Co-immunoprecipitation of CFTR, HSPs, VCP, and HDAC6 in the N1303K and S1235R cell lines treated or untreated with the compounds. by Daniele Rapino (506785)

“…(<b>B)</b> Graphs were adjusted for the total amount of CFTR detected in the immunoprecipitated samples (the y axis shows the ratio between each sample and the total amount of CFTR in that sample. Controls are set as 100% binding). The data show that treatment with compounds C3+C4 at 5 μM is able to significantly decrease the amount of the HSPs VCP and HDAC6 that bind to the mutants. …”

Retinoic acid attenuates reductions of phospho-Akt and phospho-Bad expression due to MCAO damage. by Ju-Bin Kang (16021324)

“…Scale bar = 100 μm.</p>…”

Effect of exercise and PCB on levels of IL-6 in wound tissue at day 3 and day 5 post-wounding. by Mahesh R. Pillai (9292269)

“…<p>In not exercised animals, on Day 3, there appears to be no difference in the means of IL-6 concentrations across PCB doses. However, Day 3, exercised animals demonstrate a pattern of reduced IL-6 concentrations with PCB 500 and PCB 1000, but increased with PCB 100 administration as compared to PCB 0. …”

Spinal cord staining with GFAP. by Dalal G. Al-Adwani (8190696)

“…<p><b>A:</b> Representative photomicrographs (100x objective) of the ipsilateral ventral grey horn of L3-L6 spinal cords sections from all groups immunostained for GFAP (GFAP (GA-5): sc-58766, Mouse Monoclonal–Santa Cruz Biotechnology) at week 3 <b>(A1, A3, A5, A7 and A9)</b> and week 6 <b>(A2, A4, A6, A8 and A10)</b> following nerve crush injury. …”

Bircarb_CO2_crocodilian_hemoglobin by Naim M. Bautista (9569894)

“…We experimentally confirmed the same mode of allosteric regulation in the Hbs of a phylogenetically diverse set of other caiman, alligator, and crocodile species, suggesting that this novel allosteric property evolved >80-100 million years ago in the common ancestor of modern crocodilians. …”

Carcass characteristics of lambs fed diets with inclusion of sugar cane dry yeast by José Teodorico de ARAÚJO FILHO (6127064)

“…The inclusion of sugar cane dry yeast did not affect the color of thelongissimus dorsi and kidney fat, while for rib eye area, renal pelvic fat and body condition, whereas if included sugar cane dry yeast there was a decrease of these variables. Gross margin decreased by lamb as it included the sugar cane dry yeast in the diet. …”

Image_4_Ascorbic Acid-Induced Photosynthetic Adaptability of Processing Tomatoes to Salt Stress Probed by Fast OJIP Fluorescence Rise.TIF by Xianjun Chen (5711882)

“…Lower K- and L-bands and higher I-band were detected on the OJIP transient curves compared, respectively, with salt-stressed plants with and without LYC. AsA application also significantly increased the values of normalized total complementary area (S_m), relative variable fluorescence intensity at the I-step (V_I), absorbed light energy (ABS/CS_m), excitation energy (TR_o/CS_m), and reduction energy entering the electron transfer chain beyond Q_A (ET_o/CS_m) per reaction centre (RC) and electron transport flux per active RC (ET_o/RC), while decreasing some others like the approximated initial slope of the fluorescence transient (M_o), relative variable fluorescence intensity at the K-step (V_K), average absorption (ABS/RC), trapping (TR_o/RC), heat dissipation (DI_o/RC) per active RC, and heat dissipation per active RC (DI_o/CS_m) in the presence or absence of LYC. …”

Image_3_Ascorbic Acid-Induced Photosynthetic Adaptability of Processing Tomatoes to Salt Stress Probed by Fast OJIP Fluorescence Rise.TIF by Xianjun Chen (5711882)

“…Lower K- and L-bands and higher I-band were detected on the OJIP transient curves compared, respectively, with salt-stressed plants with and without LYC. AsA application also significantly increased the values of normalized total complementary area (S_m), relative variable fluorescence intensity at the I-step (V_I), absorbed light energy (ABS/CS_m), excitation energy (TR_o/CS_m), and reduction energy entering the electron transfer chain beyond Q_A (ET_o/CS_m) per reaction centre (RC) and electron transport flux per active RC (ET_o/RC), while decreasing some others like the approximated initial slope of the fluorescence transient (M_o), relative variable fluorescence intensity at the K-step (V_K), average absorption (ABS/RC), trapping (TR_o/RC), heat dissipation (DI_o/RC) per active RC, and heat dissipation per active RC (DI_o/CS_m) in the presence or absence of LYC. …”

