Effect of broad-spectrum potassium channel blockers on evoked DA overflow. by Philippe Martel (350692)

“…(E) After a 30 min application of 100 µM 4-AP, 1 µM ConoTX was applied and caused a ∼ 90% decrease in evoked DA release. …”

Effect of the overexpression of Mfn2 or the truncated Mfn2 mutant on mitochondrial function in GCDCA-treated L02 cells. by Yongbiao Chen (418836)

“…The results are expressed as a percentage of the control value, which was set at 100%. …”

Effects of hormone therapy and high-fat diet on microglia in female mice. by Amy Christensen (4062937)

“…Scale bar in (A) measure 20 μm and in (D) measures 100 μm.</p>…”

No expression of eMHC in RFs and attenuation of ongoing muscle regeneration in aged <i>mdx</i> and <i>mdx52</i> mice. by Yusuke Echigoya (437052)

“…Values are mean ± S.D. (<i>n</i> = 3–6 mice per group). A significant decrease in the number of eMHC-positive fibers is found only at 18<b> </b>months old in <i>mdx</i> mice (**<i>P</i><0.01 compared to 2<b> </b>months old, †<i>P</i><0.05 compared to 6 and 12<b> </b>months old). …”

Effects of Gu-4 on survival and expression profiles of TNF-α and IL-10 in septic mice. by TingTing Yan (5652595)

“…Gu-4 administration significantly reduced LPS-induced mortality at the doses of 0.88, 1.06, 1.27 and 1.53 mg/kg. *: p<0.05 indicates a significant decrease in mortality by Gu-4 treatment versus saline treatment as determined by log-rank test. β-lactose or dexamethasone (Dex) did not produce significant improvement in survival. …”

Cartilage and subchondral bone degeneration scores at 7 and 12 wks after the start of the experiment. by Junya Sakamoto (4286575)

“…<p><b>A:</b> a, b and c; Representative toluidine blue staining of each group at 7 wks after the start of experiment. …”

Chemical composition, hygiene characteristics, and coagulation aptitude of milk for Parmigiano Reggiano cheese from herds yielding different milk levels by Piero Franceschi (10446722)

“…Increased milk production was associated with a reduction in milk fat content (from 3.54 in the L-group milk to 3.29 g/100 g in the H-group milk). …”

Secreted Amyloid Precursor Protein β and Secreted Amyloid Precursor Protein α Induce Axon Outgrowth In Vitro through Egr1 Signaling Pathway by Stéphanie Chasseigneaux (231744)

“…</p> <h3>Methodology/Principal Findings</h3><p>Final concentrations of 50 to 150 nM bacterial recombinant sAPPα or sAPPβ added to primary neuronal cultures after 1 day in vitro decreased cell adhesion 24 hours later and primary dendrite length 96 hours later. 150 nM sAPPα and sAPPβ induced a similar increase of axon outgrowth, although this increase was already significant at 100 nM sAPPα. …”

<i>Ezh2^fl/fl:Nkx2.5-cre+</i> mice exhibited hypoplastic endocardial cushions. by Li Chen (5749)

“…<p>(<b>A–B′</b>) H&E staining revealed a decrease in the cell population in the EC region of <i>Ezh2</i> null hearts compared with that of control (arrows) at E10.5. …”

Hv1 increases colorectal cell migration and invasion. by Yifan Wang (380120)

“…<p>A, B and C, migration kinetics of SW620 (A), SW480 (B) and HT29 (C) assayed by wounded monolayer model. nc, cells transfected with the negative control (a, b, c, d and e in left panels); si, cells transfected with siRNA (f, g, h, i and j in left panels); and Zn²⁺, cells cultured at a final concentration of 100 µM ZnCl₂ (k, l, m, n and o in left panels). …”

Effect of ACE inhibitors on the local conformation of blood ACE in uremia. by Maxim N. Petrov (118931)

“…<p><b>A</b>. The ratio of ACE activities precipitated from the citrated plasma of uremic patients by mAbs 1G12 and 9B9 (1G12/9B9 ratio) and from pooled plasma from healthy volunteers in the presence of enalaprilat (100 nM) – red bars and without the inhibitor – grey bars. …”

Cell death and JNK activation in SH-SY5Y cells stimulated with H₂O₂ overnight or for 3 h. by Marco Feligioni (287395)

“…A concentration dependent increase in cell death (80–100%) is observed following overnight H₂O₂ stimulation. …”

S10 Fig - by Niranjan Sarpangala (12837428)

“…We simulated 200 cargo runs (without rotational diffusion) for N = 16 [ATP] = 2 mM case and recorded the value of the number of bound motors at a sampling rate of 100 s⁻¹. With this data, we identified all the <i>n</i> bound motors to <i>n</i> + 1 bound motor transitions, calculated the mean time for such transitions, and then the mean rate (1/meantime). …”

Genetic ablation of <i>C1ql1</i>-expressing OPCs prevents myelination in the forebrain without affecting axogenesis. by Shayan Moghimyfiroozabad (19066182)

“…Quantification of the thickness of the fiber bundles in the corpus callosum and the intensity of NF in the cortex shows a small decrease in the thickness of the lateral part of the corpus callosum, probably explained by reduced myelination. …”

Proteasome function is required for AMPA-induced depotentiation of synaptosomes. by Amadou T. Corera (372197)

“…LTP was induced in synaptosomes and AP5 (100 µM) was added as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0006021#pone-0006021-g002" target="_blank">figure 2F</a>. …”

Tonotopic differences in outer hair cell properties. by Eric Wersinger (238206)

“…Representative records of currents evoked by a series of voltage steps (100 ms in duration) from −131 mV to 49 mV in 10 mV increments (with an interpulse holding potential of −81 mV) show an increase in outward current (at 49 mV) from 2.08±0.09 nA in outer hair cells from apical regions (n = 25, F) to 7.24±0.4 nA in outer hair cells from basal regions (n = 23 basal, G). …”

EWS downregulation affects apoptosis, cell cycle and proliferation. by Sujitha Duggimpudi (699551)

“…<p><b>A</b>. Decrease in the relative mRNA levels of FBXW7 upon knocking down EWS. …”

Mapping changes in patterning after inhibition of Notch activity. by Matthew French (13007466)

“…Note the statistically significant decrease in the CLE and NSB like regions TBX6. Data for Fig 7 (D–F): Data file 3, <a href="https://doi.org/10.5281/zenodo.15802710" target="_blank">https://doi.org/10.5281/zenodo.15802710</a>.…”

MAGLi 432 treatment after LPS challenge does not reduce BBB permeability and inflammatory cytokine expression in the cortex. by Alicia M. Kemble (8555517)

“…<p><b>(A)</b> Immunofluorescence micrographs of 100-μm cortical sections from mice (n = 6) injected with 70-kDa FITC-dextran following LPS challenge and treatment (<b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0268590#pone.0268590.g003" target="_blank">Fig 3A</a></b>) stained with an anti-CD31 (PECAM-1) antibody (orange) to label blood vessels and DAPI as a nuclear stain (blue). …”

Burst stimulation. by Damian M. Herz (16007088)

“…In all patients, DBS was given in bursts of varying duration (mean 250 ms). Between stimulation bursts was an approximately 500-ms long pause (mean 150 ms interval + ramping up and down each lasting ca. 175 ms on average = 500 ms, see also <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002140#pbio.3002140.s008" target="_blank">S1 Table</a>). …”