Data Supplement from Epigenetic Targeting of Ovarian Cancer Stem Cells by Yinu Wang (14844702)

“…Low dose SGI-110 induces sustained cell cycle arrest on OC cells. A. Time-course cell cycle analysis of platinum sensitive A2780 ovarian cancer cells and platinum resistant A2780_CR5 and SKOV3 OC cells after 72 hour daily treatment with low dose SGI-110 (100nM). …”

Comparison of various inducer treatments on physiological and biochemical parameters in plants under drought conditions, relative to both drought-stressed and well-watered control... by Shelina Akter Sheuli (22446598)

“…Each parameter, such as chlorophyll, carotenoids, H₂O₂, proline, peroxidase (POD), glutathione S-transferase (GST) activity, and RWC, is normalized to the control, set at 100. Values exceeding 100 indicate an increase relative to the control, suggesting enhanced effects under treatment, while values below 100 signify a decrease, indicating reduced effectiveness compared to the control.…”

Comparison of various inducer treatments on physiological and biochemical parameters in plants under normal conditions, relative to well-watered control plants. by Shelina Akter Sheuli (22446598)

“…Each parameter—chlorophyll, carotenoids, H₂O₂, proline, peroxidase (POD), and glutathione S-transferase (GST) activity is normalized to the control, set at 100. Values exceeding 100 indicate an increase relative to the control, suggesting enhanced effects under treatment, while values below 100 signify a decrease, indicating reduced effectiveness compared to the control.…”

General Methodology to Optimize Damping Functions to Account for Charge Penetration Effects in Electrostatic Calculations Using Multicentered Multipolar Expansions by Araken S. Werneck (2458621)

“…This methodology is based in the optimization of a damping parameter set using a two-step fast local fitting procedure and the ab initio (Hartree−Fock/6-31G** and 6-31G**+) electrostatic potential calculated in a set of concentric grid of points as reference. …”

Genetic and Metabolomic Dissection of the Ergothioneine and Selenoneine Biosynthetic Pathway in the Fission Yeast, <i>S. pombe</i>, and Construction of an Overproduction System by Tomáš Pluskal (475361)

“…In this study we report the genes forming the two-step ergothioneine biosynthetic pathway in the fission yeast, <i>Schizosaccharomyces pombe</i>. …”

Comprehensive Functional Annotation of 77 Prostate Cancer Risk Loci by Dennis J. Hazelett (517336)

“…To aid the identification of these enhancers, we performed genomewide ChIP-seq for H3K27-acetylation, a mark of actively engaged enhancers, as well as the transcription factor TCF7L2. We analyzed in depth three variants in risk enhancers, two of which show significantly altered androgen sensitivity in LNCaP cells. …”

General Methodology to Optimize Damping Functions to Account for Charge Penetration Effects in Electrostatic Calculations Using Multicentered Multipolar Expansions by Araken S. Werneck (2458621)

“…This methodology is based in the optimization of a damping parameter set using a two-step fast local fitting procedure and the ab initio (Hartree−Fock/6-31G** and 6-31G**+) electrostatic potential calculated in a set of concentric grid of points as reference. …”

The Deoxyhypusine Synthase Mutant <i>dys1-1</i> Reveals the Association of eIF5A and Asc1 with Cell Wall Integrity by Fabio Carrilho Galvão (396804)

“…In this study, we generated and characterized the <i>dys1-1</i> mutant, which showed a strong depletion of mutated Dys1 protein, resulting in more than 2-fold decrease in hypusine levels relative to the wild type. …”

Acridone Derivative 8a Induces Oxidative Stress-Mediated Apoptosis in CCRF-CEM Leukemia Cells: Application of Metabolomics in Mechanistic Studies of Antitumor Agents by Yini Wang (410389)

“…<div><p>A new acridone derivative, 2-aminoacetamido-10-(3, 5-dimethoxy)-benzyl-9(10H)-acridone hydrochloride (named 8a) synthesized in our lab shows potent antitumor activity, but the mechanism of action remains unclear. …”

Image_1_Sex-related differences in adult attention-deficit hyperactivity disorder patients – An analysis of external globus pallidus functional connectivity in resting-state functi... by Gabriele Dupont (13581157)

“…<p>In the last two decades, there has been a growing body of research that identified sex-related differences in attention-deficit hyperactivity disorder (ADHD). …”

Image_3_Sex-related differences in adult attention-deficit hyperactivity disorder patients – An analysis of external globus pallidus functional connectivity in resting-state functi... by Gabriele Dupont (13581157)

“…<p>In the last two decades, there has been a growing body of research that identified sex-related differences in attention-deficit hyperactivity disorder (ADHD). …”

Ultrafast Dynamics and Ultrasensitive Single-Particle Intermittency in Small-Sized Toxic Metal Free InP-Based Core/Alloy-Shell/Shell Quantum Dots: Excitation Wavelength Dependency... by Chayan K. De (7010489)