Image_1_Ascorbic Acid-Induced Photosynthetic Adaptability of Processing Tomatoes to Salt Stress Probed by Fast OJIP Fluorescence Rise.TIF by Xianjun Chen (5711882)

“…Lower K- and L-bands and higher I-band were detected on the OJIP transient curves compared, respectively, with salt-stressed plants with and without LYC. AsA application also significantly increased the values of normalized total complementary area (S_m), relative variable fluorescence intensity at the I-step (V_I), absorbed light energy (ABS/CS_m), excitation energy (TR_o/CS_m), and reduction energy entering the electron transfer chain beyond Q_A (ET_o/CS_m) per reaction centre (RC) and electron transport flux per active RC (ET_o/RC), while decreasing some others like the approximated initial slope of the fluorescence transient (M_o), relative variable fluorescence intensity at the K-step (V_K), average absorption (ABS/RC), trapping (TR_o/RC), heat dissipation (DI_o/RC) per active RC, and heat dissipation per active RC (DI_o/CS_m) in the presence or absence of LYC. …”

When there are no group events, mutations cause community extinction, but group-level events prevent this fate, as exemplified by the three archetypal modes of fragmentation. by Gil J. B. Henriques (11426697)

“…<b>A</b>: Example replicate with no group events (i.e., no group fission and extinction), showing fast initial rise in the number of mutants and the consequential decrease in the total cell number, resulting in extinction. …”

7-Valent Pneumococcal Conjugate Vaccination in England and Wales: Is It Still Beneficial Despite High Levels of Serotype Replacement? by Yoon Hong Choi (52781)

“…</p> <h3>Conclusion</h3><p>Our model suggests that PCV7 vaccination could result in a decrease in overall invasive pneumococcal disease, particularly in children, even in an environment of rapid replacement with non-PCV7 serotypes within 5 years of vaccine introduction at high coverage.…”

Loss of PLZF Expression in Prostate Cancer by Immunohistochemistry Correlates with Tumor Aggressiveness and Metastasis by Guang-Qian Xiao (711983)

“…This study aimed to investigate the expression of PLZF by immunohistochemistry in different grade as well as metastatic PCa and to correlate the alteration of PLZF expression with PCa aggressiveness. We studied a total of 83 primary PCa from biopsies, 43 metastatic PCa and 8 paired primary and metastatic PCa from radical prostatectomies with lymph node dissection. …”

The ROP2-RIC4 pathway inhibits PIN1 endocytosis through the promotion of the accumulation of cortical actin filaments. by Shingo Nagawa (173932)

“…Compared to WT cells, formation of vesicles (arrowheads) and decrease of PM signal were accelerated in <i>ric4-1</i> cells as in <i>rop4 R2i</i> cells (<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1001299#pbio-1001299-g001" target="_blank">Figure 1D</a>). …”

Investigating the expression of several bone markers in mineralizing 4T1 cells using real-time RT-PCR. by Rachel F. Cox (148193)

“…<p>(A) Alizarin red S and von Kossa staining of 4T1 cells after 28 days as viewed under a light microscope at 100× magnification (n = 3). …”

PGRN knockdown results in reduced motor axon outgrowth. by Angela S. Laird (360986)

“…<p>A) Knockdown of <i>grna</i>, by morpholino targeted to both the start codon (ATG) and 5′UTR region of zebrafish PGRN sequence, produced a dose dependent decrease in axonal length compared to mismatch Control MO injected embryos.…”

Data_Sheet_1_The combined impact of redcedar encroachment and climate change on water resources in the Nebraska Sand Hills.docx by Yaser Kishawi (12959564)

“…For the period 2051-2099, the projected P and ET_a are expected to decrease by 8 and 32% while R and D are expected to increase by 140.2 and 40%. …”

Statistical comparisons for the joint entropy measurements obtained from individual subjectspresented in Tables 1–3. by Vladímir de Aquino Silveira (513285)

“…In all frequencies there was a trend for joint entropy to decrease when contrast was increased, but this reached the level of statistical significance only for the comparison between 5% and 100% contrasts (p<0.05; One-Way ANOVA, Tukey Multiple Comparison Test). …”

Propagation of GABA-induced hyperpolarization at the axon regulates AP generation. by Yang Xia (104600)

“…Right, group data showing a decrease in the mean frequency of APs after GABA iontophoresis at the axon trunk. **, P<0.01, paired t-test. …”

High mutation rates limit evolutionary adaptation in <i>Escherichia coli</i> by Kathleen Sprouffske (82909)

“…Here, we study how up to 100-fold increases in <i>Escherichia coli’s</i> genomic mutation rate affect adaptive evolution. …”

Influence of the environment on microsphere movement. by Valery Shalatonin (12666750)

“…A slow decrease of microsphere motion began within approximately 20–25 seconds, and by the end of the video (100 seconds later) their motion became very slow.…”