AKMT is important for invasion and egress, but not for parasite replication. by Aoife T. Heaslip (207534)

“…(C) The loss of AKMT results in a ∼90% decrease in invasion efficiency. The number of invaded parasites per field was counted in 10 fields each in 3 independent experiments. ***: P value <0.0001 (D) <i>Top</i>: Outline of A23187 induced egress assay. …”

Image_3_C2 IgM Natural Antibody Enhances Inflammation and Its Use in the Recombinant Single Chain Antibody-Fused Complement Inhibitor C2-Crry to Target Therapeutics to Joints Atten... by Nirmal K. Banda (1477765)

“…Total scores for histopathology were also 50% decreased (p < 0.0005) in CIA mice treated with C2-Crry. …”

Image_2_C2 IgM Natural Antibody Enhances Inflammation and Its Use in the Recombinant Single Chain Antibody-Fused Complement Inhibitor C2-Crry to Target Therapeutics to Joints Atten... by Nirmal K. Banda (1477765)

“…Total scores for histopathology were also 50% decreased (p < 0.0005) in CIA mice treated with C2-Crry. …”

Metabolomic and chemogenomic profiling. by Wesley C. Van Voorhis (191219)

“…Six of seven compounds (indicated in red) reported to target <i>Pf</i>ATP4 [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1005763#ppat.1005763.ref025" target="_blank">25</a>] showed a distinct metabolic response characterized by the accumulation of dNTPs and a decrease in hemoglobin-derived peptides. …”

DataSheet_1_Differences in Prostate Cancer Incidence and Mortality in Lower Saxony (Germany) and Groningen Province (Netherlands): Potential Impact of Prostate-Specific Antigen Tes... by Sanny Kappen (10889607)

“…Between 2003 and 2012, the average annual percentage change (AAPC) in PCa incidence rates did not change significantly in either Lower Saxony (−1.8%, 95% CI −3.5, 0.0) or Groningen (0.2%, 95% CI −5.0, 5.7). In contrast, the AAPC in mortality rate decreased significantly during the same time period in Lower Saxony (−2.5%, 95% CI −3.0, −2.0) but not in Groningen (0.1%, 95% CI −2.4, 2.6).…”

Supplementary Material for: Clinical Trial of Vadadustat in Patients with Anemia Secondary to Stage 3 or 4 Chronic Kidney Disease by Martin E.R. (3859435)

“…All subjects received low-dose supplemental oral iron (50 mg daily). The primary endpoint was the mean absolute change in hemoglobin (Hb) from baseline to the end of treatment. …”

Audio_2_Retroauricular/Transcranial Color-Coded Doppler Ultrasound Approach in Junction With Ipsilateral Neck Compression on Real-Time Hydroacoustic Variation of Venous Pulsatile T... by Xiuli Gao (2036302)

“…When the ipsilateral IJV was compressed, PT disappeared, as the mean velocity of mainstream sinus flow and diverticular vortex decreased by 51.2 and 50.6%, respectively. …”

Audio_1_Retroauricular/Transcranial Color-Coded Doppler Ultrasound Approach in Junction With Ipsilateral Neck Compression on Real-Time Hydroacoustic Variation of Venous Pulsatile T... by Xiuli Gao (2036302)

“…When the ipsilateral IJV was compressed, PT disappeared, as the mean velocity of mainstream sinus flow and diverticular vortex decreased by 51.2 and 50.6%, respectively. …”

sAPPα, sAPPβ and sAPP-Fc induce Egr1 expression. by Stéphanie Chasseigneaux (231744)

“…<p>(<b>A</b>) Real time PCR for each recombinant protein added to 1DIV neurons for 50 minutes shows a 2-fold increased expression of Egr1 compared to controls (Ctrl). …”

Variation in actuarial senescence does not reflect life span variation across mammals by Guillaume Péron (655312)

“…Variation in life span was increasingly driven by the intensity of actuarial senescence and decreasingly driven by prime-age adult mortality from small to large species because of changes in the elasticity of life span to these parameters, even if all the adult survival parameters consistently exhibited a canalization pattern of weaker variability among long-lived species than among short-lived ones. …”

