Image2_Anti-hyperglycemic effects of Cissus quadrangularis extract via regulation of gluconeogenesis in type 2 diabetic db/db mice.TIF by Jeong-Won Kim (18464976)

“…In this study, the therapeutic effects of C. quadrangularis extract (CQR-300) on type 2 diabetes mellitus (T2DM) were investigated in a leptin receptor-mutated db/db mouse model.…”

TCP24 interacts with the TGMV <i>CP</i> promoter <i>in vivo</i>. by Jacqueline Williams (3493745)

The DIP2A-cortactin interaction is critical for mediating ac-cortactin. by Jun Ma (9393)

“…(E and F) Ac-cortactin levels were decreased in a concentration-dependent pattern (ac-cortactin, Pearson correlation = −0.656, *<i>P =</i> 0.0205; ac-tub, Pearson correlation = 0.279, n.s. …”

Hepcidin quantification by WCX-TOF MS in human samples that were pre-incubated with 0, 5 or 10 nM of PRS-080 to block binding of hepcidin to the WCX beads. by Coby M. M. Laarakkers (228091)

DataSheet1_Zebrafish EEG predicts the efficacy of antiepileptic drugs.pdf by Jun-Nyeong Shin (14234054)

“…The antiepileptic effect was determined by observing a significant decrease in at least one out of three indicators of the number, total duration, and mean duration of ictal events.…”

MeCP2 expression in excitatory versus inhibitory cells of the developing dLGN. by Yuki Yagasaki (402238)

“…P30: 774 cells for 6 animals. P50: 463 cells for 5 animals. <b>(D)</b> The number of GABAergic and glutamatergic neuron in 10000 μm² decreased between P10 and P20. …”

Effects of naphthazarin, oxoline and menadione on <i>skn-1</i> and Nrf2 targets in <i>C. elegans</i> and HepG2 cells. by Piper R. Hunt (214052)

“…Data are mean beta-lactamase activity ± SEM (n = 3−4). (D) HepG2 cells were treated with plumbagin (diamonds), naphthazarin (shaded diamonds) or oxoline (triangles) at indicated concentrations. …”

High-Pressure- and Low-Temperature-Induced Changes in [(CH₃)₂NH(CH₂)₂NH₃][SbCl₅] by Maciej Bujak (1645039)

“…The intermolecular distances continuously decrease with further increase in pressure, and at ∼3.1 GPa, zigzag [{SbCl₅}<i>_n</i>]²<i>ⁿ</i>^- chains containing corner-sharing [SbCl₆]^3- octahedra are formed. …”

Selected mutations in the folate transporter FT1 and their analysis by DNA editing. by Sophia Bigot (16469992)

Changes in body length after exposure to organic solvents. by Masahiro Tomioka (430683)

Altered membrane properties and reduced stability of RBC_VL after sensitization with anti-9-<i>O</i>-AcSGP IgG_VL antibodies. by Sajal Samanta (148083)

“…FCS was measured of RBC_N (upper left panel) and of RBC_VL without sensitization (upper right panel) or with sensitization with anti-9-<i>O</i>-AcSGP IgG_VL (2.5 µg/ml) (lower left panel) or treatment with A23187 (1.0 µM) (lower right panel). …”

Tetradentate Platinum(II) and Palladium(II) Complexes Containing Fused 6/6/6 or 6/6/5 Metallocycles with Azacarbazolylcarbazole-Based Ligands by Yuanbin She (2162245)

“…The time-dependent density functional theory (TD-DFT) calculations and natural transition orbital (NTO) analyses reveal that the Pt­(II) complexes possess 10.8–15.2% metal-to-ligand charge transfer (³MLCT) mixed with ligand-centered (³LC) characters, by contrast, the Pd­(II) complexes exhibit significantly decreased 4.2–7.1% ³MLCT characters and enhanced ³LC compositions. …”

Activity of miR-124 and miR-23a in NSC-derived neurons and astrocytes. by Annalisa Lattanzi (427545)

“…(B–E) A significant decrease of GFP expression is observed in bdLV.miRT124-transduced neurons (βtubIII, MAP2) (<b>B, C</b>) and in bdLV.miRT23a-transduced astrocytes (GFAP) and immature glial cells (nestin) (<b>D, E</b>). …”

Bioassay and NMR-HSQC-Guided Isolation and Identification of Phthalide Dimers with Anti-Inflammatory Activity from the Rhizomes of Angelica sinensis by Hongyan Wen (9226895)

“…Among them, compound <b>9</b> showed a remarkable inhibitory activity with IC₅₀ values of 425 nM and could significantly decrease IL-1β and IL-6 transcription levels. …”

Bioassay and NMR-HSQC-Guided Isolation and Identification of Phthalide Dimers with Anti-Inflammatory Activity from the Rhizomes of Angelica sinensis by Hongyan Wen (9226895)

“…Among them, compound <b>9</b> showed a remarkable inhibitory activity with IC₅₀ values of 425 nM and could significantly decrease IL-1β and IL-6 transcription levels. …”

Effective quantum yield of photosystem II (Yield II) of <i>Klebsormidium crenulatum</i> during desiccation (desiccated over 100 g of silica gel) monitored by PAM 2500. by Andreas Holzinger (153856)

“…The results of three filters containing similar amount of algal biomass are shown individually, to demonstrate that the decrease of Y II occurred within a short time frame (40–50 min). …”

Platinum-Based Modification of Styrylbenzylsulfones as Multifunctional Antitumor Agents: Targeting the RAS/RAF Pathway, Enhancing Antitumor Activity, and Overcoming Multidrug Resis... by Zhikun Liu (389939)

“…Among them, compound <b>29</b> showed the most potent antitumor activity in vitro with IC₅₀ values at the nanomolar level against the tested tumor cell lines and 1000-fold higher than cisplatin against the multidrug resistant cells (A549/CDDP, A549/DOX, and SKOV-3/CDDP cells), while it showed only moderate cytotoxicity against normal cells (HEUVC cells). …”

Validation of selected genes associated with p53 connection pathway was carried out using quantitative real-time polymerase chain reaction (qRT-PCR) and western immunoblotting. by Mei Yi Sim (4067998)

Comparison of participation in decision-making. by Yoriko Aoki (17847445)

“…</p><p>Results</p><p>Ninety-nine participants (intervention group n = 51; control group n = 48) were included in the full analysis set, with a dropout rate of 38.4%. …”

Characteristics of participants at baseline. by Yoriko Aoki (17847445)

“…</p><p>Results</p><p>Ninety-nine participants (intervention group n = 51; control group n = 48) were included in the full analysis set, with a dropout rate of 38.4%. …”