Neuronal responses to visual stimuli in the proposed microcircuit model with different excitatory/inhibitory (E/I) ratios caused by a change in parvalbumin (PV) inhibitory interneu... by Nobuhiko Wagatsuma (494052)

“…<p>Note that the total number of model neurons in the network remained consistent, irrespective of E/I ratio. <b><i>A.</i></b> Mean population firing rates of Pyr (black triangles in first panel from the left), PV (gray circles in the second panel), somatostatin (SOM; gray pentagons in the third panel), and vasoactive intestinal polypeptide (VIP; gray diamonds in the fourth panel) populations as a function of E/I ratios. …”

Protection by extra virgin olive oil against oxidative stress <i>in vitro</i> and <i>in vivo</i>. Chemical and biological studies on the health benefits due to a major component of... by Miriam Rossi (201573)

“…In addition, EVOO significantly decreased the proliferation of human leukemic THP-1 cells, while it kept the proliferation at about normal levels in rat L6 myoblasts, a non-tumoral skeletal muscle cell line. …”

Enhanced pyruvate dehydrogenase activity improves cardiac outcomes in a murine model of cardiac arrest by Lin Piao (4452487)

“…In both heart and brain, CA increased lactate concentrations (1.9-fold and 3.1-fold increase, respectively, <i>P</i><0.01), decreased PDH enzyme activity (24% and 50% reduction, respectively, <i>P</i><0.01), and increased PDK protein expressions (1.2-fold and 1.9-fold, respectively, <i>P</i><0.01). …”

Hemolysis experiment: osmotic fragility profile of naïve (A) or infected (B) RBCs of day six infected C57BL/6 (white line) or IFNγR-/- (black line) mice. by Jennifer Cnops (385275)

Table 1_Global, regional, and national burdens of rheumatoid arthritis among people aged 60 years and older from 1990 to 2021: a trend analysis for the Global Burden of Disease Stu... by Qin-Yi Su (14188151)

“…Conversely, the age-standardized death rate (ASDR) and age-standardized DALYs rate declined, with ASDR decreasing from 4.18 per 100,000 to 3.20 per 100,000 (95% UI 2.58–3.72), and DALYs rate dropping from 150.83 per 100,000 to 143.20 per 100,000 (95% UI 113.39–178.43). …”

Table 1_The burden and trends of infectious diseases among children aged 14 and below in China from 1990 to 2021: a systematic analysis from the 2021 global burden of disease study... by Chun Guo Miao (21286334)

“…Acute hepatitis mortality decreased from 7,349 deaths (95% UI:5,987–9,059) to 87 (EAPC: −13.78), with a fivefold reduction in ASMR. …”

Data Sheet 1_Psychosocial and physiological health outcomes of outdoor green exercise versus indoor exercise in knee osteoarthritis patients coexisting with type 2 diabetes mellitu... by Yilin Jin (8070026)

“…Participants’ enjoyment of exercise and intention for a future exercise behavior was measured in a questionnaire using a 100mm visual analogue scale as a continuum from 0 – ‘not at all’ to 100 – ‘very much’.…”

FIGURE 4 from D-2-HG Inhibits <i>IDH1^mut</i> Glioma Growth via FTO Inhibition and Resultant m6A Hypermethylation by Sean T. Pianka (18237413)

“…<p>FTO inhibition attenuates gliomasphere growth. <b>A,</b> Increase in U87 RNA m6A content relative to control (0 µmol/L) following the application of FTO inhibitors FB23-2 (left) or MA (right) at various doses. …”

Effects of Tbx5 Paralogues on the Somites. by Erin A. T. Boyle Anderson (6065756)

“…Both Tbx5b-deficient and double-deficient embryos showed a significant decrease in somite size compared to wt embryos. …”

Data Sheet 1_Deciphering a missing piece of the branched-chain amino acids uptake puzzle: YhjE is an L-isoleucine and L-valine transporter in Escherichia coli K-12.docx by Sergey V. Molev (22769330)

