Efficacy and selectivity of the shSNP <i>in vitro</i>. by Valérie Drouet (3179907)

“…Levels of the chimeric <i>HTT</i> mRNA were normalized to β-Actin and are reported as mean percentages relative to the control condition (set at 100%) ± SEM (n = 3–5). …”

Chordoma preclinical models are insensitive to BAF complex inhibitor FHD-286, alone or in combination with gemcitabine by Chordoma Foundation (4391989)

“…A panel of 4 chordoma cell lines were seeded in a white-walled 96-well plate so that at the start of treatment, 36 hours after plating, the confluence was 15%. …”

Self-limiting of the gTLR9 signaling by <i>gTlr9</i> alternative splicing. by Frank Fang-Yao Lee (2210863)

“…DRB pre-treatment (0 h) led to slight increase of <i>9A</i> (<b>B</b>) and decrease of <i>9B</i> (<b>C</b>) (Cf. the two gray bars vs. white and black bars). …”

Feijoa F3 does not activate autophagy or inhibit NF-κB activity in autophagy defective HCT116 cells. by Noha Ahmed Nasef (760610)

“…A percentage of greater than 100 shows increased inflammatory response in the presence of the ligand when compared to media (no treatment); and a percentage of less than 100 suggests a decrease in the inflammatory response in the presence of the ligand when compared to media (no treatment) meaning that a condition has inhibited NF-κB signaling. …”

The effector functions of CHK-152 contribute to protection <i>in vivo</i>. by Pankaj Pal (404355)

“…Comparison of binding of ch-CHK-152 and ch-CHK-152 N297Q to FcγR (CD16A, 500 nM; CD32A, 100 nM; and CD64, 100 nM) or C1q (50 nM), as measured by surface plasmon resonance. …”

Selective loss of macrophage subpopulations in lymphoid tissue of <i>Csf1rko</i> rats. by Dylan Carter-Cusack (20624041)

“…Positive logFC indicates an increase in expression in <i>Csf1rko</i> animals, while negative logFC indicates a decrease in expression in <i>Csf1rko</i> animals. …”

Effect of 3BrP on morphology, cell number, viability, proliferation and pluripotency. by Ana Sofia Rodrigues (491559)

“…Cells stained green were counted as live, while PI positive cells were counted as dead. 100 cells were counted per condition for a total of n = 8 independent experiments, results are expressed as means ± SEM for 30 experiments. …”

Deletion of RBPJK enhances cell spontaneous differentiation in regular MSC culture. by Xifu Shang (784529)

“…<p>Mesenchymal stem cells were infected with Control shRNA(Co) or RBPJK shRNA (shRBPJK) lentivirus before being harvested for alkaline phosphatase (ALP) staining, western blot, RT-PCR analysis and BrdU ELISA. (A) Western Blot showed a significant decrease of RBPJK protein expression at day 3 and 14 following shRBPJK lentiviral infection. …”

Myelin and myelin proteins are marginally reduced in the brain of <i>Syn1Cre; Galc flox/−</i>. by Conlan Kreher (13001753)

“…Scale bar = 100 μm. (<b>E</b>) Quantification of PLP level, measured by averaged integrated signal intensity, reveals a trend of reduction in the mutant brain. …”

Figure 4, supplementary figure 6 by Kristen Pleil (11084931)

“…</b>a) Proportion of responder categories during 10-minute E2 wash on across E2 doses (0.01, 1, 10, 100, 1000 nM) for frequency (top) and amplitude (bottom). b) Raw average frequency (top) and amplitude (bottom) during baseline, E2 wash on, and washout for each cell. c) Maximum % change from baseline for cells categorized as increased and decreased during E2 wash on for frequency (top) and amplitude (bottom). …”

Combined expression of pTFs promotes transdifferentiation efficiency, however only their sequential expression increases β-cell maturation. by Dana Berneman-Zeitouni (519463)

“…<p>Cultured adult human liver cells were infected with <i>Ad-CMV-Pdx1</i> (1000 MOI), <i>Ad-CMV-Pax-4</i> (100 MOI) and <i>Ad-CMV-Mafa</i> (10 MOI) together or in a sequential manner as summarized in (A) (treatments B–E) or with control virus (<i>Ad-CMV-β-gal</i>, 1000 MOI, treatment A), and analyzed for their pancreatic differentiation six days later. …”

Supplemental Figure 1 by lsimo2@lsuhsc.edu lsimo2@lsuhsc.edu (6704447)

“…There was a main effect of OVX to decrease HOMA-β at study endpoint. …”

The effects of FRLFE on the NF-κB-dependent transcription of the <i>iNOS</i> gene. by Ryota Yamanishi (547533)

“…<p>(<b>A</b>) FRLFE decreases the iNOS promoter activity. …”

Table1_Fibrates for the Treatment of Primary Biliary Cholangitis Unresponsive to Ursodeoxycholic Acid: An Exploratory Study.docx by Guilherme Grossi Lopes Cançado (10373078)

“…</p><p>Results: In total, 27 patients (100% women, mean age 48.9 ± 9.2 years) with PBC were included. …”

Polarity independent brain structures form from stem cells that have progressed through S-phase during the first 16 hours of regeneration. by Deborah J. Evans (195583)

“…<p>(A) Proliferation assay of single and double amputated trunk pieces at different times of regeneration indicate double cuts produce a decrease in the amplitude of both characteristic mitotic peaks and a delay in the first mitotic peak (mean number of mitotic cells, error bars are +/− 1 SEM of the mean, n = 12 at each time point). …”

Biochemical characterization of the endolysins of the lactococcal phages P008, c2, 1358, and P335. by Frank Oechslin (4825476)

“…The color gradient indicates the percent of decrease in absorbance measured over time. Values are means and standard deviations from triplicates (<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3001740#pbio.3001740.s016" target="_blank">S1 Data</a>). …”

State of the mixture distribution in response to an ABA- sequence, shown at several time points. by Dana Barniv (837537)

“…(e) <b><i>π</i>₁, <i>π</i>₂</b>, plotted in log scale. The inset illustrates the fast oscillations of <b><i>π</i>₂</b>, where each point indicates one time step; notice there are two down steps after each up step, because A occurs twice after every occurrence of B in the ABA- sequence. …”

Viral ORF57 inhibits eIF2α phosphorylation. by Nishi R. Sharma (4543936)

“…The error bar indicates mean ± SD (n = 3). (D-E) KSHV lytic infection in BCBL-1 cells does not increase eIF2α phosphorylation, but rather decrease arsenite-induced eIF2α phosphorylation. …”

Proliferation of CTS-treated cells. by Rebecca J. Clifford (497197)

“…<p>A) Normal MCF10A cells exhibited a concentration-dependent decrease in BrdU incorporation (proliferation) when treated with 500 nM ouabain, 50 nM bufalin or 100 nM bufalin for 2 hours (p<0.01). …”

The CCDC66 depletion disrupts normal tissue organization and signaling in 3D and 2D cultures. by Jovana Deretic (13113617)

“…Mean cilia percentage is 59.78 for shControl and 53.80 for shCcdc66, with a fold change decrease of 0.90. …”