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Quality improvement can decrease blood delivery turnaround time: Evidence from a single tertiary-care academic medical center
Published 2018“…The transport time significantly decreased from an initial majority of > 15 mins duration, to a majority of < 15 mins transport time after the second audit; there was a 50% improvement in 30 mins response time; and the percentage of requests processed in < 10 mins were significantly higher after the second audit. …”
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Design and analysis of PV fed high-voltage gain DC-DC converter using PI and NN controllers
Published 2022“…The modified converter contains mainly-one diode, two capacitors, and Coupled Inductor (CI). When the converter switch comes under active state two capacitors are discharged in series, similarly when the converter switch under inactive state those two capacitors are charged in parallel through the coupled inductor (CI) energy so, to get a high voltage at the converter output side. …”
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Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach
Published 2017“…Missense mutations of the HNF1A were retrieved from public databases and subjected to a three-step computational mutational analysis to identify the underlying mechanism. …”
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Biocorrosion behavior of biodegradable nanocomposite fibers coated layer-by-layer on AM50 magnesium implant
Published 2016“…The results showed that the AJS 3D membrane fiber layers, particularly the hybrid membrane layers containing a small amount of nHA (3wt.%), induce a higher biocorrosion resistance and effectively decrease the initial degradation rate compared with the neat AM50 coupon samples. …”
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The mitochondrial-related effect of the 905 nm photobiomodulation therapy on 50B11 sensory neurons
Published 2023“…In this study, a possible molecular mechanism of the 905 nm PBMT (0.25 W/cm2; 3, 6, 12, and 18 J/cm2, 5 Hz) analgesic effect was tested on 50B11 cells, by investigating its impact on mitochondria. …”
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Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2.
Published 2018“…Molecular docking analysis revealed a decrease in interaction between the protein and ATP in all the 3 mutations, and molecular dynamic simulations of 50 ns showed a loss of stability and compactness in the mutant proteins. …”
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In vitro effects of photobiomodulation therapy on 50B11 sensory neurons: evaluation of cell metabolism, oxidative stress, mitochondrial membrane potential (MMP), and capsaicin-indu...
Published 2021“…Calcium peak stimulated by capsaicin, the ligand of TRPV1 channel, was decreased in neurons pre-irradiated with the combination of the two wavelengths. …”
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A Reverse MultipleChoice Based mLearning System
Published 2018“…Thus, for every wrong attempt the performance is decreased by certain percentage.…”
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A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation...
Published 2019“…In addition, the change of glutamate to lysine at position 17 of AKT1 (E17K) was found to be highly predominant. An extensive two-step molecular dynamics (simple and complex) simulation (MDS) using GROMACS (GROningen MAchine for Chemical Simulations) was then initiated to analyze and understand the structural impact of the E17K mutation on the function of AKT1. …”
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Inner sphere oxidation of N,N′-ethylenebis(isonitrosoacetyleacetoneimine)copper(II) by N-bromosuccinimide in aqueous weakly acidic solutions
Published 2013“…The mechanism of the title reaction is consistent with an inner sphere mechanism in which a pre-equilibrium step precedes the electron transfer step. The overall rate law is represented by Eq. (2) where [CuIL]t and K 1 represent the total copper(II) complex concentration and the pre- equilibrium formation constant, respectively. d [CuL+]/dt = {(ko+k₁ [H+]) [SBr] [CuL]}/(1 + K₁ [SBr])…”
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Effect of BPA on CYP450s expression, and nicotine modulation, in fetal rat brain
Published 2022“…Fetal brains were isolated at gestational days GD14 and GD19, and protein expression was assessed by Western blotting. Results showed a BPA-induced significant decrease in CYP1B1 expression levels at GD14 (p = 0.001), and CYP19A1 (aromatase) expression at both mid- and late-stage development (p < 0.001). …”
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Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects
Published 2019“…This was associated with a marked decrease (50%) in the expression of detoxifying genes (NQO1 and GSTA1) with an increase in CYP1A1 mRNA expression, a cancer-activating gene. …”
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Coral reef resilience differs among islands within the Gulf of Mannar, southeast India, following successive coral bleaching events
Published 2021“…Overall, between 2005 and 2017 reefs had a simultaneous decrease in relative coral cover (avg. = ? …”
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MOLECULAR FEATURES OF TRIPLE NEGATIVE BREAST CANCER STEM CELLS: A GENE EXPRESSION PROFILING ANALYSIS OF MDA-MB-231 CELLS
Published 2021“…Triple negative breast cancer (TNBC) is a chemoresistant subtype of female breast tumors. …”
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