“…<p>Branched-chain amino acid (BCAA) uptake in bacteria underpins fitness, pathogenesis, and industrial strain performance, yet the transport landscape, even in Escherichia coli, remains incomplete. Here, we identify and characterize YhjE as a BCAA permease specific for L-isoleucine and L-valine. …”

The basic flowchart of analysis in this study. by Jing Wang (6206297)

“…</p><p>Results</p><p>19 DECAGs were found in AD and the key biological processes and molecular functions associated with AD were further determined. Two subtypes of peripheral blood cells showed significant alternations in AD: Cluster1 and Cluster2. …”

The enriched GO terms of the 19 DECAGs. by Jing Wang (6206297)

“…</p><p>Results</p><p>19 DECAGs were found in AD and the key biological processes and molecular functions associated with AD were further determined. Two subtypes of peripheral blood cells showed significant alternations in AD: Cluster1 and Cluster2. …”

Primers of the tested genes. by Jing Wang (6206297)

“…</p><p>Results</p><p>19 DECAGs were found in AD and the key biological processes and molecular functions associated with AD were further determined. Two subtypes of peripheral blood cells showed significant alternations in AD: Cluster1 and Cluster2. …”

Summary of patient demographic characteristics. by Jing Wang (6206297)

“…</p><p>Results</p><p>19 DECAGs were found in AD and the key biological processes and molecular functions associated with AD were further determined. Two subtypes of peripheral blood cells showed significant alternations in AD: Cluster1 and Cluster2. …”

Table 1_The evolution of the global disease burden of polycystic ovary syndrome and the role of regional heterogeneity in high body mass index exposure: a spatiotemporal analysis b... by Ying Feng (151159)

“…</p>Results<p>In 2021, the global age-standardized prevalence rate (ASPR) of PCOS was 867.7 per 100,000 [95% UI: 618.7–1,195.3], representing a significant increase of 0.75 compared with 1990 [95% CI: 0.71–0.78]. …”

Modelling local immune dynamics during HPV infections. by Nicolas Tessandier (20355027)

“…(B) Illustration of the additional steps for the FCM model. We consider the same two virus genotypes <i>A</i> and <i>B</i> and two hypothetical cell populations: 1, whose trajectory computation is illustrated in panel A, and 2, generated in the same way, with the same <i>t</i>_start, and <i>t</i>_clear, but different <i>ψ</i>s. …”

Data_Sheet_1_Periplasmic Expression of 4/7 α-Conotoxin TxIA Analogs in E. coli Favors Ribbon Isomer Formation – Suggestion of a Binding Mode at the α7 nAChR.ZIP by Yamina El Hamdaoui (6759080)

“…Two-electrode voltage clamp analysis on oocyte-expressed nAChR subtypes demonstrated the functionality of these peptides but also revealed a 30 to 100-fold potency decrease of expressed TxIA compared to chemically synthesized TxIA. …”

IFT88 shRNA shortens cilia and enhances RGC degeneration following ONT. by Brian K. A. Choi (7114916)

“…(D) Representative epifluorescence micrographs of RBPMS immunolabeled RGCs in the inner eccentricity of flatmounted retinas at 7 days post-ONT, expressing control shRNA (top) or IFT88 shRNA (bottom). Scale bar = 100 μm. (E) Quantification of RGCs showing that IFT88 shRNA expression significantly decrease RGC survival at 7 days post ONT, relative to scrambled control hairpin. …”

Data Sheet 1_Global, regional and national burden of decubitus ulcers in 204 countries and territories from 1990 to 2021: a systematic analysis based on the global burden of diseas... by Shenyue Zhang (18472266)

“…The global ASR of prevalence decreased slightly from 8.25 to 7.92 per 100,000 persons, with most cases occurring in individuals aged 60 and older. …”

Incidence of self-reported tuberculosis treatment with community-wide universal testing and treatment for HIV and tuberculosis screening in Zambia and South Africa: A planned analy... by L. Telisinghe (18706323)

“…There was also some evidence this translated to a decrease in self-reported TB incidence overall in the population. …”