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Co2 Removal Using Imidazolium-Based Ionic Liquid -Aspen Plus Modelling Study
Published 2023“…Novel technologies that decrease the level of CO2 in our atmosphere are crucial for minimizing the potential risks associated with climate change, and immediate advancements are needed for such technologies to operate at global level. …”
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Identification of an amino-terminus determinant critical for ryanodine receptor/Ca2+ release channel function.
Published 2020“…The arrhythmia-linked R176Q mutation within the β8-β9 loop decreases N-terminus tetramerization but does not affect RyR2 subunit tetramerization or the N-terminus interaction with C-terminus. …”
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Biochemical and structural impact of two novel missense mutations in cystathionine β-synthase gene associated with homocystinuria
Published 2024“…In this study, we present the clinical and biochemical characterization of two novel CBS missense mutations that do not respond to pyridoxine treatment, namely c.689T > A (L230Q) and 215A > T (K72I), identified in a Chinese patient. …”
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Assessment of Dapagliflozin Effectiveness as Add-on Therapy for the Treatment of Type 2 Diabetes Mellitus in a Qatari Population
Published 2019“…The effectiveness of dapagliflozin in the management of type-2 diabetes mellitus (T2-DM) is an essential issue for establishing a basis for prescribing dapagliflozin. …”
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Host genetic variants potentially associated with SARS-CoV-2: A multi-population analysis
Published 2020“…Remarkably, Africans seem to carry extremely lower frequencies of SARS-CoV-1 susceptibility alleles, reaching to 32-fold decrease compared to other populations. Conclusion: Multiple genetic variants, which could potentially modulate SARS-CoV-2 infection, are significantly variable between populations, with the lowest frequency observed among Africans. …”
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The Cardiovascular Benefits of Empagliflozin, A Sodium Glucose Cotransporter Inhibitor: Is NHE1 a Viable Target?
Published 2020“…In our study, we examine the cellular interplay between NHE1 and SGLT1/SGLT2 in a non-diabetic in vitro model. We characterized H9c2 cardiomyoblasts stimulated with Angiotensin II (ANG II) 100nM in the presence and absence of EMPA (500nM) and measured cardiomyocyte hypertrophy and the expression of NHE1 and SGLT1/2. …”
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MOLECULAR FEATURES OF TRIPLE NEGATIVE BREAST CANCER STEM CELLS: A GENE EXPRESSION PROFILING ANALYSIS OF MDA-MB-231 CELLS
Published 2021“…Triple negative breast cancer (TNBC) is a chemoresistant subtype of female breast tumors. …”
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Elucidating the role of interacting residues of the MSH2-MSH6 complex in DNA repair mechanism: A computational approach.
Published 2019“…The present study aims to understand the impact of missense mutations in the interacting sites of the MSH2-MSH6 protein complex. MSH6 is unstable due to the disordered N-terminal domain. …”
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Synthesis and characterization of stir casted Cu-ZrO2-Graphite hybrid metal matrix composites for thermal management structures
Published 2022“…The properties of the prepared MMCs were found to be dependent on the reinforcements content present in the MMCs. ZrO2 and Graphite reinforcements were added (0.5–0.5, 1.0–1.0, 1.5–1.5 and 2.0–2.0 wt %) in the four composite samples prepared via stir casting. …”
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Results from the first culturally tailored, multidisciplinary diabetes education in Lebanese adults with type 2 diabetes: effects on self-care and metabolic outcomes
Published 2022“…This pilot-study tested the effect of culturally-tailored education targeting diabetes selfcare on glycemia and cardiovascular risk factors of Lebanese with type 2 diabetes mellitus (T2DM) (n = 27; Age: 61 ± 10 yrs, 59% males, HbA1c: 8.98 ± 1.38%). …”
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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
Published 2025“…Here, we report the engineering of a Bioluminescence Resonance Energy Transfer (BRET)-based SARS-CoV-2 main protease (Mpro) biosensor containing the Mpro N-terminal autocleavage sequence in tandem and a nanobody that shows an enhanced rate of Mpro-mediated proteolytic cleavage. …”
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Characterization of polysulfone/diisopropylamine 1-alkyl-3-methylimidazolium ionic liquid membranes: high pressure gas separation applications
Published 2020“…Thermogravimetric analysis measurement (TGA), differential scanning calorimeter (DSC), dynamic mechanical analysis, and the tensile properties of the membranes are studied in order to optimize the efficiency of separating CO2 from CO2/N2 mixture and CO2/CH4. TGA showed that pure PSF is a highly thermostable polymer, of which the 5% weight loss temperature is above 150 C. …”
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