Loss of Cntnap2 decreases specifically stabilization of new spines. by Amos Gdalyahu (3213810)

“…<p><b>a.</b> From left to right: Chronic imaging through a cranial window of L5 pyramidal neuron. …”

LGP2 deficiency decreases intracellular dsDNA signaling. by Darja Pollpeter (353259)

S1 Table - Non-Cellulosic Polysaccharides from Cotton Fibre Are Differently Impacted by Textile Processing by Jean-Luc Runavot (657205)

G0S2 stability is decreased in mice lacking ATGL. by Bradlee L. Heckmann (2818306)

Tissue, days post-infection (dpi) and the top 10 most significant genes with increased and decreased expression with valid gene symbols for the response contrasts. by Gillian P. McHugo (8965919)

A37 increases the M1 protein stability and viral pathogenicity of H5N6 virus. by Chenxi Wang (284364)

Subjects:

IFN-β signalling pathway stimulation by Poly(I:C) decreased 5’terminally deleted CVB3 RNA forms viral loads, cardiac lesions and mortality in DBA/2J mice. by Domitille Callon (17723936)

PKCε activation induces aggrecan gene expression, decreases ADAMTS5, and detection of ADAMTS-5-depended cleavage of ECM aggrecan through upregulation of hsa-miR-377 expression. by Emmanouella Tsirimonaki (490707)

“…<p>(<b>A</b>) RT-PCR detected the relative expression of ACAN, MKI67, ADAMTS5 after treatment of NP cells with 1 μM ψεRACK (or vehicle) for indicated times and revealed that time-dependent activation of PKCε significantly increased the mRNA expression for aggrecan, while in an opposing manner decreased ADAMTS5; mRNA levels of the proliferation marker Ki67 became barely detectable after 8 hours of PKCε activation. …”

Depletion of PfPKAc in NF54/AP2-G-mScarlet/PKAc cKD parasites leads to a block in merozoite invasion and decreases gametocyte rigidity. by Eva Hitz (10877688)

Vectorized siRNA TMPRSS2-ERG IV-SQ impaired tumour growth and restored differentiation <i>in vivo</i>. by Giorgia Urbinati (554921)

“…<p><b>a.</b> SCID mice (n = 5/group) bearing VCaP tumour xenografts were injected intravenously either with NaCl 0.9%, non-vectorized siRNA TMPRSS2-ERG IV, NPs siRNA control-SQ or NPs siRNA TMPRSS2-ERG IV-SQ twice per week during 6 weeks (1.8 mg/kg/mouse cumulative dose). …”

Evaluation of T-cell activation by using ELISpot assays in vaccinated mice (N = 5–7). by Ryo Kawakami (4849549)

SUR1Δ/LDLR^-/- mice have increased fasting glucose levels and impaired glucose tolerance with decreased insulin secretion. by Erika Gurzeler (4781904)

Dynamics of CHT internalization are altered by acute insulin treatment. by Katherine J. Fishwick (768451)

MSCs decrease oligodendrocyte death. by Justin D. Glenn (800439)

Dynamics of CHT trafficking are altered by LY294002 treatment. by Katherine J. Fishwick (768451)

Bacterial load in lung and spleen of binge-drinking mice intranasally infected with decreasing doses of <i>B</i>. <i>thailandensis</i>. by Victor M. Jimenez Jr. (8107853)

Decreased 11ß-HSD1 protein level by IGF-I overexpression <i>in vivo</i> and a direct treatment with IGF-I. by Subrata Chowdhury (787208)

“…The result of Western blotting was corrected with that of β-actin. N = 4, **P<0.01 vs. untreated. <b>D</b>. IGF-I treatment accelerated 11β-HSD1 protein degradation in 11β-HSD1 overexpressing MIN6 cells (as in Figs <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0136656#pone.0136656.g005" target="_blank">5</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0136656#pone.0136656.g006" target="_blank">6</a>). …”

D257A mice display decreased mRNA expression of nuclear genes encoding components of ETC Complexes I, III and IV. by Asimina Hiona (246175)

Proline catabolism is induced by proline in a Put3-dependent and -independent manner. by Fitz Gerald S. Silao (9384713)

Parvalbumin-positive interneurons (PV-INs) in perilesional tissue respond to optogenetic stimulation and are involved in voluntary movement, but show a decreased firing rate. by Livia Vignozzi (22430567)

“…<b>B</b>, Motor function assessment in the Gridwalk test before and 2 days after stroke induction in sham (<i>n </i>=<i> </i>5, gray bar plots) and stroke (<i>n </i>=<i> </i>5, purple bar plots) animals, circles represent single animals (two-way ANOVA followed by Tukey test *** <i><i>P</i></i> < 0.001). …”