Dataset for: The impact of exercise intensity on whole body and adipose tissue metabolism during energy restriction in sedentary overweight men and postmenopausal women by Jean-Philippe Walhin (3218595)

“…Insulinaemic responses to a standard glucose load decreased similarly at follow-up relative to baseline in VIG (∆ 8.6 ± 15.4 nmol.120min.l-1) and MOD (∆ 5.4 ± 8.5 nmol.120min.l-1; P<0.05). …”

PowerPoint Slides for: Clinical Trial of Vadadustat in Patients with Anemia Secondary to Stage 3 or 4 Chronic Kidney Disease by Martin E.R. (3859435)

“…All subjects received low-dose supplemental oral iron (50 mg daily). The primary endpoint was the mean absolute change in hemoglobin (Hb) from baseline to the end of treatment. …”

Audio_3_Retroauricular/Transcranial Color-Coded Doppler Ultrasound Approach in Junction With Ipsilateral Neck Compression on Real-Time Hydroacoustic Variation of Venous Pulsatile T... by Xiuli Gao (2036302)

“…When the ipsilateral IJV was compressed, PT disappeared, as the mean velocity of mainstream sinus flow and diverticular vortex decreased by 51.2 and 50.6%, respectively. …”

Audio_4_Retroauricular/Transcranial Color-Coded Doppler Ultrasound Approach in Junction With Ipsilateral Neck Compression on Real-Time Hydroacoustic Variation of Venous Pulsatile T... by Xiuli Gao (2036302)

“…When the ipsilateral IJV was compressed, PT disappeared, as the mean velocity of mainstream sinus flow and diverticular vortex decreased by 51.2 and 50.6%, respectively. …”

Knockdown of endogenous GpIbα in cancer cells reduces the frequencies of mitotic and cytokinesis defects, while overexpression of GpIbα in immortalized noncancer cells increases th... by Qian Wu (209382)

“…(B) Frequencies of mitotic and cytokinesis defects in HeLa cells were significantly decreased after GpIbα knockdown and enforced overexpression of a shRNA-resistant GpIbα (mGpIbα) restored most of the mitotic defects (n>100 cells per sample). …”

Datasheet1_Short-term exposure to ultrafine and fine particulate matter with multipollutant modelling on heart rate variability among seniors and children from the CorPuScula (coro... by Pascale Haddad (678636)

“…</p>Methods<p>CorPuScula (Coronary, Pulmonary and Sanguis) is a longitudinal, repeated-measure panel study conducted in 2000–2002 in Munich, Germany including 52 seniors (58–94 years old) with 899 observations and 50 children (6–10 years old) with 925 observations. …”

Datasheet1_Short-term exposure to ultrafine and fine particulate matter with multipollutant modelling on heart rate variability among seniors and children from the CorPuScula (coro... by Pascale Haddad (678636)

“…</p>Methods<p>CorPuScula (Coronary, Pulmonary and Sanguis) is a longitudinal, repeated-measure panel study conducted in 2000–2002 in Munich, Germany including 52 seniors (58–94 years old) with 899 observations and 50 children (6–10 years old) with 925 observations. …”

Table 1_Integrating comprehensive geriatric assessment into routine nursing care for older adults with type 2 diabetes: implementation fidelity and clinical outcomes.docx by Qinqin Sun (2942049)

“…Implementation fidelity was assessed using five validated dimensions yielding a composite score (mean 0.64, SD 0.19; range 0.28–0.94). …”

Data_Sheet_1_Divergent Effects of the N-Methyl-D-Aspartate Receptor Antagonist Kynurenic Acid and the Synthetic Analog SZR-72 on Microcirculatory and Mitochondrial Dysfunction in E... by László Juhász (9406387)

Image_1_Divergent Effects of the N-Methyl-D-Aspartate Receptor Antagonist Kynurenic Acid and the Synthetic Analog SZR-72 on Microcirculatory and Mitochondrial Dysfunction in Experi... by László Juhász (9406387)