Inhibition controls levels of pattern separation in granule cells through different neural codes. by Antoine D. Madar (6619286)

“…<p><b>(A)</b> Single GCs were recorded twice in response to the same input set (P10Hz, R = 0.76 at τ_w = 10 ms, shown in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1006932#pcbi.1006932.g001" target="_blank">Fig 1B</a>): First in normal aCSF, then under conditions of partial inhibitory block (aCSF + 100 nM gabazine, gzn), without changing any other parameter (i.e. same stimulation location and intensity). …”

Infectivity of <i>LdASS</i> mutants in the murine model. by Abul Hasan Sardar (573177)

“…In the <i>LdASS</i>^-/-/+ parasites, the IL-12 and IFN-γ were increased whereas IL-10 and TGF-β were decreased compared to WT parasites. Each measurement was performed in triplicate and data are expressed as the mean. …”

Effect of conversion from calcineurin inhibitors to everolimus on hepatitis C viremia in adult kidney transplant recipients by Larissa Sgaria Pacheco (5221397)

“…The mean eGFR was similar in both groups. Conclusion: Our study did not show viral load decrease after conversion to EVR with maintenance of antiproliferative therapy.…”

Effect of conversion from calcineurin inhibitors to everolimus on hepatitis C viremia in adult kidney transplant recipients by Larissa Sgaria Pacheco (5221397)

“…The mean eGFR was similar in both groups. Conclusion: Our study did not show viral load decrease after conversion to EVR with maintenance of antiproliferative therapy.…”

Effect of pazopanib on primary tumor growth of breast cancer and melanoma cell lines. by Brunilde Gril (202357)

“…P values are shown for the tumors in which the decrease in tumor size achieved significance (p<0.01) at a given dose of pazopanib. …”

Heme Oxygenase Isoform 1 Regresses Cardiomyocyte Hypertrophy Through Regressing Sodium Proton Exchanger Isoform 1 Activity by Sobh, Ahmed

“…Results: Our results showed a significant decrease in HO-1 mRNA expression in cardiomyocytes expressing active NHE1 (74.84 ± 9.19 % vs. 100 % normal NHE1 expression, p<0.05). …”
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Impact of community mask adherence and attitudes. by Dhaval Adjodah (11014160)

“…<p>Using a novel survey-based dataset of 847 thousand online Facebook survey respondents in 51 languages from 69 countries, we estimate that a 1% increase in community mask adherence is associated with a decrease of -0.61 [-0.82,-0.39] cases per 100K and a decrease of -0.035 [-0.040,-0.029] deaths per 100K. …”

HDAC inhibition blocks Glyc-Alb induced activation of HDACs. by Danielle Desjardins (735474)

“…<p>(A) ARPE19 cells showed a significant decrease in Ac-α-tubulin at 6 h post treatment of Glyc-alb (100 μg/mL) compared to administration of the same concentration of Alb. …”

Assessment of cell viability using quantification of lactate dehydrogenase (LDH) released by lesioned retinas treated with GJ blockers and openers. by Vera Paschon (306542)

“…On the other hand, we observed changes in LDH release when retinas were treated with the same drugs with a higher concentration (100 µM). (E) After incubating with CBX 100 µM for 4 h, we detected a significant decrease in the LDH release (−22%, <i>P</i><0.01). …”

Bcl-xL regulation of NF-κB RNAs: by Chi Zhang (9857)

“…<p>A: RNA was extracted from eggs and embryos at various stages and analyzed by RT-PCR (28 cycles); levels of RelA, Rel2, Rel3, RelB and Xp100 RNAs drop between stage 7 and 9 and, except for RelB, increase following gastrulation (stage 12/13). …”

FCF affects HIF-1α expression on the posttranslational level. by Dikla Vardi-Oknin (447319)

“…Quantitative real-time PCR analysis was done using primers for HIF-1α and cyclophilin B as control<i>. Columns</i>, means (n = 2); <i>bars</i>, SD. (<b>B</b>) PC-3 cells were treated with vehicle (control) and 100 μM FCF for 4 h under normoxia, and then CHX was added at a final concentration of 10 μg/ml for the indicated times. …”

