COMPARE-MS assay performance by Srinivasan Yegnasubramanian (27577)

“…When 20–100 ng of input DNA are used, COMPARE-MS has a >5000-fold dynamic range, which is ∼500-fold higher than that of methylation-sensitive restriction enzyme used alone and ∼5- to 10-fold higher than that of MBD2-MBD capture used alone. () Plot showing measured output methylated CGIs as determined by COMPARE-MS when decreasing amounts of M.SssI-treated WBC DNA is diluted in 20 ng of untreated WBC genomic DNA. …”

Changes to chromatin state with PRMT5 inhibition. by Shelby L. Sloan (10803222)

“…(D) Immunoblot analysis indicates a time dependent decrease in MYC protein after treatment with C220 in 17–71 (100 nM) and CLBL-1 (20 nM). …”

Nuclear import of Avian Sarcoma Virus integrase is facilitated by host cell factors-2 by Mark D Andrake (95479)

“…Quantitative analysis of nuclear import of various GST fusion proteins with (+ comp) and without (no comp) competitor. More than 100 cells were counted for each experimental condition and the percentage of cells that had a mostly nuclear staining for the fusion protein was calculated. …”

Measurement of the impedance of the HBEC monolayers during coculture with IRBC. by Ronan Jambou (80268)

“…A) show decrease of impedance when HBEC monolayer is co-cultured with IRBC(3Ci) or IRBC(3Ci)+NRBC (vol/vol), but not when co-cultured with normal RBC). …”

The sterile insect technique for the management of the spotted wing drosophila, <i>Drosophila suzukii</i>: Establishing the optimum irradiation dose by Geneviève Lanouette (4476472)

“…<i>suzukii</i> pupae were irradiated 12 to 24 hours prior to adult emergence in a ⁶⁰Co Gamma Cell 220 and in a ¹³⁷Cs Gamma Cell 3000 with doses of 30, 50, 70, 80, 90, 100 or 120 Gy. …”

Quantitative determination of loss of MMP in SH-SY5Y cells in response to Grx1 knockdown. by Uzma Saeed (49670)

“…Cells were treated with vehicle after transfecting them with empty vector, or with vehicle, α-lipoic acid (100 µM) or cyclosporine A (10 µM), 6 hr post transfection with shRNA to Grx1 and MMP was measured using TMRM as the indicator dye. …”

Sequence gaps exclusive to both Archaea and Microsporidia 16S rRNAs. by Chaitanya Muralidhara (223748)

“…(<i>a</i>) The 100 gaps conserved in both the Archaea and Microsporidia map to the entire substructures I–III in the secondary structure model of the bacterium <i>E. coli</i> <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0018768#pone.0018768-Cannone1" target="_blank">[14]</a>. …”

Acute reduction of Ezh2 induces apoptosis in NSCs. by Falak Sher (151989)

“…Immunostaining of dissociated neurospheres in proliferation medium shows a decrease in proliferation and increase in cell death after using Ezh2-shRNA compared to the control (nc-shRNA). …”

Intracellular GSH and GSH/GSSG ratio in monolayer cultures upon induced oxidative stress. by Mireille M. J. P. E. Sthijns (12245491)

“…<p>A) Exposing the monolayer cultures of 0:100, 50:50 and 100:0 INS1E:alphaTC1 cells to 500 μM H₂O₂ only induced a significant decrease in intracellular GSH compared to a monolayer culture not exposed to H₂O₂ in the ratios of 50:50 and 0:100 INS1E:alphaTC1. …”

Long-term trends of potential years of life lost due to main causes of death in the Slovak population, 2004-2013 by Martin Samohyl (10388448)

“…The PYLL rate is age-standardized and expressed as a sum of all deaths per 100,000. In the period 2004-2013, the highest mean PYLL rates were observed in neoplasms in the whole population (2,103 per 100,000), as well as in females (2,088 per 100,000), with a permanent high significant increase of AAPC of PYLL in both genders. …”

Video_1_Concomitant intra-atrial excision of the left atrial appendage during robotic-assisted minimally invasive cardiac surgery.mp4 by Mihnea Ghinescu (14703553)

“…In short, the LAA is invaginated into the left atrium, excised completely at the base using scissors and the stump is then closed from the inside with a two-layer looped PTFE suture. We give a detailed step-by-step description of the technique.…”

