MMP3 induced mitochondrial ROS regulate the Nox1 expression in 6-OHDA treated N27 cells. by Dong-Hee Choi (617376)

“…Apo: apocynin, a Nox inhibitor; GKT: GKT137831, a Nox1 selective inhibitor; AA, antimycin A (100 µM); FCCP, an oxidative phosphorylation uncoupler (100 nM), Results are presented as the mean ± SEM, n = 8. ** p<0.01, ***p<0.001 vs. nontreated control; # p<0.05, ## p<0.01, ### p<0.001 vs. 6-OHDA control. …”

Data_Sheet_1_Polygenic Risk Score for Early Prediction of Sepsis Risk in the Polytrauma Screening Cohort.docx by Hongxiang Lu (2947089)

“…Genetic variants with mean decrease accuracy (MDA) > 1.0 by random forest algorithms were selected to construct the multilocus wGRS. …”

Image_1_Polygenic Risk Score for Early Prediction of Sepsis Risk in the Polytrauma Screening Cohort.TIF by Hongxiang Lu (2947089)

“…Genetic variants with mean decrease accuracy (MDA) > 1.0 by random forest algorithms were selected to construct the multilocus wGRS. …”

GBE treatment improved mitochondrial capacity. by Virginie Rhein (243241)

“…Two-way ANOVA revealed also a significant effect of GBE (100 µg/ml; 24 h) on total O₂ consumption. …”

METIS partitioning of lj4m: Average time consumption with different <i>M</i> and Δ. by Guohao Dou (17067781)

“…<p>Like <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0291871#pone.0291871.g006" target="_blank">Fig 6</a>, we see a decrease in total time consumption as <i>M</i> increases and as Δ increases. …”

Antibodies of the PGT121 family compete with sCD4, but not PGV04, for binding to gp120 in solution and on the cell-surface. by Jean-Philippe Julien (135641)

“…Negative values indicate a decrease in binding affinity of sCD4 or PGV04 in the presence of PGT121 antibodies, positive values represent an increase in binding affinity and a value of ∼1 represents no effective change in binding affinity. …”

Arginine-dependent mRNA destabilization. by Tamar Ben-Zvi (3175077)

“…Putrescine can be produced from ornithine via <i>speC</i> and <i>speF</i> encoding a constitutive and inducible ornithine decarboxylase, respectively or from arginine in two steps via <i>speA</i> and <i>speB</i> encoding arginine decarboxylase agmatine ureohydrolase respectively. …”

MOESM5 of The Study of Enhanced High-Intensity Focused Ultrasound Therapy by Sonodynamic N2O Microbubbles by Xiaowen Zhong (1465861)

“…The optical density of each well was measured at 450 nm with a Bio-Tek microplate reader. Cell viability of the control group was defined as 100%. …”

Contribution of anti-gp120 antibodies to the overall neutralizing activity of HIV+ plasmas. by Iliyana Mikell (120166)

“…<p>(A) Log10 decrease in neutralizing activity caused by the elimination of anti-gp120 antibodies, and (B) Log10 decrease in neutralizing activity of plasmas in the presence of D368R. …”

Gemcitabine and ATR inhibitor synergism and effects on the cell cycle and DNA damage in U-CHCF365 and UM-Chor1 (Batch 1) by Chordoma Foundation (4391989)

“…</p><p><br></p><p dir="ltr">The following panels were treated according to panel A. The concentrations of gemcitabine and elimusertib used for U-CHCF365 were 5nM and 100nM, respectively, with those doses combined in the combination. …”

Gemcitabine and ATR inhibitor synergism and effects on the cell cycle and DNA damage in CH22 and U-CH17PII (Batch 2) by Chordoma Foundation (4391989)

“…</p><p><br></p><p dir="ltr">The following panels were treated according to panel A. The concentrations of gemcitabine and elimusertib used for CH22 were 5nM and 100nM, respectively, with those doses combined in the combination. …”

Supplementar material of the manuscript  The Effects of Lipoic Acid on Yolk Nutrient Utilization, Energy Metabolism, and Redox Balance over Time in <em>Artemia</em> sp.  by Juan Rafael Buitrago Ramírez (6244172)

“…ETS activity was positively regulated by the addition of LA, with the most significant effects at concentrations of 5.0 and 10.0 µM at 12 and 24 h. For ETS activity, treatments with LA presented the highest values at 24 h, a period when ROS production decreased significantly, for the treatment with 10.0 µM. …”

Dynamics of the Ca²⁺ depletion waves. by Mitra Esfandiarei (280455)

“…<p><b>A)</b> Heat map generated from the time-lapse fluorescence microscopy movie (10 s intervals) of rat SMCs treated with ET-1 (100 nM) in nominally free extracellular Ca²⁺, showing that the SR depletion wave expands in a near circular fashion in both directions of the scan line (dotted white line). …”

TRAIL pathway and the gene-gene interaction. by Yin-Ping Zhang (260509)

“…<p>The binding of TRAIL to TRAILR2 may induce the apoptosis of osteoclast. Increased c-FLIP levels may decrease the apoptosis of Osteoclast. …”

Supporting main Fig 2. by Jyoti Tanwar (2230597)

“…<p><b>MCU positively regulates melanogenesis while MCUb negatively controls melanogenesis. (A)</b> Quantitation of resting mitochondrial Ca²⁺ with CEPIA2mt in siNT control and siMCUb B16 cells stimulated with 100 μm histamine. …”

C2CD3 regulates spatial organization of centriole architecture. by Eloïse Bertiaux (5309927)

“…For CEP162-positive centrioles: siCTRL = 100% ± 0, siC2CD3 = 50.83% ± 4.31. Overall CEP162 fluorescence decreased in siC2CD3 (<i>n</i> = 31, 1.47 ± 0.39 AU.) vs. siCTRL (<i>n</i> = 35, 1.68 ± 0.51 AU), unpaired <i>t</i> test *** <i>P</i> value = 0.0008. …”

sFRP-3 binds EGF <i>in vitro</i>. by Raffaella Scardigli (49421)

“…Absorbance scanning from emission value 505 nm to 540 nm of EGFAlexa488 (green curve). A decreasing of the emission peak (517 nm) is shown in relation to EGFAlexa488/sFRP-3 interaction (red curve). …”

CPZ pretreatment inhibits cleaved caspase-3 expression in rat brains after ethanol exposure. by Jing Wu (54032)

“…All three doses of CPZ result in a significant decrease of the cleaved caspase-3 levels compared with ethanol group.…”

Characterization of 599 peptide-mediated RNAi responses in oral cancer cells. by Liliana Cantini (453377)

“…(<b>B</b>) Western blot analysis of CIP2A protein knockdown in SCC-25 oral cancer cells 48 hours post-treatment with 599 peptide alone (5 µM) or complexed at a 50∶1 peptide-to-siRNA molar ratio to either siNT (100 nM) or decreasing concentrations of siCIP2A. …”

TGFβ signaling promotes NDR1 turnover. by Isabelle Pot (427025)

“…Data are presented as the mean+SEM (n = 4) of percent decrease in protein abundance of NDR1 in NMuMG cells in response to TGFβ. …”