.004 in at least one post-treatment time point (2–5) were considered for inclusion in the predictive model.…”

Decrease of GFP-TbAtg8 fluorescence during starvation. by Remo S. Schmidt (546946)

Model performance according to number of variables by 5-fold cross-validation. by Gazi Md. Salahuddin Mamun (13905678)

Pneumococci decrease epithelial surface fluid flow and particle transport. by Manfred Fliegauf (391677)

Image_2_Decreased Opioid Consumption in Bone Marrow Harvest Patients Using Quadratus Lumborum Blocks in a Standardized Protocol.PDF by Nicole C. McCoy (12459036)

“…The implementation group showed significantly reduced median intraoperative (20.0 mg vs. 0.0 mg; p < 0.001) and total opioid consumption (20.5 mg vs. 0.0 mg; p < 0.001). …”

Effects of TGF-β1 on the expression of fibrosis indicators in HBdSMCs and the effects of MEL on the expression of fibrosis indicators in HBdSMCs induced by TGF-β1. by Yang Zhang (30734)

Subjects:

Probucol prevents 3-NP-induced decreases in body weight. by Dirleise Colle (422124)

Eligibility criteria for expert judges (≥5 points). by Thiago Serrão-Pinto (17817523)

The effects of GM-CSF on DMN-induced histopathological changes. by Mrigendra Bir Karmacharya (13607415)

<i>A</i>. <i>phagocytophilum</i> infection decreases cytotoxicity in MEG-01 cells. by Supreet Khanal (3560330)

DOX decreases body mass gain over time in a sub-chronic toxicity model. by Gonçalo C. Pereira (156673)

Pre-treatment of striatal slices by DCF decreases HDA uptake (a) and dopamine content (b) by Elisaveta Milusheva (45672)

Basal IKK activity is decreased in cells lacking IRE1. by Arvin B. Tam (124164)

Summary of the A19D unfolding pathway highlighting the main structural changes identified here that might explain its decreased thermodynamic stability. by Priscila Ferreira (498747)

AMS scores decrease over three days at high-altitude. by Erica C. Heinrich (6832055)

mTOR activity is decreased in KSR1-deficient T cells. by Marie Le Borgne (337225)