Aquaporin 2 Mutations in <i>Trypanosoma brucei gambiense</i> Field Isolates Correlate with Decreased Susceptibility to Pentamidine and Melarsoprol by Fabrice E. Graf (469055)

“…Here we describe two different kinds of <i>TbAQP2</i> mutations found in <i>T. b. gambiense</i> field isolates: simple loss of <i>TbAQP2</i>, or loss of wild-type <i>TbAQP2</i> allele combined with the formation of a novel type of <i>TbAQP2/3</i> chimera. The identified mutant <i>T. b. gambiense</i> are 40- to 50-fold less sensitive to pentamidine and 3- to 5-times less sensitive to melarsoprol than the reference isolates. …”

Cardamonin decreased the protein level of Raptor and suppressed lipogenesis and CPT-1. by Peiguang Niu (17044532)

Telmisartan decreased NO production in LPS-stimulated BV2 and primary neonatal rat glial cells. by Nofar Torika (3169497)

Quantitative antibody and antigen responses to nMAb vs placebo day 1-90: Pooled analysis of neutralizing monoclonal antibodies. by Elizabeth S. Munroe (21568166)

Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis-6 by Mrigank Srivastava (94935)

“…(F, G) staining with isotype-matched control antibody; (H, I) cathepsin K specific staining. Arrows point to alveolar macrophages . Photogmicrographic illustration is representative of at least n = 3 independent analyses. …”

Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis-0 by Mrigank Srivastava (94935)

“…(F, G) staining with isotype-matched control antibody; (H, I) cathepsin K specific staining. Arrows point to alveolar macrophages . Photogmicrographic illustration is representative of at least n = 3 independent analyses. …”

Constitutive KIT activation in cells with gain-of function KIT mutations causes increased ROS levels and decreased DJ-1. by Do-Kyun Kim (2176492)

RNAP II CTD phosphoserine-2 levels decreased with increasing amounts of DRB. by Mark Ou (474248)

Antibody response elicited by SARS-CoV-2 vaccines. by Chris Davis (647632)

IRE1 depletion decreases heterochromatin, DNA and H3K9me3 methylation, and UHRF1. by Iratxe Zuazo-Gaztelu (21071939)

Mfsd2a KO mice have decreased liver TG with normal liver metabolism. by Justin H. Berger (297156)

Decreased F4/80⁺ macrophages in the presence of PLD inhibitors using IF microscopy of lung sections. by Karen M. Henkels (3350273)

Subjects:

Decreased Ly6G⁺ neutrophils in the presence of PLD inhibitors using IF microscopy of lung sections. by Karen M. Henkels (3350273)

Subjects:

Retnla overexpression decreased the levels of IL-4, IL-5, and IL-13 in OVA-induced asthmatic lung. by Mi-Ran Lee (664596)

TviA is involved in a rapid decrease in flagella expression in serum. by Sebastian E. Winter (133801)

Mutations eliminating positive charge from the C-terminal helix of UNO decrease chromatin binding of SU and interfere with normal chromosome conjunction during meiosis. by Zeynep Kabakci (9449519)

M1-37T protein is degraded in a lysosome-independent manner, and its ubiquitination is not through K48 linkage. by Chenxi Wang (284364)

Subjects:

MYCN overexpression leads to decreased <i>id2a</i> expression in early SCG. by Rodrigo Ibarra-García-Padilla (19697623)

Models of G48D, M78I, G125C, and A146V RAD52 point mutants. by Abdulaziz B. Hamid (13804692)

Unusual [3+1] Cycloaddition of a Stable Silylene with a 2,3-Diazabuta-1,3-diene versus [4+1] Cycloaddition toward a Buta-1,3-diene by Yun Xiong (1403545)

“…Cycloaddition reactions of the thermally stable N-heterocyclic silylene LSi: <b>1</b> {L = CH[(CCH₂)CMe][N(Ar)]₂], Ar = 2,6-<i>i</i>Pr₂C₆H₃} with acetone azine (1,1,4,4-tetramethyl-2,3-diazabuta-1,3-diene) and buta-1,3-diene derivatives have been probed. …”