The time-dependent currents in <i>Mytilus galloprovincialis</i> hemocytes are modulated by the osmotic pressure. by Monica Bregante (3391766)

“…D) The hyperosmotic bath solution determines a decrease of the steady-state current elicited by V = -100 mV (left bar) without altering the capacitance of the cells (right bar). …”

Supplementary Material for: Early Variation of Respiratory Indexes to Predict Death or ICU Admission in Severe Acute Respiratory Syndrome Coronavirus-2-Related Respiratory Failure by Maraziti G. (12243848)

“…<b><i>Results:</i></b> ROX <3.85 at admission (hazard ratio [HR] 2.95, 95% confidence interval [CI] 1.29–6.77) and decreasing RI or P/F during hospitalization (RI: HR 1.05, 95% CI: 1.00–1.09; P/F: HR 1.01, 95% CI: 1.00–1.02) were predictors of in-hospital death. …”

Marimastat reversed hepatic steatosis in diet-induced obese mice as well as in <i>ob/ob</i> animals, as demonstrated by histology and magnetic resonance spectroscopy. by Vincent E. de Meijer (343377)

“…Histological findings were confirmed with MRS, demonstrating a decrease in fat content in Marimastat-treated animals (A,B bottom panels).…”

The relationship between the parameters <i>ζ</i>/<i>η</i> of the proposed model and the indicators <i>G</i>, 〈<i>h</i>〉, <i>R</i>, and <i>Y</i> for the novelty waves. by Mikihiro Suda (17616078)

“…<p>The gray lines in the plot represent the range of values for <i>η</i> and <i>ζ</i> ranging from 0.1 to 1.0, with a 0.2 step size. The paired values of <i>ρ</i> and <i>ν</i> range from 1 to 30 with a step size of 5, which results in a total of 49 gray lines. …”

Metformin reduces lipid stores and causes intestinal fluid imbalance. by Cathy Slack (251729)

“…<p>(<b>A</b>) Quantitation of triacylglycerides (TAGs) in flies treated with 0 mM, 1 mM, 10 mM and 100 mM metformin for 7 days. …”

αII-Spectrin silencing changes invadosome morphologies. by Aurélie Ponceau (716023)

“…Knockdown of αII-spectrin induces a significant decrease in ring diameters due in particular to an increase in the percentage of rings with a small size and a decrease number of large rings. …”

Immunohistochemical examination of MPO in liver tissue. by Rasha E. Mostafa (11767721)

“…<p>Liver tissues, immunohistochemically stained with anti-MPO antibodies, from <b>(A)</b> sham-operated rats, <b>(B)</b> ovariectomy-control rats didn’t show notable expression of NF-KB in the liver tissue, <b>(C, D)</b> TAA-control rats showing a robust positive result of the stain all over the lobule, <b>(E)</b> rats treated with <i>panax ginseng</i> (100 mg/kg) showing a mild decrease in the positively stained cells, and <b>(F)</b> rats treated with <i>panax ginseng</i> (300 mg/kg) showing a remarkable decrease in the positive result <b>(MPO immunohistochemical staining)</b>.…”

Economic evaluation of an active search system to monitor the outcomes of health-related claims by Nayara Luiza Pereira Rodrigues (8303202)

“…<div><p>ABSTRACT Objective: Economic evaluation of a scientific advisory program with the Public Defenders Office to mitigate the impacts of the judicialization on health in the municipality, as well as the implementation of an active follow-up program to monitor health outcomes arising from court demands. Methods: A two-step study, the first documental, retrospective, with data collection of lawsuits in the region of Barbalha (CE), Brazil, from 2013 to 2018, and the second stage, prospective and intervention, through mediation between the citizen and the Public Defenders Office, aiming to reduce the occurrence of the judicialization, and the monitoring of the health outcomes of the processes. …”

Density of opportunities for recombination initiation along the chromosome. by Thibault Corneloup (16293971)

“…Given the low divergence between strains, when we average the number of these opportunities for recombination per kb across bins of 100kb for each of the tree recipients (REL606, HS and 536), we see that focusing on the 700kb before and after <i>galK</i> locus there are several hundred of opportunities for recombination per kb. …”