The inhibition of mitochondrial respiratory chain complex activity by longer chain TPP⁺ compounds is dose dependent. by Jan Trnka (441288)

“…<p>Samples of rat skeletal muscle homogenate were incubated with various concentrations of decylTPP⁺ and dodecylTPP⁺ prior to the assay. <b>A, B, and C.</b> Complexes I, II, and III show a gradual decrease in activity proportionate with the dose of the TPP⁺ compounds. …”

Supplementary Material for: Carpal Tunnel Surgery as Proxy for Dialysis-Related Amyloidosis: Results from the Japanese Society for Dialysis Therapy by Hoshino J. (4145806)

“…<b><i>Methods:</i></b> The cohort consisted of 166,237 patients on dialysis (mean age 66.1 ± 12.4 years; mean dialysis vintage 7.2 ± 6.4 years) who could be followed for a year between 2010 and 2011. …”

<i>Mll2^Gdf9</i> cKO oocytes show loss of bulk H3K4me2 and H3K4me3 as well as H4 hyperacetylation. by Claudia V. Andreu-Vieyra (243666)

“…In contrast, a decrease in H3K4me2 (B) and H3K4me3 (C) levels was observed in <i>Mll2^Gdf9</i> cKO oocytes (B and C, lower panels) compared to controls (B and C, upper panels). …”

Preincubation with papaverine inhibits norepinephrine (NE) induced contractions in human saphenous vein. by Kyle M. Hocking (402156)

“…Panel B: Cumulative data obtained when the force was converted to stress and decrease in stress was converted to a percentage of the maximal initial KCl contraction which was set as 100%. …”

QTLs for yield and yield-components in F_{2: 3} and F_{2: 4} populations identified using composite interval mapping. by Qingzhi Liang (789537)

“…<p>* Common QTLs identified in the two generations</p><p>^a Additive effects; positive values of the additive effects indicate increase of traits from alleles of GX1135; negative values of the additive effects indicate decrease of traits from alleles of GX100-2</p><p>^b Dominance effects; positive values of the dominance effect indicate that heterozygotes have higher phenotypic values than the respective means of two homozygotes, and negative values indicate that heterozygotes have lower values than the means of the two homozygotes</p><p>^c Var%, phenotypic variation explained by a single QTL</p><p>QTLs for yield and yield-components in F_{2: 3} and F_{2: 4} populations identified using composite interval mapping.…”

Parasitemia titration results. by Paul Lebel (11250722)

“…<p>Logscale plots a-b,d-f contain shaded regions corresponding to nominal mean parasitemia plus or minus one standard deviation of the underlying Poisson distribution when counting N total cells, where N is varied from 100 up to 100,000 in roughly 3× increments. …”

Mechanisms involved in Sag-induced apoptosis. by Juliana Mundiñano (306020)

“…Data are expressed as the mean ± SD. *p<0.05. (E) Caspase-8 inhibitor decreases the loss of Δψm induced by SEB. …”

Model for penetratin-phospholipid membranes interactions. by Ofelia Maniti (247890)

“…<p>A) The association of penetratin with PG membranes results in the conformational change of the peptide with α-helix and β-sheet contributions and a decrease in membrane fluidity. B) With PC membranes, the peptide associates in a two step processes but remains quite unstructured and does not change notably the fluidity of the membrane. …”

Effects of diabetes mellitus and systemic arterial hypertension on elderly patients' hearing, by Laurie Penha Rolim (6073727)

“…ANOVA and Kruskal-Wallis statistical tests were used, with a significance level set at 0.05. Results: When comparing the mean annual increase in the auditory thresholds of the A1 with the A2 assessment, considering each study group and its respective control, it can be observed that there was no statistically significant difference for any of the frequencies for the diabetes mellitus group; for the systemic arterial hypertension group, significant differences were observed after 4 kHz. …”