“…Monitoring the bleach dynamics employing femtosecond ultrafast pump–probe technique, it could be shown that the rise time increases with decrease in pump excitation wavelength from 100 fs for 550 nm excitation to 220 fs for 430 nm pump/excitation. …”

Simultaneous increase in canonical Wnt signaling and suppression of pAKT result in increased apoptosis of CC cells. by Michael Bordonaro (340595)

“…(B) The steady-state levels of transcriptionally active beta-catenin are not decreased in HCT-116 cells by combined treatment with a HDACi and MK2206. …”

DataSheet1_Evaluation of the immune response of peripheral blood mononuclear cells cultured on Ti6Al4V-ELI polished or etched surfaces.pdf by Hugo Abreu (19815654)

“…</p>Discussion<p>The dysregulation of the cytokine profile upon contact with untreated Ti6Al4V-ELI discs, namely upregulation of IL-2 could be responsible for the decrease in Th17 frequency, and thus might contribute to implant-associated bacterial infection. …”

Data_Sheet_1_Genome-Wide Expression Analysis of Glyoxalase I Genes Under Hyperosmotic Stress and Existence of a Stress-Responsive Mitochondrial Glyoxalase I Activity in Durum Wheat... by Mario Soccio (12961406)

“…Expression profile by qRT-PCR analysis revealed that most of the putative active TdGLYI genes were up-regulated by salt and osmotic stress in roots and shoots from 4-day-old seedlings, although a different behavior was observed between the two types of stress and tissue. Accordingly, in the same tissues, hyperosmotic stress induced an increase (up to about 40%) of both GLYI activity and MG content as well as a decrease of GSH (up to about –60%) and an increase of GSSG content (up to about 7-fold) with a consequent strong decrease of the GSH/GSSG ratio (up to about –95%). …”

Table_1_Genome-Wide Expression Analysis of Glyoxalase I Genes Under Hyperosmotic Stress and Existence of a Stress-Responsive Mitochondrial Glyoxalase I Activity in Durum Wheat (Tri... by Mario Soccio (12961406)

“…Expression profile by qRT-PCR analysis revealed that most of the putative active TdGLYI genes were up-regulated by salt and osmotic stress in roots and shoots from 4-day-old seedlings, although a different behavior was observed between the two types of stress and tissue. Accordingly, in the same tissues, hyperosmotic stress induced an increase (up to about 40%) of both GLYI activity and MG content as well as a decrease of GSH (up to about –60%) and an increase of GSSG content (up to about 7-fold) with a consequent strong decrease of the GSH/GSSG ratio (up to about –95%). …”

Data_Sheet_3_Genome-Wide Expression Analysis of Glyoxalase I Genes Under Hyperosmotic Stress and Existence of a Stress-Responsive Mitochondrial Glyoxalase I Activity in Durum Wheat... by Mario Soccio (12961406)

“…Expression profile by qRT-PCR analysis revealed that most of the putative active TdGLYI genes were up-regulated by salt and osmotic stress in roots and shoots from 4-day-old seedlings, although a different behavior was observed between the two types of stress and tissue. Accordingly, in the same tissues, hyperosmotic stress induced an increase (up to about 40%) of both GLYI activity and MG content as well as a decrease of GSH (up to about –60%) and an increase of GSSG content (up to about 7-fold) with a consequent strong decrease of the GSH/GSSG ratio (up to about –95%). …”

Gene-gene interaction network underlying LRO accumulation of Nile red and autofluorescence. by Alexander A. Soukas (476353)

“…(F) RNAi to acyl-coenzyme A synthetase <i>acs-6</i> increases blue autofluorescence in a manner genetically dependent upon TOR complex 2 mutant <i>rict-1</i>. (C–F, N as in table S3 and S4; significance by unequal variance, two-tailed Student's t-test with Bonferroni step-down correction.)…”

Image_1_Genome-Wide Expression Analysis of Glyoxalase I Genes Under Hyperosmotic Stress and Existence of a Stress-Responsive Mitochondrial Glyoxalase I Activity in Durum Wheat (Tri... by Mario Soccio (12961406)

“…Expression profile by qRT-PCR analysis revealed that most of the putative active TdGLYI genes were up-regulated by salt and osmotic stress in roots and shoots from 4-day-old seedlings, although a different behavior was observed between the two types of stress and tissue. Accordingly, in the same tissues, hyperosmotic stress induced an increase (up to about 40%) of both GLYI activity and MG content as well as a decrease of GSH (up to about –60%) and an increase of GSSG content (up to about 7-fold) with a consequent strong decrease of the GSH/GSSG ratio (up to about –95%). …”

Figure2.tif by Wei Hua (6576539)

“…Case One Illustration. (A)CT images showed enlargement of right oval foramen. …”