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441
Renoprotective Effects of Aldose Reductase Inhibitor Epalrestat against High Glucose-Induced Cellular Injury
Published 2017“…Rat renal tubular (NRK-52E) cells were exposed to high glucose (30 mM) or normal glucose (5 mM) media for 24 to 48 hours with or without the AR inhibitor epalrestat (1 muM) and assessed for changes in Akt and ERK1/2 signaling, AR expression (using western blotting), and alterations in mitochondrial membrane potential (using JC-1 staining), cell viability (using MTT assay), and cell cycle. …”
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442
STRUCTURAL AND FUNCTIONAL APPROACHES TOWARD ACTIVITY RESTORATION OF NOVEL CYSTATHIONINE BETA-SYNTHASE MUTATIONS
Published 2024“…This study investigates the impact of five pathogenic CBS missense mutations [c.1006C>T (p.R336C), c.689T>A (p.L230Q), 215A>T (p.K72I), c.707C>A (p.T236N), and c.457G>A (p.G153R)] identified in homocystinuria patients and appeared to be resistant to pyridoxine treatment on the biochemical and biophysical properties of CBS protein. …”
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443
Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics
Published 2018“…In contrast, in the presence of Ca2+, there was a significant decrease in the stability of the five proteins following the order CaMWT> CaMN98I > CaMD132E > CaMQ136P > CaMD134H. …”
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444
Three dimensional evaluation of the skeletal and temporomandibular joint changes following stabilization splint therapy in patients with temporomandibular joint disorders and mandi...
Published 2023“…The value of the difference from the bilateral condyle head position to the X and Z axes significantly decreased from 2.50 ± 1.56 mm and 2.30 ± 1.57 mm to 1.64 ± 1.58 mm and 1.82 ± 1.11 mm, respectively. …”
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445
The Effects of Class IV Hemorrhagic Hypotensive Shock and Its Resuscitation with Fluids and Adjuvant Vasopressors or Cellular Energy Replenishment on the Splanchnic Microcirculatio...
Published 2016“…In all four groups, class IV hemorrhagic shock remarkably decreased hemoglobin, hematocrit and produced a metabolic acidosis characterized by low pH, PCO2, HCO3, TCO2 and an increase in the base deficit as compared with the baseline pre-hemorrhage levels. …”
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446
Environmental Factors Affecting the Growth and Enzymatic Activity of Ceratocystis Radicicolathe Causal Agent of Black Scorch Disease on Date Palm
Published 2016“…To optimize the fungus growth, pH media was adjusted at different levels (5.5, 6, 6.5, 7, 7.5 and 8). In addition, standard Czapek broth media was used as a control. …”
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447
Flight Scheduling in the Airspace
Published 2016“…In this study, we developed a scatter search (SS) to deal with larger instances. …”
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448
Mixed Solid Municipal Waste-Based Biochar for Soil Fertility and Greenhouse Gas Mitigation
Published 2016“…Municipal solid waste management is one of the major challenges facing Qatar with more than 2.5 million tons of municipal solid waste each year, a very high waste generation rate in a country with small land mass. …”
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449
Effects of Climate and Atmospheric Nitrogen Deposition on Early to Mid-Term Stage Litter Decomposition Across Biomes
Published 2021“…We assessed how macroclimate and atmospheric inorganic N deposition under current and predicted scenarios (RCP 2.6, RCP 8.5) might affect litter mass loss measured after 3 and 12 months. …”
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450
Infliximab versus ciclosporin in steroid resistant acute severe ulcerative colitis: a model-based cost-utility analysis of data from CONSTRUCT pragmatic trial.
Published 2023“…The decision tree mirrored trial-based results. Beyond 2-year trial follow-up, Markov model predicted a decrease in colectomy rate, but it remained slightly higher for ciclosporin. …”
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451
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452
Silicon Enhances Morpho–Physio–Biochemical Responses in Arsenic Stressed Spinach (Spinacia oleracea L.) by Minimizing Its Uptake
Published 2022“…Fifteen days old seedlings of S. oleracea were subjected to the different concentrations of As, i.e., 0 (no As), 50, and 100 µM in the soil which were also supplied with the different exogenous levels of Si, i.e., 0 (no Si), 1.5, and 3 mM. Results from the present study revealed that the As toxicity induced a substantial decreased in shoot length, root length, number of leaves, leaf area, shoot fresh weight, root fresh weight, shoot dry weight, root dry weight, chlorophyll-a, chlorophyll-b, total chlorophyll, carotenoid content, net photosynthesis, stomatal conductance, transpiration rate, soluble sugar, reducing sugar, non-reducing sugar contents, calcium (Ca2+), magnesium (Mg2+), iron (Fe2+), and phosphorus (P) contents in the roots and shoots of the plants. …”
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453
Privacy-preserving federated learning cyber-threat detection for intelligent transport systems with blockchain-based security
Published 2022“…Subsequently, by using blockchain and by applying an aggregation strategy to different models, models from the previous step were uploaded in a smart contract. Lastly, we returned the updated models to the vehicles. …”
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454
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455
Infliximab versus ciclosporin in steroid resistant acute severe ulcerative colitis: a model-based cost-utility analysis of data from CONSTRUCT pragmatic trial
Published 2023“…Results The decision tree mirrored trial-based results. Beyond 2-year trial follow-up, Markov model predicted a decrease in colectomy rate, but it remained slightly higher for ciclosporin. …”
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456
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457
Utilizing Recycled Polypropylene Fibers as Reinforcement for Concrete Beams
Published 2020“…The various fiber content ratios tested in this investigation are 0.25, 0.5 and 1%. Based on the results of this study, the presence of recycled PP fibers in concrete decreases its workability; the addition of an adequate superplasticizer to the concrete mix becomes then necessary. …”
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458
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459
Effect of Seagrass Liquid Extracts on Bell Pepper (Capsicum annuum) Under Salt stress Conditions.
Published 2020“…The results showed an increase in relative water content (RWC) of salt stressed bell pepper plants sprayed with seagrass extract from 0- 100 mM of NaCl treatment, while RWC decreased at 150 and 200 mM NaCl treatments compared to the control. …”
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460
Experimental Investigation of Foam drilling fluid using Visualization Technique
Published 2021“…The experiments were conducted in a 6.16 m long horizontal pipe with 2.5 in. inner diameter and 4.5 in. outer diameter and annular diameter ratio of 1.8. …”
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